3T3JA

1.70 a structure of friedreich's ataxia frataxin variant n146k
Total Genus 36
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
123
structure length
123
Chain Sequence
HPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVIKKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 36
structure length 123
sequence length 123
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3jA00
4JPDA 2FQLA 3T3XA 2P1XA 2EFFA 4LK8A 4LP1A 3T3TA 3S5FA 1SOYA 1EW4A 1LY7A 3S5DA 3S5EA 3S4MA 2GA5A 3OEQA 3T3LA 4EC2A 4HS5A 1EKGA 3OERA 3T3JA 3T3KA
chains in the Genus database with same CATH superfamily
3IAS7 2FUG7 4JPDA 2FQLA 3T3XA 2P1XA 2EFFA 4LK8A 4LP1A 3T3TA 1D2MA 3GD9A 3GD0A 3S5FA 1SOYA 1EW4A 3SSEA 1LY7A 4C26A 3S5DA 3I9V7 3SSCA 4HEA7 3S5EA 3S4MA 2GA5A 3OEQA 3T3LA 4EC2A 4HS5A 3IAM7 3IMOA 4P78C 1EKGA 3OERA 3T3JA 3A5PA 3T3KA 3SSDA 1V5RA 1WHZA
chains in the Genus database with same CATH topology
4JPDA 2FQLA 3T3XA 2P1XA 2EFFA 4LK8A 4LP1A 3T3TA 3S5FA 1SOYA 1EW4A 1LY7A 3S5DA 3S5EA 3S4MA 2GA5A 3OEQA 3T3LA 4EC2A 4HS5A 1EKGA 3OERA 3T3JA 3T3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JPD A;  2FQL A;  3T3X A;  2P1X A;  2EFF A;  4LK8 A;  4LP1 A;  3T3T A;  3S5F A;  1SOY A;  1EW4 A;  1LY7 A;  3S5D A;  3S5E A;  3S4M A;  2GA5 A;  3OEQ A;  3T3L A;  4EC2 A;  4HS5 A;  1EKG A;  3OER A;  3T3J A;  3T3K A; 
#chains in the Genus database with same CATH topology
 3IAS 7;  2FUG 7;  4JPD A;  2FQL A;  3T3X A;  2P1X A;  2EFF A;  4LK8 A;  4LP1 A;  3T3T A;  1D2M A;  3GD9 A;  3GD0 A;  3S5F A;  1SOY A;  1EW4 A;  3SSE A;  1LY7 A;  4C26 A;  3S5D A;  3I9V 7;  3SSC A;  4HEA 7;  3S5E A;  3S4M A;  2GA5 A;  3OEQ A;  3T3L A;  4EC2 A;  4HS5 A;  3IAM 7;  3IMO A;  4P78 C;  1EKG A;  3OER A;  3T3J A;  3A5P A;  3T3K A;  3SSD A;  1V5R A;  1WHZ A; 
#chains in the Genus database with same CATH homology
 4JPD A;  2FQL A;  3T3X A;  2P1X A;  2EFF A;  4LK8 A;  4LP1 A;  3T3T A;  3S5F A;  1SOY A;  1EW4 A;  1LY7 A;  3S5D A;  3S5E A;  3S4M A;  2GA5 A;  3OEQ A;  3T3L A;  4EC2 A;  4HS5 A;  1EKG A;  3OER A;  3T3J A;  3T3K A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...