3S5DA

Crystal structure of human frataxin variant w155a
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
121
structure length
121
Chain Sequence
LDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIALSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 34
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3s5dA00
3OERA 1EW4A 4LK8A 4JPDA 4LP1A 2GA5A 2FQLA 3T3XA 3S4MA 3T3KA 1EKGA 2P1XA 2EFFA 1SOYA 3S5EA 3T3TA 3T3LA 3OEQA 4EC2A 3S5FA 3S5DA 1LY7A 4HS5A 3T3JA
chains in the Genus database with same CATH superfamily
3OERA 1EW4A 3IAS7 4LK8A 4JPDA 4LP1A 2GA5A 1WHZA 2FQLA 3T3XA 3S4MA 3T3KA 3SSCA 1EKGA 2P1XA 4C26A 3I9V7 2EFFA 1SOYA 3S5EA 3IAM7 3GD0A 3T3TA 3T3LA 3OEQA 4EC2A 4HEA7 3IMOA 3GD9A 3S5FA 3S5DA 1D2MA 1LY7A 4P78C 3SSEA 2FUG7 3SSDA 3A5PA 1V5RA 4HS5A 3T3JA
chains in the Genus database with same CATH topology
3OERA 1EW4A 4LK8A 4JPDA 4LP1A 2GA5A 2FQLA 3T3XA 3S4MA 3T3KA 1EKGA 2P1XA 2EFFA 1SOYA 3S5EA 3T3TA 3T3LA 3OEQA 4EC2A 3S5FA 3S5DA 1LY7A 4HS5A 3T3JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OER A;  1EW4 A;  4LK8 A;  4JPD A;  4LP1 A;  2GA5 A;  2FQL A;  3T3X A;  3S4M A;  3T3K A;  1EKG A;  2P1X A;  2EFF A;  1SOY A;  3S5E A;  3T3T A;  3T3L A;  3OEQ A;  4EC2 A;  3S5F A;  3S5D A;  1LY7 A;  4HS5 A;  3T3J A; 
#chains in the Genus database with same CATH topology
 3OER A;  1EW4 A;  3IAS 7;  4LK8 A;  4JPD A;  4LP1 A;  2GA5 A;  1WHZ A;  2FQL A;  3T3X A;  3S4M A;  3T3K A;  3SSC A;  1EKG A;  2P1X A;  4C26 A;  3I9V 7;  2EFF A;  1SOY A;  3S5E A;  3IAM 7;  3GD0 A;  3T3T A;  3T3L A;  3OEQ A;  4EC2 A;  4HEA 7;  3IMO A;  3GD9 A;  3S5F A;  3S5D A;  1D2M A;  1LY7 A;  4P78 C;  3SSE A;  2FUG 7;  3SSD A;  3A5P A;  1V5R A;  4HS5 A;  3T3J A; 
#chains in the Genus database with same CATH homology
 3OER A;  1EW4 A;  4LK8 A;  4JPD A;  4LP1 A;  2GA5 A;  2FQL A;  3T3X A;  3S4M A;  3T3K A;  1EKG A;  2P1X A;  2EFF A;  1SOY A;  3S5E A;  3T3T A;  3T3L A;  3OEQ A;  4EC2 A;  3S5F A;  3S5D A;  1LY7 A;  4HS5 A;  3T3J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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