3T3KA

1.24 a structure of friedreich's ataxia frataxin variant q148r
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKRTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule keywords Frataxin, mitochondrial
molecule tags Oxidoreductase
source organism Homo sapiens
total genus 34
structure length 122
sequence length 122
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3kA00
2GA5A 3T3LA 3S5EA 2FQLA 3T3TA 4LK8A 4EC2A 3OERA 4JPDA 3S5DA 4LP1A 3T3JA 1EW4A 1LY7A 1SOYA 3OEQA 3S5FA 1EKGA 3S4MA 2P1XA 4HS5A 3T3KA 3T3XA 2EFFA
chains in the Genus database with same CATH superfamily
2GA5A 3T3LA 3SSCA 3SSDA 3S5EA 2FQLA 3T3TA 1D2MA 4LK8A 4EC2A 3T3XA 3SSEA 3OERA 4JPDA 3S5DA 4LP1A 3GD9A 3IMOA 3T3JA 1EW4A 1LY7A 3GD0A 4HEA7 4P78C 1SOYA 3OEQA 3I9V7 4C26A 3S5FA 1WHZA 1EKGA 2FUG7 3IAS7 3S4MA 2P1XA 3IAM7 4HS5A 1V5RA 3T3KA 3A5PA 2EFFA
chains in the Genus database with same CATH topology
2GA5A 3T3LA 3S5EA 2FQLA 3T3TA 4LK8A 4EC2A 3OERA 4JPDA 3S5DA 4LP1A 3T3JA 1EW4A 1LY7A 1SOYA 3OEQA 3S5FA 1EKGA 3S4MA 2P1XA 4HS5A 3T3KA 3T3XA 2EFFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GA5 A;  3T3L A;  3S5E A;  2FQL A;  3T3T A;  4LK8 A;  4EC2 A;  3OER A;  4JPD A;  3S5D A;  4LP1 A;  3T3J A;  1EW4 A;  1LY7 A;  1SOY A;  3OEQ A;  3S5F A;  1EKG A;  3S4M A;  2P1X A;  4HS5 A;  3T3K A;  3T3X A;  2EFF A; 
#chains in the Genus database with same CATH topology
 2GA5 A;  3T3L A;  3SSC A;  3SSD A;  3S5E A;  2FQL A;  3T3T A;  1D2M A;  4LK8 A;  4EC2 A;  3T3X A;  3SSE A;  3OER A;  4JPD A;  3S5D A;  4LP1 A;  3GD9 A;  3IMO A;  3T3J A;  1EW4 A;  1LY7 A;  3GD0 A;  4HEA 7;  4P78 C;  1SOY A;  3OEQ A;  3I9V 7;  4C26 A;  3S5F A;  1WHZ A;  1EKG A;  2FUG 7;  3IAS 7;  3S4M A;  2P1X A;  3IAM 7;  4HS5 A;  1V5R A;  3T3K A;  3A5P A;  2EFF A; 
#chains in the Genus database with same CATH homology
 2GA5 A;  3T3L A;  3S5E A;  2FQL A;  3T3T A;  4LK8 A;  4EC2 A;  3OER A;  4JPD A;  3S5D A;  4LP1 A;  3T3J A;  1EW4 A;  1LY7 A;  1SOY A;  3OEQ A;  3S5F A;  1EKG A;  3S4M A;  2P1X A;  4HS5 A;  3T3K A;  3T3X A;  2EFF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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