4IYCA

Structure of the t244a mutant of the panton-valentine leucocidin component from staphylococcus aureus
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
283
structure length
277
Chain Sequence
NNIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus phage pvl
molecule keywords LukS-PV
total genus 67
structure length 277
sequence length 283
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4iycA00
3M2LA 2YGTA 3B07B 4P1YA 4H56A 3ANZA 3M4DA 3B07A 4IYCA 4Q7GA 3M3RA 4IYTA 2LKFA 3LKFA 4IYAA 4IZLA 2QK7B 1LKFA 4U6VA 4J0OA 2QK7A 3ROHA 5K59C 4TW1B 7AHLA 3M4EA 1PVLA 1T5RA 4P1XB 4YHDA 4TW1A 5K59A 4IDJA 4I0NA 4P1YB 3O44A 4P1XA 4P24A
chains in the Genus database with same CATH superfamily
3M2LA 2YGTA 3B07B 4P1YA 4H56A 3ANZA 3M4DA 3B07A 4IYCA 4Q7GA 3M3RA 4IYTA 2LKFA 3LKFA 4IYAA 4IZLA 2QK7B 1LKFA 4U6VA 4J0OA 2QK7A 3ROHA 5K59C 4TW1B 7AHLA 1XEZA 3M4EA 1PVLA 1T5RA 4P1XB 4YHDA 4TW1A 5K59A 4IDJA 4I0NA 4P1YB 3O44A 4P1XA 4P24A
chains in the Genus database with same CATH topology
3M2LA 2YGTA 3B07B 4P1YA 4H56A 3ANZA 3M4DA 3B07A 4IYCA 4Q7GA 3M3RA 4IYTA 2LKFA 3LKFA 4IYAA 4IZLA 2QK7B 1LKFA 4U6VA 4J0OA 2QK7A 3ROHA 5K59C 4TW1B 7AHLA 3M4EA 1PVLA 1T5RA 4P1XB 4YHDA 4TW1A 5K59A 4IDJA 4I0NA 4P1YB 3O44A 4P1XA 4P24A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M2L A;  2YGT A;  3B07 B;  4P1Y A;  4H56 A;  3ANZ A;  3M4D A;  3B07 A;  4IYC A;  4Q7G A;  3M3R A;  4IYT A;  2LKF A;  3LKF A;  4IYA A;  4IZL A;  2QK7 B;  1LKF A;  4U6V A;  4J0O A;  2QK7 A;  3ROH A;  5K59 C;  4TW1 B;  7AHL A;  3M4E A;  1PVL A;  1T5R A;  4P1X B;  4YHD A;  4TW1 A;  5K59 A;  4IDJ A;  4I0N A;  4P1Y B;  3O44 A;  4P1X A;  4P24 A; 
#chains in the Genus database with same CATH topology
 3M2L A;  2YGT A;  3B07 B;  4P1Y A;  4H56 A;  3ANZ A;  3M4D A;  3B07 A;  4IYC A;  4Q7G A;  3M3R A;  4IYT A;  2LKF A;  3LKF A;  4IYA A;  4IZL A;  2QK7 B;  1LKF A;  4U6V A;  4J0O A;  2QK7 A;  3ROH A;  5K59 C;  4TW1 B;  7AHL A;  1XEZ A;  3M4E A;  1PVL A;  1T5R A;  4P1X B;  4YHD A;  4TW1 A;  5K59 A;  4IDJ A;  4I0N A;  4P1Y B;  3O44 A;  4P1X A;  4P24 A; 
#chains in the Genus database with same CATH homology
 3M2L A;  2YGT A;  3B07 B;  4P1Y A;  4H56 A;  3ANZ A;  3M4D A;  3B07 A;  4IYC A;  4Q7G A;  3M3R A;  4IYT A;  2LKF A;  3LKF A;  4IYA A;  4IZL A;  2QK7 B;  1LKF A;  4U6V A;  4J0O A;  2QK7 A;  3ROH A;  5K59 C;  4TW1 B;  7AHL A;  3M4E A;  1PVL A;  1T5R A;  4P1X B;  4YHD A;  4TW1 A;  5K59 A;  4IDJ A;  4I0N A;  4P1Y B;  3O44 A;  4P1X A;  4P24 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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