4IDJA

S.aureus a-hemolysin monomer in complex with fab
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
287
structure length
276
Chain Sequence
IKTGTTDIGSNTTVKTGDLVTYDKENGMLKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin.
pubmed doi rcsb
molecule tags Immune system
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 63
structure length 276
sequence length 287
ec nomenclature
pdb deposition date 2012-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4idjA00
4IYAA 4P1XB 2QK7A 3LKFA 4P1XA 7AHLA 2LKFA 2YGTA 4I0NA 4YHDA 3M4DA 3M2LA 5K59A 3B07B 3ANZA 4P1YB 4IYTA 4IYCA 4P24A 3ROHA 1LKFA 3B07A 4P1YA 4TW1B 3M3RA 4IZLA 4Q7GA 4H56A 2QK7B 4U6VA 1T5RA 3O44A 1PVLA 4IDJA 5K59C 3M4EA 4J0OA 4TW1A
chains in the Genus database with same CATH superfamily
4IYAA 4P1XB 2QK7A 3LKFA 4P1XA 7AHLA 2LKFA 2YGTA 4I0NA 1XEZA 4YHDA 3M4DA 3M2LA 5K59A 3B07B 3ANZA 4P1YB 4IYTA 4IYCA 4P24A 3ROHA 1LKFA 3B07A 4P1YA 4TW1B 3M3RA 4IZLA 4Q7GA 4H56A 2QK7B 4U6VA 1T5RA 3O44A 1PVLA 4IDJA 5K59C 3M4EA 4J0OA 4TW1A
chains in the Genus database with same CATH topology
4IYAA 4P1XB 2QK7A 3LKFA 4P1XA 7AHLA 2LKFA 2YGTA 4I0NA 4YHDA 3M4DA 3M2LA 5K59A 3B07B 3ANZA 4P1YB 4IYTA 4IYCA 4P24A 3ROHA 1LKFA 3B07A 4P1YA 4TW1B 3M3RA 4IZLA 4Q7GA 4H56A 2QK7B 4U6VA 1T5RA 3O44A 1PVLA 4IDJA 5K59C 3M4EA 4J0OA 4TW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IYA A;  4P1X B;  2QK7 A;  3LKF A;  4P1X A;  7AHL A;  2LKF A;  2YGT A;  4I0N A;  4YHD A;  3M4D A;  3M2L A;  5K59 A;  3B07 B;  3ANZ A;  4P1Y B;  4IYT A;  4IYC A;  4P24 A;  3ROH A;  1LKF A;  3B07 A;  4P1Y A;  4TW1 B;  3M3R A;  4IZL A;  4Q7G A;  4H56 A;  2QK7 B;  4U6V A;  1T5R A;  3O44 A;  1PVL A;  4IDJ A;  5K59 C;  3M4E A;  4J0O A;  4TW1 A; 
#chains in the Genus database with same CATH topology
 4IYA A;  4P1X B;  2QK7 A;  3LKF A;  4P1X A;  7AHL A;  2LKF A;  2YGT A;  4I0N A;  1XEZ A;  4YHD A;  3M4D A;  3M2L A;  5K59 A;  3B07 B;  3ANZ A;  4P1Y B;  4IYT A;  4IYC A;  4P24 A;  3ROH A;  1LKF A;  3B07 A;  4P1Y A;  4TW1 B;  3M3R A;  4IZL A;  4Q7G A;  4H56 A;  2QK7 B;  4U6V A;  1T5R A;  3O44 A;  1PVL A;  4IDJ A;  5K59 C;  3M4E A;  4J0O A;  4TW1 A; 
#chains in the Genus database with same CATH homology
 4IYA A;  4P1X B;  2QK7 A;  3LKF A;  4P1X A;  7AHL A;  2LKF A;  2YGT A;  4I0N A;  4YHD A;  3M4D A;  3M2L A;  5K59 A;  3B07 B;  3ANZ A;  4P1Y B;  4IYT A;  4IYC A;  4P24 A;  3ROH A;  1LKF A;  3B07 A;  4P1Y A;  4TW1 B;  3M3R A;  4IZL A;  4Q7G A;  4H56 A;  2QK7 B;  4U6V A;  1T5R A;  3O44 A;  1PVL A;  4IDJ A;  5K59 C;  3M4E A;  4J0O A;  4TW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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