3T3KA

1.24 a structure of friedreich's ataxia frataxin variant q148r
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKRTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 34
structure length 122
sequence length 122
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3kA00
3T3XA 3OERA 3T3KA 1SOYA 1LY7A 4JPDA 3T3TA 3S5DA 2GA5A 4EC2A 4HS5A 3T3JA 3S4MA 3T3LA 2FQLA 2EFFA 1EW4A 3S5EA 3OEQA 1EKGA 2P1XA 4LK8A 3S5FA 4LP1A
chains in the Genus database with same CATH superfamily
3T3XA 3SSEA 3OERA 3IMOA 3T3KA 3GD9A 2FUG7 1SOYA 1LY7A 4JPDA 3T3TA 3S5DA 4C26A 2GA5A 4EC2A 1WHZA 4HS5A 3T3JA 3S4MA 4HEA7 3SSDA 3T3LA 1V5RA 3SSCA 2FQLA 2EFFA 1EW4A 3S5EA 3I9V7 4P78C 3OEQA 1D2MA 1EKGA 2P1XA 3IAM7 4LK8A 3A5PA 3GD0A 3S5FA 4LP1A 3IAS7
chains in the Genus database with same CATH topology
3T3XA 3OERA 3T3KA 1SOYA 1LY7A 4JPDA 3T3TA 3S5DA 2GA5A 4EC2A 4HS5A 3T3JA 3S4MA 3T3LA 2FQLA 2EFFA 1EW4A 3S5EA 3OEQA 1EKGA 2P1XA 4LK8A 3S5FA 4LP1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3X A;  3OER A;  3T3K A;  1SOY A;  1LY7 A;  4JPD A;  3T3T A;  3S5D A;  2GA5 A;  4EC2 A;  4HS5 A;  3T3J A;  3S4M A;  3T3L A;  2FQL A;  2EFF A;  1EW4 A;  3S5E A;  3OEQ A;  1EKG A;  2P1X A;  4LK8 A;  3S5F A;  4LP1 A; 
#chains in the Genus database with same CATH topology
 3T3X A;  3SSE A;  3OER A;  3IMO A;  3T3K A;  3GD9 A;  2FUG 7;  1SOY A;  1LY7 A;  4JPD A;  3T3T A;  3S5D A;  4C26 A;  2GA5 A;  4EC2 A;  1WHZ A;  4HS5 A;  3T3J A;  3S4M A;  4HEA 7;  3SSD A;  3T3L A;  1V5R A;  3SSC A;  2FQL A;  2EFF A;  1EW4 A;  3S5E A;  3I9V 7;  4P78 C;  3OEQ A;  1D2M A;  1EKG A;  2P1X A;  3IAM 7;  4LK8 A;  3A5P A;  3GD0 A;  3S5F A;  4LP1 A;  3IAS 7; 
#chains in the Genus database with same CATH homology
 3T3X A;  3OER A;  3T3K A;  1SOY A;  1LY7 A;  4JPD A;  3T3T A;  3S5D A;  2GA5 A;  4EC2 A;  4HS5 A;  3T3J A;  3S4M A;  3T3L A;  2FQL A;  2EFF A;  1EW4 A;  3S5E A;  3OEQ A;  1EKG A;  2P1X A;  4LK8 A;  3S5F A;  4LP1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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