4IZLA

Structure of the n248a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
283
structure length
280
Chain Sequence
NNIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPSNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGASYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus phage pvl
molecule keywords LukS-PV
total genus 67
structure length 280
sequence length 283
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4izlA00
4U6VA 3M3RA 3O44A 4IYAA 4IYCA 4Q7GA 3B07B 4H56A 5K59A 4P1YA 3ROHA 4J0OA 4IDJA 2LKFA 2QK7B 3M2LA 4I0NA 3M4DA 3B07A 4TW1B 5K59C 7AHLA 4IZLA 3ANZA 3M4EA 4P1YB 2QK7A 4P1XB 4TW1A 2YGTA 4IYTA 1T5RA 4YHDA 4P1XA 4P24A 1PVLA 1LKFA 3LKFA
chains in the Genus database with same CATH superfamily
4U6VA 3M3RA 3O44A 4IYAA 4IYCA 4Q7GA 3B07B 4H56A 5K59A 4P1YA 3ROHA 4J0OA 4IDJA 2LKFA 2QK7B 3M2LA 4I0NA 3M4DA 3B07A 4TW1B 5K59C 7AHLA 4IZLA 3ANZA 3M4EA 4P1YB 2QK7A 4P1XB 4TW1A 2YGTA 4IYTA 1T5RA 4YHDA 4P1XA 4P24A 1PVLA 1LKFA 1XEZA 3LKFA
chains in the Genus database with same CATH topology
4U6VA 3M3RA 3O44A 4IYAA 4IYCA 4Q7GA 3B07B 4H56A 5K59A 4P1YA 3ROHA 4J0OA 4IDJA 2LKFA 2QK7B 3M2LA 4I0NA 3M4DA 3B07A 4TW1B 5K59C 7AHLA 4IZLA 3ANZA 3M4EA 4P1YB 2QK7A 4P1XB 4TW1A 2YGTA 4IYTA 1T5RA 4YHDA 4P1XA 4P24A 1PVLA 1LKFA 3LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6V A;  3M3R A;  3O44 A;  4IYA A;  4IYC A;  4Q7G A;  3B07 B;  4H56 A;  5K59 A;  4P1Y A;  3ROH A;  4J0O A;  4IDJ A;  2LKF A;  2QK7 B;  3M2L A;  4I0N A;  3M4D A;  3B07 A;  4TW1 B;  5K59 C;  7AHL A;  4IZL A;  3ANZ A;  3M4E A;  4P1Y B;  2QK7 A;  4P1X B;  4TW1 A;  2YGT A;  4IYT A;  1T5R A;  4YHD A;  4P1X A;  4P24 A;  1PVL A;  1LKF A;  3LKF A; 
#chains in the Genus database with same CATH topology
 4U6V A;  3M3R A;  3O44 A;  4IYA A;  4IYC A;  4Q7G A;  3B07 B;  4H56 A;  5K59 A;  4P1Y A;  3ROH A;  4J0O A;  4IDJ A;  2LKF A;  2QK7 B;  3M2L A;  4I0N A;  3M4D A;  3B07 A;  4TW1 B;  5K59 C;  7AHL A;  4IZL A;  3ANZ A;  3M4E A;  4P1Y B;  2QK7 A;  4P1X B;  4TW1 A;  2YGT A;  4IYT A;  1T5R A;  4YHD A;  4P1X A;  4P24 A;  1PVL A;  1LKF A;  1XEZ A;  3LKF A; 
#chains in the Genus database with same CATH homology
 4U6V A;  3M3R A;  3O44 A;  4IYA A;  4IYC A;  4Q7G A;  3B07 B;  4H56 A;  5K59 A;  4P1Y A;  3ROH A;  4J0O A;  4IDJ A;  2LKF A;  2QK7 B;  3M2L A;  4I0N A;  3M4D A;  3B07 A;  4TW1 B;  5K59 C;  7AHL A;  4IZL A;  3ANZ A;  3M4E A;  4P1Y B;  2QK7 A;  4P1X B;  4TW1 A;  2YGT A;  4IYT A;  1T5R A;  4YHD A;  4P1X A;  4P24 A;  1PVL A;  1LKF A;  3LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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