3T3TA

1.38 a structure of human frataxin variant q148g
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
120
structure length
120
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKGTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule keywords Frataxin, mitochondrial
molecule tags Oxidoreductase
source organism Homo sapiens
total genus 36
structure length 120
sequence length 120
chains with identical sequence B, C, D
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3tA00
3T3TA 4LP1A 4LK8A 3S5DA 2EFFA 4JPDA 1SOYA 1LY7A 1EW4A 3T3XA 3T3KA 3T3JA 2FQLA 4EC2A 4HS5A 3OERA 3T3LA 3S5FA 3OEQA 3S4MA 2GA5A 3S5EA 1EKGA 2P1XA
chains in the Genus database with same CATH superfamily
3T3TA 3IAM7 4C26A 4LP1A 4LK8A 3S5DA 2EFFA 3GD0A 4JPDA 3SSDA 4P78C 1WHZA 1SOYA 3A5PA 4HEA7 1LY7A 3IAS7 1EW4A 3T3XA 2FUG7 3T3KA 3IMOA 3T3JA 3GD9A 1V5RA 2FQLA 4EC2A 4HS5A 3OERA 3T3LA 3SSCA 3S5FA 1D2MA 3OEQA 3S4MA 3SSEA 2GA5A 3S5EA 1EKGA 3I9V7 2P1XA
chains in the Genus database with same CATH topology
3T3TA 4LP1A 4LK8A 3S5DA 2EFFA 4JPDA 1SOYA 1LY7A 1EW4A 3T3XA 3T3KA 3T3JA 2FQLA 4EC2A 4HS5A 3OERA 3T3LA 3S5FA 3OEQA 3S4MA 2GA5A 3S5EA 1EKGA 2P1XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3T A;  4LP1 A;  4LK8 A;  3S5D A;  2EFF A;  4JPD A;  1SOY A;  1LY7 A;  1EW4 A;  3T3X A;  3T3K A;  3T3J A;  2FQL A;  4EC2 A;  4HS5 A;  3OER A;  3T3L A;  3S5F A;  3OEQ A;  3S4M A;  2GA5 A;  3S5E A;  1EKG A;  2P1X A; 
#chains in the Genus database with same CATH topology
 3T3T A;  3IAM 7;  4C26 A;  4LP1 A;  4LK8 A;  3S5D A;  2EFF A;  3GD0 A;  4JPD A;  3SSD A;  4P78 C;  1WHZ A;  1SOY A;  3A5P A;  4HEA 7;  1LY7 A;  3IAS 7;  1EW4 A;  3T3X A;  2FUG 7;  3T3K A;  3IMO A;  3T3J A;  3GD9 A;  1V5R A;  2FQL A;  4EC2 A;  4HS5 A;  3OER A;  3T3L A;  3SSC A;  3S5F A;  1D2M A;  3OEQ A;  3S4M A;  3SSE A;  2GA5 A;  3S5E A;  1EKG A;  3I9V 7;  2P1X A; 
#chains in the Genus database with same CATH homology
 3T3T A;  4LP1 A;  4LK8 A;  3S5D A;  2EFF A;  4JPD A;  1SOY A;  1LY7 A;  1EW4 A;  3T3X A;  3T3K A;  3T3J A;  2FQL A;  4EC2 A;  4HS5 A;  3OER A;  3T3L A;  3S5F A;  3OEQ A;  3S4M A;  2GA5 A;  3S5E A;  1EKG A;  2P1X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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