3T3XA

1.57 a structure of friedreich's ataxia frataxin variant r165c
Total Genus 35
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKCYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule keywords Frataxin, mitochondrial
molecule tags Oxidoreductase
source organism Homo sapiens
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3xA00
3T3TA 1SOYA 2FQLA 3S5FA 1LY7A 2P1XA 4LP1A 3S5EA 3S5DA 3OEQA 2EFFA 4EC2A 3T3LA 4HS5A 4JPDA 3T3XA 1EW4A 3T3JA 3T3KA 2GA5A 4LK8A 3S4MA 3OERA 1EKGA
chains in the Genus database with same CATH superfamily
3T3TA 1SOYA 2FQLA 3A5PA 3GD9A 3I9V7 3S5FA 1LY7A 1V5RA 3IMOA 2P1XA 4LP1A 3S5EA 3S5DA 1D2MA 3OEQA 1WHZA 2EFFA 4EC2A 2FUG7 3T3LA 3IAS7 4P78C 4HS5A 4JPDA 3T3XA 3SSDA 1EW4A 4HEA7 3T3JA 3T3KA 4C26A 2GA5A 3SSEA 4LK8A 3S4MA 3OERA 3SSCA 3IAM7 1EKGA 3GD0A
chains in the Genus database with same CATH topology
3T3TA 1SOYA 2FQLA 3S5FA 1LY7A 2P1XA 4LP1A 3S5EA 3S5DA 3OEQA 2EFFA 4EC2A 3T3LA 4HS5A 4JPDA 3T3XA 1EW4A 3T3JA 3T3KA 2GA5A 4LK8A 3S4MA 3OERA 1EKGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3T A;  1SOY A;  2FQL A;  3S5F A;  1LY7 A;  2P1X A;  4LP1 A;  3S5E A;  3S5D A;  3OEQ A;  2EFF A;  4EC2 A;  3T3L A;  4HS5 A;  4JPD A;  3T3X A;  1EW4 A;  3T3J A;  3T3K A;  2GA5 A;  4LK8 A;  3S4M A;  3OER A;  1EKG A; 
#chains in the Genus database with same CATH topology
 3T3T A;  1SOY A;  2FQL A;  3A5P A;  3GD9 A;  3I9V 7;  3S5F A;  1LY7 A;  1V5R A;  3IMO A;  2P1X A;  4LP1 A;  3S5E A;  3S5D A;  1D2M A;  3OEQ A;  1WHZ A;  2EFF A;  4EC2 A;  2FUG 7;  3T3L A;  3IAS 7;  4P78 C;  4HS5 A;  4JPD A;  3T3X A;  3SSD A;  1EW4 A;  4HEA 7;  3T3J A;  3T3K A;  4C26 A;  2GA5 A;  3SSE A;  4LK8 A;  3S4M A;  3OER A;  3SSC A;  3IAM 7;  1EKG A;  3GD0 A; 
#chains in the Genus database with same CATH homology
 3T3T A;  1SOY A;  2FQL A;  3S5F A;  1LY7 A;  2P1X A;  4LP1 A;  3S5E A;  3S5D A;  3OEQ A;  2EFF A;  4EC2 A;  3T3L A;  4HS5 A;  4JPD A;  3T3X A;  1EW4 A;  3T3J A;  3T3K A;  2GA5 A;  4LK8 A;  3S4M A;  3OER A;  1EKG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...