4IZLA

Structure of the n248a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
283
structure length
280
Chain Sequence
NNIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPSNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGASYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule keywords LukS-PV
molecule tags Toxin
source organism Staphylococcus phage pvl
total genus 67
structure length 280
sequence length 283
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4izlA00
4P1XA 4P1YA 3O44A 4U6VA 2YGTA 3B07A 2QK7A 7AHLA 4J0OA 4IZLA 4P1YB 1LKFA 4P1XB 4IYCA 3ROHA 1T5RA 3B07B 5K59C 4IYAA 2QK7B 4TW1A 3M3RA 3LKFA 4I0NA 4YHDA 4Q7GA 3ANZA 2LKFA 1PVLA 4IYTA 4P24A 3M2LA 4TW1B 4H56A 3M4DA 5K59A 3M4EA 4IDJA
chains in the Genus database with same CATH superfamily
4P1XA 4P1YA 3O44A 4U6VA 2YGTA 3B07A 2QK7A 7AHLA 4J0OA 4IZLA 4P1YB 1LKFA 4P1XB 4IYCA 3ROHA 1T5RA 3B07B 1XEZA 5K59C 4IYAA 2QK7B 4TW1A 3M3RA 3LKFA 4I0NA 4YHDA 4Q7GA 3ANZA 2LKFA 1PVLA 4IYTA 4P24A 3M2LA 4TW1B 4H56A 3M4DA 5K59A 3M4EA 4IDJA
chains in the Genus database with same CATH topology
4P1XA 4P1YA 3O44A 4U6VA 2YGTA 3B07A 2QK7A 7AHLA 4J0OA 4IZLA 4P1YB 1LKFA 4P1XB 4IYCA 3ROHA 1T5RA 3B07B 5K59C 4IYAA 2QK7B 4TW1A 3M3RA 3LKFA 4I0NA 4YHDA 4Q7GA 3ANZA 2LKFA 1PVLA 4IYTA 4P24A 3M2LA 4TW1B 4H56A 3M4DA 5K59A 3M4EA 4IDJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1X A;  4P1Y A;  3O44 A;  4U6V A;  2YGT A;  3B07 A;  2QK7 A;  7AHL A;  4J0O A;  4IZL A;  4P1Y B;  1LKF A;  4P1X B;  4IYC A;  3ROH A;  1T5R A;  3B07 B;  5K59 C;  4IYA A;  2QK7 B;  4TW1 A;  3M3R A;  3LKF A;  4I0N A;  4YHD A;  4Q7G A;  3ANZ A;  2LKF A;  1PVL A;  4IYT A;  4P24 A;  3M2L A;  4TW1 B;  4H56 A;  3M4D A;  5K59 A;  3M4E A;  4IDJ A; 
#chains in the Genus database with same CATH topology
 4P1X A;  4P1Y A;  3O44 A;  4U6V A;  2YGT A;  3B07 A;  2QK7 A;  7AHL A;  4J0O A;  4IZL A;  4P1Y B;  1LKF A;  4P1X B;  4IYC A;  3ROH A;  1T5R A;  3B07 B;  1XEZ A;  5K59 C;  4IYA A;  2QK7 B;  4TW1 A;  3M3R A;  3LKF A;  4I0N A;  4YHD A;  4Q7G A;  3ANZ A;  2LKF A;  1PVL A;  4IYT A;  4P24 A;  3M2L A;  4TW1 B;  4H56 A;  3M4D A;  5K59 A;  3M4E A;  4IDJ A; 
#chains in the Genus database with same CATH homology
 4P1X A;  4P1Y A;  3O44 A;  4U6V A;  2YGT A;  3B07 A;  2QK7 A;  7AHL A;  4J0O A;  4IZL A;  4P1Y B;  1LKF A;  4P1X B;  4IYC A;  3ROH A;  1T5R A;  3B07 B;  5K59 C;  4IYA A;  2QK7 B;  4TW1 A;  3M3R A;  3LKF A;  4I0N A;  4YHD A;  4Q7G A;  3ANZ A;  2LKF A;  1PVL A;  4IYT A;  4P24 A;  3M2L A;  4TW1 B;  4H56 A;  3M4D A;  5K59 A;  3M4E A;  4IDJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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