4IDJA

S.aureus a-hemolysin monomer in complex with fab
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
287
structure length
276
Chain Sequence
IKTGTTDIGSNTTVKTGDLVTYDKENGMLKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin.
pubmed doi rcsb
molecule tags Immune system
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 63
structure length 276
sequence length 287
ec nomenclature
pdb deposition date 2012-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4idjA00
2QK7A 4P1XA 3ANZA 4H56A 3ROHA 2YGTA 3M4DA 3LKFA 3M2LA 5K59A 4P1YB 3O44A 1PVLA 5K59C 3B07B 4Q7GA 4TW1B 7AHLA 4IYAA 4IYCA 4IYTA 4YHDA 1LKFA 4P1YA 4IDJA 3B07A 3M3RA 4P1XB 4TW1A 4IZLA 2QK7B 2LKFA 4P24A 3M4EA 4U6VA 1T5RA 4J0OA 4I0NA
chains in the Genus database with same CATH superfamily
2QK7A 4P1XA 3ANZA 4H56A 3ROHA 2YGTA 3M4DA 3LKFA 3M2LA 5K59A 4P1YB 3O44A 1PVLA 5K59C 3B07B 4Q7GA 4TW1B 7AHLA 4IYAA 4IYCA 4IYTA 4YHDA 1LKFA 4P1YA 4IDJA 3B07A 3M3RA 4P1XB 4TW1A 4IZLA 2QK7B 2LKFA 4P24A 3M4EA 4U6VA 1T5RA 1XEZA 4I0NA 4J0OA
chains in the Genus database with same CATH topology
2QK7A 4P1XA 3ANZA 4H56A 3ROHA 2YGTA 3M4DA 3LKFA 3M2LA 5K59A 4P1YB 3O44A 1PVLA 5K59C 3B07B 4Q7GA 4TW1B 7AHLA 4IYAA 4IYCA 4IYTA 4YHDA 1LKFA 4P1YA 4IDJA 3B07A 3M3RA 4P1XB 4TW1A 4IZLA 2QK7B 2LKFA 4P24A 3M4EA 4U6VA 1T5RA 4J0OA 4I0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QK7 A;  4P1X A;  3ANZ A;  4H56 A;  3ROH A;  2YGT A;  3M4D A;  3LKF A;  3M2L A;  5K59 A;  4P1Y B;  3O44 A;  1PVL A;  5K59 C;  3B07 B;  4Q7G A;  4TW1 B;  7AHL A;  4IYA A;  4IYC A;  4IYT A;  4YHD A;  1LKF A;  4P1Y A;  4IDJ A;  3B07 A;  3M3R A;  4P1X B;  4TW1 A;  4IZL A;  2QK7 B;  2LKF A;  4P24 A;  3M4E A;  4U6V A;  1T5R A;  4J0O A;  4I0N A; 
#chains in the Genus database with same CATH topology
 2QK7 A;  4P1X A;  3ANZ A;  4H56 A;  3ROH A;  2YGT A;  3M4D A;  3LKF A;  3M2L A;  5K59 A;  4P1Y B;  3O44 A;  1PVL A;  5K59 C;  3B07 B;  4Q7G A;  4TW1 B;  7AHL A;  4IYA A;  4IYC A;  4IYT A;  4YHD A;  1LKF A;  4P1Y A;  4IDJ A;  3B07 A;  3M3R A;  4P1X B;  4TW1 A;  4IZL A;  2QK7 B;  2LKF A;  4P24 A;  3M4E A;  4U6V A;  1T5R A;  1XEZ A;  4I0N A;  4J0O A; 
#chains in the Genus database with same CATH homology
 2QK7 A;  4P1X A;  3ANZ A;  4H56 A;  3ROH A;  2YGT A;  3M4D A;  3LKF A;  3M2L A;  5K59 A;  4P1Y B;  3O44 A;  1PVL A;  5K59 C;  3B07 B;  4Q7G A;  4TW1 B;  7AHL A;  4IYA A;  4IYC A;  4IYT A;  4YHD A;  1LKF A;  4P1Y A;  4IDJ A;  3B07 A;  3M3R A;  4P1X B;  4TW1 A;  4IZL A;  2QK7 B;  2LKF A;  4P24 A;  3M4E A;  4U6V A;  1T5R A;  4J0O A;  4I0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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