3M4EA

Crystal structure of the m113n mutant of alpha-hemolysin bound to beta-cyclodextrin
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYNSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
molecule tags Cell invasion
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 57
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m4eA00
5K59A 4TW1A 2YGTA 3O44A 4IZLA 1PVLA 4P1YA 4P1XA 4U6VA 4IYCA 3LKFA 4J0OA 4IYAA 3M3RA 3M4DA 3M2LA 4IDJA 2LKFA 4YHDA 5K59C 4IYTA 3M4EA 1T5RA 1LKFA 7AHLA 2QK7B 3B07B 4I0NA 3ROHA 4Q7GA 3ANZA 4TW1B 4H56A 2QK7A 4P24A 4P1YB 3B07A 4P1XB
chains in the Genus database with same CATH superfamily
5K59A 4TW1A 2YGTA 3O44A 4IZLA 1PVLA 4P1YA 4P1XA 4U6VA 4IYCA 3LKFA 4J0OA 4IYAA 3M3RA 3M4DA 3M2LA 4IDJA 2LKFA 4YHDA 5K59C 4IYTA 3M4EA 1T5RA 1LKFA 7AHLA 2QK7B 1XEZA 3B07B 4I0NA 3ROHA 4Q7GA 3ANZA 4TW1B 4H56A 2QK7A 4P24A 4P1YB 3B07A 4P1XB
chains in the Genus database with same CATH topology
5K59A 4TW1A 2YGTA 3O44A 4IZLA 1PVLA 4P1YA 4P1XA 4U6VA 4IYCA 3LKFA 4J0OA 4IYAA 3M3RA 3M4DA 3M2LA 4IDJA 2LKFA 4YHDA 5K59C 4IYTA 3M4EA 1T5RA 1LKFA 7AHLA 2QK7B 3B07B 4I0NA 3ROHA 4Q7GA 3ANZA 4TW1B 4H56A 2QK7A 4P24A 4P1YB 3B07A 4P1XB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K59 A;  4TW1 A;  2YGT A;  3O44 A;  4IZL A;  1PVL A;  4P1Y A;  4P1X A;  4U6V A;  4IYC A;  3LKF A;  4J0O A;  4IYA A;  3M3R A;  3M4D A;  3M2L A;  4IDJ A;  2LKF A;  4YHD A;  5K59 C;  4IYT A;  3M4E A;  1T5R A;  1LKF A;  7AHL A;  2QK7 B;  3B07 B;  4I0N A;  3ROH A;  4Q7G A;  3ANZ A;  4TW1 B;  4H56 A;  2QK7 A;  4P24 A;  4P1Y B;  3B07 A;  4P1X B; 
#chains in the Genus database with same CATH topology
 5K59 A;  4TW1 A;  2YGT A;  3O44 A;  4IZL A;  1PVL A;  4P1Y A;  4P1X A;  4U6V A;  4IYC A;  3LKF A;  4J0O A;  4IYA A;  3M3R A;  3M4D A;  3M2L A;  4IDJ A;  2LKF A;  4YHD A;  5K59 C;  4IYT A;  3M4E A;  1T5R A;  1LKF A;  7AHL A;  2QK7 B;  1XEZ A;  3B07 B;  4I0N A;  3ROH A;  4Q7G A;  3ANZ A;  4TW1 B;  4H56 A;  2QK7 A;  4P24 A;  4P1Y B;  3B07 A;  4P1X B; 
#chains in the Genus database with same CATH homology
 5K59 A;  4TW1 A;  2YGT A;  3O44 A;  4IZL A;  1PVL A;  4P1Y A;  4P1X A;  4U6V A;  4IYC A;  3LKF A;  4J0O A;  4IYA A;  3M3R A;  3M4D A;  3M2L A;  4IDJ A;  2LKF A;  4YHD A;  5K59 C;  4IYT A;  3M4E A;  1T5R A;  1LKF A;  7AHL A;  2QK7 B;  3B07 B;  4I0N A;  3ROH A;  4Q7G A;  3ANZ A;  4TW1 B;  4H56 A;  2QK7 A;  4P24 A;  4P1Y B;  3B07 A;  4P1X B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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