3S5FA

Crystal structure of human frataxin variant w155f
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
120
structure length
120
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIFLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 33
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3s5fA00
3OEQA 2GA5A 2EFFA 3T3LA 3S5DA 3T3JA 3OERA 1EKGA 1LY7A 4LP1A 3T3KA 1SOYA 2P1XA 4EC2A 3S4MA 3S5FA 3T3TA 4HS5A 3T3XA 4JPDA 1EW4A 3S5EA 4LK8A 2FQLA
chains in the Genus database with same CATH superfamily
3OEQA 4P78C 2GA5A 3IMOA 2FUG7 3SSCA 3IAS7 2EFFA 3T3LA 1V5RA 3S5DA 3T3JA 3OERA 4HEA7 1EKGA 1LY7A 1D2MA 3GD9A 4LP1A 3T3KA 1SOYA 3A5PA 3I9V7 3SSDA 2P1XA 3SSEA 4EC2A 3S4MA 3S5FA 1WHZA 4HS5A 3T3TA 3GD0A 4JPDA 3T3XA 4C26A 1EW4A 3S5EA 4LK8A 2FQLA 3IAM7
chains in the Genus database with same CATH topology
3OEQA 2GA5A 2EFFA 3T3LA 3S5DA 3T3JA 3OERA 1EKGA 1LY7A 4LP1A 3T3KA 1SOYA 2P1XA 4EC2A 3S4MA 3S5FA 3T3TA 4HS5A 3T3XA 4JPDA 1EW4A 3S5EA 4LK8A 2FQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OEQ A;  2GA5 A;  2EFF A;  3T3L A;  3S5D A;  3T3J A;  3OER A;  1EKG A;  1LY7 A;  4LP1 A;  3T3K A;  1SOY A;  2P1X A;  4EC2 A;  3S4M A;  3S5F A;  3T3T A;  4HS5 A;  3T3X A;  4JPD A;  1EW4 A;  3S5E A;  4LK8 A;  2FQL A; 
#chains in the Genus database with same CATH topology
 3OEQ A;  4P78 C;  2GA5 A;  3IMO A;  2FUG 7;  3SSC A;  3IAS 7;  2EFF A;  3T3L A;  1V5R A;  3S5D A;  3T3J A;  3OER A;  4HEA 7;  1EKG A;  1LY7 A;  1D2M A;  3GD9 A;  4LP1 A;  3T3K A;  1SOY A;  3A5P A;  3I9V 7;  3SSD A;  2P1X A;  3SSE A;  4EC2 A;  3S4M A;  3S5F A;  1WHZ A;  4HS5 A;  3T3T A;  3GD0 A;  4JPD A;  3T3X A;  4C26 A;  1EW4 A;  3S5E A;  4LK8 A;  2FQL A;  3IAM 7; 
#chains in the Genus database with same CATH homology
 3OEQ A;  2GA5 A;  2EFF A;  3T3L A;  3S5D A;  3T3J A;  3OER A;  1EKG A;  1LY7 A;  4LP1 A;  3T3K A;  1SOY A;  2P1X A;  4EC2 A;  3S4M A;  3S5F A;  3T3T A;  4HS5 A;  3T3X A;  4JPD A;  1EW4 A;  3S5E A;  4LK8 A;  2FQL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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