4IYTA

Structure of the y184a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
282
structure length
275
Chain Sequence
NIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPASQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule keywords LukS-PV
molecule tags Toxin
source organism Staphylococcus phage pvl
total genus 70
structure length 275
sequence length 282
ec nomenclature
pdb deposition date 2013-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4iytA00
1PVLA 3LKFA 4IYCA 4TW1A 2YGTA 3B07A 3O44A 4YHDA 3M2LA 4P24A 4Q7GA 4I0NA 3M4DA 4P1YA 2LKFA 4H56A 4IZLA 4P1XB 3M3RA 4U6VA 4IYAA 2QK7B 4J0OA 5K59A 4TW1B 1T5RA 7AHLA 3B07B 1LKFA 4IDJA 3ROHA 4P1YB 4IYTA 5K59C 4P1XA 3M4EA 2QK7A 3ANZA
chains in the Genus database with same CATH superfamily
1PVLA 3LKFA 4IYCA 4TW1A 2YGTA 3B07A 3O44A 4YHDA 3M2LA 4P24A 4Q7GA 4I0NA 3M4DA 4P1YA 2LKFA 4H56A 4IZLA 4P1XB 3M3RA 4U6VA 4IYAA 2QK7B 4J0OA 5K59A 4TW1B 1T5RA 7AHLA 3B07B 1LKFA 4IDJA 3ROHA 4P1YB 1XEZA 4IYTA 5K59C 4P1XA 3M4EA 2QK7A 3ANZA
chains in the Genus database with same CATH topology
1PVLA 3LKFA 4IYCA 4TW1A 2YGTA 3B07A 3O44A 4YHDA 3M2LA 4P24A 4Q7GA 4I0NA 3M4DA 4P1YA 2LKFA 4H56A 4IZLA 4P1XB 3M3RA 4U6VA 4IYAA 2QK7B 4J0OA 5K59A 4TW1B 1T5RA 7AHLA 3B07B 1LKFA 4IDJA 3ROHA 4P1YB 4IYTA 5K59C 4P1XA 3M4EA 2QK7A 3ANZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVL A;  3LKF A;  4IYC A;  4TW1 A;  2YGT A;  3B07 A;  3O44 A;  4YHD A;  3M2L A;  4P24 A;  4Q7G A;  4I0N A;  3M4D A;  4P1Y A;  2LKF A;  4H56 A;  4IZL A;  4P1X B;  3M3R A;  4U6V A;  4IYA A;  2QK7 B;  4J0O A;  5K59 A;  4TW1 B;  1T5R A;  7AHL A;  3B07 B;  1LKF A;  4IDJ A;  3ROH A;  4P1Y B;  4IYT A;  5K59 C;  4P1X A;  3M4E A;  2QK7 A;  3ANZ A; 
#chains in the Genus database with same CATH topology
 1PVL A;  3LKF A;  4IYC A;  4TW1 A;  2YGT A;  3B07 A;  3O44 A;  4YHD A;  3M2L A;  4P24 A;  4Q7G A;  4I0N A;  3M4D A;  4P1Y A;  2LKF A;  4H56 A;  4IZL A;  4P1X B;  3M3R A;  4U6V A;  4IYA A;  2QK7 B;  4J0O A;  5K59 A;  4TW1 B;  1T5R A;  7AHL A;  3B07 B;  1LKF A;  4IDJ A;  3ROH A;  4P1Y B;  1XEZ A;  4IYT A;  5K59 C;  4P1X A;  3M4E A;  2QK7 A;  3ANZ A; 
#chains in the Genus database with same CATH homology
 1PVL A;  3LKF A;  4IYC A;  4TW1 A;  2YGT A;  3B07 A;  3O44 A;  4YHD A;  3M2L A;  4P24 A;  4Q7G A;  4I0N A;  3M4D A;  4P1Y A;  2LKF A;  4H56 A;  4IZL A;  4P1X B;  3M3R A;  4U6V A;  4IYA A;  2QK7 B;  4J0O A;  5K59 A;  4TW1 B;  1T5R A;  7AHL A;  3B07 B;  1LKF A;  4IDJ A;  3ROH A;  4P1Y B;  4IYT A;  5K59 C;  4P1X A;  3M4E A;  2QK7 A;  3ANZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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