3T3JA

1.70 a structure of friedreich's ataxia frataxin variant n146k
Total Genus 36

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
123
structure length
123
Chain Sequence
HPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVIKKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (92-114)TI1 (116-119)TI2 (120-123)EMPTYUpdating...
connected with : NaN
molecule tags Oxidoreductase
source organism Homo sapiens
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule keywords Frataxin, mitochondrial
total genus 36
structure length 123
sequence length 123
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3jA00
4HS5A 3T3JA 4EC2A 2FQLA 3OERA 3OEQA 1EKGA 4LP1A 3T3LA 2P1XA 3T3TA 3S5DA 3T3XA 1EW4A 4JPDA 2EFFA 3S5EA 3S5FA 2GA5A 3S4MA 4LK8A 1SOYA 1LY7A 3T3KA
chains in the Genus database with same CATH superfamily
4HEA7 4HS5A 1V5RA 3T3JA 3SSEA 2FUG7 4EC2A 3IMOA 3IAS7 3GD0A 2FQLA 3SSDA 3SSCA 3OERA 3OEQA 1EKGA 4LP1A 3T3LA 2P1XA 3T3TA 3I9V7 3S5DA 3A5PA 1WHZA 3IAM7 1EW4A 3T3XA 3GD9A 4JPDA 2EFFA 3S5EA 4C26A 4P78C 3S5FA 2GA5A 1D2MA 3S4MA 4LK8A 1SOYA 1LY7A 3T3KA
chains in the Genus database with same CATH topology
4HS5A 3T3JA 4EC2A 2FQLA 3OERA 3OEQA 1EKGA 4LP1A 3T3LA 2P1XA 3T3TA 3S5DA 3T3XA 1EW4A 4JPDA 2EFFA 3S5EA 3S5FA 2GA5A 3S4MA 4LK8A 1SOYA 1LY7A 3T3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HS5 A;  3T3J A;  4EC2 A;  2FQL A;  3OER A;  3OEQ A;  1EKG A;  4LP1 A;  3T3L A;  2P1X A;  3T3T A;  3S5D A;  3T3X A;  1EW4 A;  4JPD A;  2EFF A;  3S5E A;  3S5F A;  2GA5 A;  3S4M A;  4LK8 A;  1SOY A;  1LY7 A;  3T3K A; 
#chains in the Genus database with same CATH topology
 4HEA 7;  4HS5 A;  1V5R A;  3T3J A;  3SSE A;  2FUG 7;  4EC2 A;  3IMO A;  3IAS 7;  3GD0 A;  2FQL A;  3SSD A;  3SSC A;  3OER A;  3OEQ A;  1EKG A;  4LP1 A;  3T3L A;  2P1X A;  3T3T A;  3I9V 7;  3S5D A;  3A5P A;  1WHZ A;  3IAM 7;  1EW4 A;  3T3X A;  3GD9 A;  4JPD A;  2EFF A;  3S5E A;  4C26 A;  4P78 C;  3S5F A;  2GA5 A;  1D2M A;  3S4M A;  4LK8 A;  1SOY A;  1LY7 A;  3T3K A; 
#chains in the Genus database with same CATH homology
 4HS5 A;  3T3J A;  4EC2 A;  2FQL A;  3OER A;  3OEQ A;  1EKG A;  4LP1 A;  3T3L A;  2P1X A;  3T3T A;  3S5D A;  3T3X A;  1EW4 A;  4JPD A;  2EFF A;  3S5E A;  3S5F A;  2GA5 A;  3S4M A;  4LK8 A;  1SOY A;  1LY7 A;  3T3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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