3S4MA

Crystal structure of wild-type human frataxin
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
121
structure length
121
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 35
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3s4mA00
1SOYA 2EFFA 3S5FA 3T3XA 4EC2A 3S4MA 2P1XA 3T3LA 3OEQA 4LK8A 3T3KA 3T3TA 4LP1A 3S5DA 1LY7A 4HS5A 2FQLA 3OERA 3T3JA 4JPDA 1EW4A 2GA5A 1EKGA 3S5EA
chains in the Genus database with same CATH superfamily
3S5EA 1SOYA 3IAM7 3IMOA 2EFFA 3S5FA 3T3XA 4EC2A 3SSEA 3S4MA 2P1XA 3T3LA 1D2MA 3OEQA 4LK8A 4P78C 3T3KA 3T3TA 4LP1A 3S5DA 3IAS7 1LY7A 3A5PA 1V5RA 4HS5A 3SSDA 3SSCA 2FQLA 3GD0A 3OERA 3I9V7 3T3JA 4JPDA 1EW4A 2GA5A 3GD9A 1WHZA 2FUG7 4C26A 1EKGA 4HEA7
chains in the Genus database with same CATH topology
1SOYA 2EFFA 3S5FA 3T3XA 4EC2A 3S4MA 2P1XA 3T3LA 3OEQA 4LK8A 3T3KA 3T3TA 4LP1A 3S5DA 1LY7A 4HS5A 2FQLA 3OERA 3T3JA 4JPDA 1EW4A 2GA5A 1EKGA 3S5EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SOY A;  2EFF A;  3S5F A;  3T3X A;  4EC2 A;  3S4M A;  2P1X A;  3T3L A;  3OEQ A;  4LK8 A;  3T3K A;  3T3T A;  4LP1 A;  3S5D A;  1LY7 A;  4HS5 A;  2FQL A;  3OER A;  3T3J A;  4JPD A;  1EW4 A;  2GA5 A;  1EKG A;  3S5E A; 
#chains in the Genus database with same CATH topology
 3S5E A;  1SOY A;  3IAM 7;  3IMO A;  2EFF A;  3S5F A;  3T3X A;  4EC2 A;  3SSE A;  3S4M A;  2P1X A;  3T3L A;  1D2M A;  3OEQ A;  4LK8 A;  4P78 C;  3T3K A;  3T3T A;  4LP1 A;  3S5D A;  3IAS 7;  1LY7 A;  3A5P A;  1V5R A;  4HS5 A;  3SSD A;  3SSC A;  2FQL A;  3GD0 A;  3OER A;  3I9V 7;  3T3J A;  4JPD A;  1EW4 A;  2GA5 A;  3GD9 A;  1WHZ A;  2FUG 7;  4C26 A;  1EKG A;  4HEA 7; 
#chains in the Genus database with same CATH homology
 1SOY A;  2EFF A;  3S5F A;  3T3X A;  4EC2 A;  3S4M A;  2P1X A;  3T3L A;  3OEQ A;  4LK8 A;  3T3K A;  3T3T A;  4LP1 A;  3S5D A;  1LY7 A;  4HS5 A;  2FQL A;  3OER A;  3T3J A;  4JPD A;  1EW4 A;  2GA5 A;  1EKG A;  3S5E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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