3T3XA

1.57 a structure of friedreich's ataxia frataxin variant r165c
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKCYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Frataxin, mitochondrial
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3xA00
3OERA 4EC2A 4JPDA 2GA5A 3T3LA 2FQLA 3S4MA 2EFFA 1EW4A 3T3XA 1LY7A 3OEQA 2P1XA 3T3TA 4LK8A 3S5DA 4LP1A 1SOYA 3T3JA 3S5EA 3S5FA 1EKGA 3T3KA 4HS5A
chains in the Genus database with same CATH superfamily
3IMOA 3I9V7 4P78C 2FUG7 3OERA 4EC2A 3A5PA 4JPDA 2GA5A 3SSDA 1WHZA 3T3LA 2FQLA 3S4MA 1EW4A 2EFFA 3T3XA 1LY7A 3OEQA 2P1XA 1D2MA 3T3TA 3SSEA 4LK8A 3S5DA 3SSCA 1V5RA 4LP1A 1SOYA 3GD0A 3T3JA 4HEA7 3S5EA 3S5FA 3IAS7 1EKGA 3GD9A 3T3KA 4C26A 3IAM7 4HS5A
chains in the Genus database with same CATH topology
3OERA 4EC2A 4JPDA 2GA5A 3T3LA 2FQLA 3S4MA 2EFFA 1EW4A 3T3XA 1LY7A 3OEQA 2P1XA 3T3TA 4LK8A 3S5DA 4LP1A 1SOYA 3T3JA 3S5EA 3S5FA 1EKGA 3T3KA 4HS5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OER A;  4EC2 A;  4JPD A;  2GA5 A;  3T3L A;  2FQL A;  3S4M A;  2EFF A;  1EW4 A;  3T3X A;  1LY7 A;  3OEQ A;  2P1X A;  3T3T A;  4LK8 A;  3S5D A;  4LP1 A;  1SOY A;  3T3J A;  3S5E A;  3S5F A;  1EKG A;  3T3K A;  4HS5 A; 
#chains in the Genus database with same CATH topology
 3IMO A;  3I9V 7;  4P78 C;  2FUG 7;  3OER A;  4EC2 A;  3A5P A;  4JPD A;  2GA5 A;  3SSD A;  1WHZ A;  3T3L A;  2FQL A;  3S4M A;  1EW4 A;  2EFF A;  3T3X A;  1LY7 A;  3OEQ A;  2P1X A;  1D2M A;  3T3T A;  3SSE A;  4LK8 A;  3S5D A;  3SSC A;  1V5R A;  4LP1 A;  1SOY A;  3GD0 A;  3T3J A;  4HEA 7;  3S5E A;  3S5F A;  3IAS 7;  1EKG A;  3GD9 A;  3T3K A;  4C26 A;  3IAM 7;  4HS5 A; 
#chains in the Genus database with same CATH homology
 3OER A;  4EC2 A;  4JPD A;  2GA5 A;  3T3L A;  2FQL A;  3S4M A;  2EFF A;  1EW4 A;  3T3X A;  1LY7 A;  3OEQ A;  2P1X A;  3T3T A;  4LK8 A;  3S5D A;  4LP1 A;  1SOY A;  3T3J A;  3S5E A;  3S5F A;  1EKG A;  3T3K A;  4HS5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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