3T3LA

1.15 a structure of human frataxin variant q153a
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
121
structure length
121
Chain Sequence
LDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKAIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 36
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3lA00
2GA5A 3S5EA 4LK8A 2P1XA 1EW4A 4JPDA 3T3LA 3T3TA 2FQLA 1LY7A 1EKGA 3S5FA 3T3KA 2EFFA 3OERA 3T3XA 1SOYA 4LP1A 3S5DA 4HS5A 3T3JA 3S4MA 3OEQA 4EC2A
chains in the Genus database with same CATH superfamily
2GA5A 1D2MA 3S5EA 4LK8A 1WHZA 2P1XA 1EW4A 3IAS7 4JPDA 3T3LA 1V5RA 3I9V7 3T3TA 3IMOA 3A5PA 2FQLA 1LY7A 3GD0A 1EKGA 3S5FA 3T3KA 2EFFA 3OERA 3T3XA 3SSCA 3GD9A 1SOYA 4P78C 4LP1A 3S5DA 4C26A 4HEA7 4HS5A 3T3JA 3SSEA 3SSDA 2FUG7 3IAM7 3OEQA 3S4MA 4EC2A
chains in the Genus database with same CATH topology
2GA5A 3S5EA 4LK8A 2P1XA 1EW4A 4JPDA 3T3LA 3T3TA 2FQLA 1LY7A 1EKGA 3S5FA 3T3KA 2EFFA 3OERA 3T3XA 1SOYA 4LP1A 3S5DA 4HS5A 3T3JA 3S4MA 3OEQA 4EC2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GA5 A;  3S5E A;  4LK8 A;  2P1X A;  1EW4 A;  4JPD A;  3T3L A;  3T3T A;  2FQL A;  1LY7 A;  1EKG A;  3S5F A;  3T3K A;  2EFF A;  3OER A;  3T3X A;  1SOY A;  4LP1 A;  3S5D A;  4HS5 A;  3T3J A;  3S4M A;  3OEQ A;  4EC2 A; 
#chains in the Genus database with same CATH topology
 2GA5 A;  1D2M A;  3S5E A;  4LK8 A;  1WHZ A;  2P1X A;  1EW4 A;  3IAS 7;  4JPD A;  3T3L A;  1V5R A;  3I9V 7;  3T3T A;  3IMO A;  3A5P A;  2FQL A;  1LY7 A;  3GD0 A;  1EKG A;  3S5F A;  3T3K A;  2EFF A;  3OER A;  3T3X A;  3SSC A;  3GD9 A;  1SOY A;  4P78 C;  4LP1 A;  3S5D A;  4C26 A;  4HEA 7;  4HS5 A;  3T3J A;  3SSE A;  3SSD A;  2FUG 7;  3IAM 7;  3OEQ A;  3S4M A;  4EC2 A; 
#chains in the Genus database with same CATH homology
 2GA5 A;  3S5E A;  4LK8 A;  2P1X A;  1EW4 A;  4JPD A;  3T3L A;  3T3T A;  2FQL A;  1LY7 A;  1EKG A;  3S5F A;  3T3K A;  2EFF A;  3OER A;  3T3X A;  1SOY A;  4LP1 A;  3S5D A;  4HS5 A;  3T3J A;  3S4M A;  3OEQ A;  4EC2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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