3S5EA

Crystal structure of human frataxin variant w155r, one of the friedreich's ataxia point mutations
Total Genus 32
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
121
structure length
121
Chain Sequence
GSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIRLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 32
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3s5eA00
3T3KA 2EFFA 1EW4A 1EKGA 1SOYA 3OERA 3S4MA 3T3JA 1LY7A 3S5DA 3OEQA 3S5FA 2P1XA 4EC2A 4JPDA 3T3TA 4HS5A 4LP1A 4LK8A 3T3XA 3S5EA 2GA5A 3T3LA 2FQLA
chains in the Genus database with same CATH superfamily
3T3KA 2EFFA 1EW4A 3A5PA 1EKGA 1SOYA 3SSDA 3OERA 3S4MA 3T3JA 4C26A 1LY7A 3GD0A 3IAM7 3S5DA 3OEQA 3S5FA 2P1XA 4EC2A 4JPDA 4HEA7 3T3TA 3SSCA 3IMOA 3I9V7 3GD9A 3SSEA 4HS5A 4LP1A 2FUG7 4LK8A 3T3XA 3S5EA 1V5RA 1D2MA 1WHZA 3IAS7 4P78C 2GA5A 3T3LA 2FQLA
chains in the Genus database with same CATH topology
3T3KA 2EFFA 1EW4A 1EKGA 1SOYA 3OERA 3S4MA 3T3JA 1LY7A 3S5DA 3OEQA 3S5FA 2P1XA 4EC2A 4JPDA 3T3TA 4HS5A 4LP1A 4LK8A 3T3XA 3S5EA 2GA5A 3T3LA 2FQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3K A;  2EFF A;  1EW4 A;  1EKG A;  1SOY A;  3OER A;  3S4M A;  3T3J A;  1LY7 A;  3S5D A;  3OEQ A;  3S5F A;  2P1X A;  4EC2 A;  4JPD A;  3T3T A;  4HS5 A;  4LP1 A;  4LK8 A;  3T3X A;  3S5E A;  2GA5 A;  3T3L A;  2FQL A; 
#chains in the Genus database with same CATH topology
 3T3K A;  2EFF A;  1EW4 A;  3A5P A;  1EKG A;  1SOY A;  3SSD A;  3OER A;  3S4M A;  3T3J A;  4C26 A;  1LY7 A;  3GD0 A;  3IAM 7;  3S5D A;  3OEQ A;  3S5F A;  2P1X A;  4EC2 A;  4JPD A;  4HEA 7;  3T3T A;  3SSC A;  3IMO A;  3I9V 7;  3GD9 A;  3SSE A;  4HS5 A;  4LP1 A;  2FUG 7;  4LK8 A;  3T3X A;  3S5E A;  1V5R A;  1D2M A;  1WHZ A;  3IAS 7;  4P78 C;  2GA5 A;  3T3L A;  2FQL A; 
#chains in the Genus database with same CATH homology
 3T3K A;  2EFF A;  1EW4 A;  1EKG A;  1SOY A;  3OER A;  3S4M A;  3T3J A;  1LY7 A;  3S5D A;  3OEQ A;  3S5F A;  2P1X A;  4EC2 A;  4JPD A;  3T3T A;  4HS5 A;  4LP1 A;  4LK8 A;  3T3X A;  3S5E A;  2GA5 A;  3T3L A;  2FQL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...