3M4EA

Crystal structure of the m113n mutant of alpha-hemolysin bound to beta-cyclodextrin
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYNSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
molecule tags Cell invasion
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 57
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m4eA00
3ANZA 4IDJA 3M2LA 4TW1A 4P1YA 4YHDA 5K59A 4IYCA 3M4EA 3LKFA 4J0OA 4P24A 2YGTA 3M4DA 4H56A 2QK7B 4U6VA 4Q7GA 4P1XB 2LKFA 4IYTA 1LKFA 1T5RA 3M3RA 2QK7A 3B07B 5K59C 1PVLA 4P1XA 4IYAA 4I0NA 3O44A 7AHLA 4IZLA 3B07A 3ROHA 4TW1B 4P1YB
chains in the Genus database with same CATH superfamily
3ANZA 4IDJA 3M2LA 4TW1A 4P1YA 1XEZA 4YHDA 5K59A 4IYCA 3M4EA 3LKFA 4J0OA 4P24A 2YGTA 3M4DA 4H56A 2QK7B 4U6VA 4Q7GA 4P1XB 2LKFA 4IYTA 1LKFA 1T5RA 3M3RA 2QK7A 3B07B 5K59C 1PVLA 4P1XA 4IYAA 4I0NA 3O44A 7AHLA 4IZLA 3B07A 3ROHA 4TW1B 4P1YB
chains in the Genus database with same CATH topology
3ANZA 4IDJA 3M2LA 4TW1A 4P1YA 4YHDA 5K59A 4IYCA 3M4EA 3LKFA 4J0OA 4P24A 2YGTA 3M4DA 4H56A 2QK7B 4U6VA 4Q7GA 4P1XB 2LKFA 4IYTA 1LKFA 1T5RA 3M3RA 2QK7A 3B07B 5K59C 1PVLA 4P1XA 4IYAA 4I0NA 3O44A 7AHLA 4IZLA 3B07A 3ROHA 4TW1B 4P1YB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ANZ A;  4IDJ A;  3M2L A;  4TW1 A;  4P1Y A;  4YHD A;  5K59 A;  4IYC A;  3M4E A;  3LKF A;  4J0O A;  4P24 A;  2YGT A;  3M4D A;  4H56 A;  2QK7 B;  4U6V A;  4Q7G A;  4P1X B;  2LKF A;  4IYT A;  1LKF A;  1T5R A;  3M3R A;  2QK7 A;  3B07 B;  5K59 C;  1PVL A;  4P1X A;  4IYA A;  4I0N A;  3O44 A;  7AHL A;  4IZL A;  3B07 A;  3ROH A;  4TW1 B;  4P1Y B; 
#chains in the Genus database with same CATH topology
 3ANZ A;  4IDJ A;  3M2L A;  4TW1 A;  4P1Y A;  1XEZ A;  4YHD A;  5K59 A;  4IYC A;  3M4E A;  3LKF A;  4J0O A;  4P24 A;  2YGT A;  3M4D A;  4H56 A;  2QK7 B;  4U6V A;  4Q7G A;  4P1X B;  2LKF A;  4IYT A;  1LKF A;  1T5R A;  3M3R A;  2QK7 A;  3B07 B;  5K59 C;  1PVL A;  4P1X A;  4IYA A;  4I0N A;  3O44 A;  7AHL A;  4IZL A;  3B07 A;  3ROH A;  4TW1 B;  4P1Y B; 
#chains in the Genus database with same CATH homology
 3ANZ A;  4IDJ A;  3M2L A;  4TW1 A;  4P1Y A;  4YHD A;  5K59 A;  4IYC A;  3M4E A;  3LKF A;  4J0O A;  4P24 A;  2YGT A;  3M4D A;  4H56 A;  2QK7 B;  4U6V A;  4Q7G A;  4P1X B;  2LKF A;  4IYT A;  1LKF A;  1T5R A;  3M3R A;  2QK7 A;  3B07 B;  5K59 C;  1PVL A;  4P1X A;  4IYA A;  4I0N A;  3O44 A;  7AHL A;  4IZL A;  3B07 A;  3ROH A;  4TW1 B;  4P1Y B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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