4IZLA

Structure of the n248a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
283
structure length
280
Chain Sequence
NNIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPSNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGASYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule keywords LukS-PV
molecule tags Toxin
source organism Staphylococcus phage pvl
total genus 67
structure length 280
sequence length 283
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4izlA00
4P1YB 3B07A 2QK7B 4P1XA 4P1YA 2QK7A 3M4DA 4IZLA 2LKFA 4I0NA 4IYTA 4IYCA 7AHLA 5K59C 4Q7GA 4U6VA 3LKFA 3M4EA 4YHDA 3O44A 3M2LA 4J0OA 4TW1B 4IYAA 1PVLA 3ANZA 2YGTA 1T5RA 4H56A 4P24A 4TW1A 3M3RA 3B07B 1LKFA 4IDJA 4P1XB 3ROHA 5K59A
chains in the Genus database with same CATH superfamily
4P1YB 3B07A 2QK7B 4P1XA 4P1YA 2QK7A 3M4DA 4IZLA 2LKFA 4I0NA 1XEZA 4IYTA 4IYCA 7AHLA 5K59C 4Q7GA 4U6VA 3LKFA 3M4EA 4YHDA 3O44A 3M2LA 4J0OA 4TW1B 4IYAA 1PVLA 3ANZA 2YGTA 1T5RA 4H56A 4P24A 4TW1A 3M3RA 3B07B 1LKFA 4IDJA 4P1XB 3ROHA 5K59A
chains in the Genus database with same CATH topology
4P1YB 3B07A 2QK7B 4P1XA 4P1YA 2QK7A 3M4DA 4IZLA 2LKFA 4I0NA 4IYTA 4IYCA 7AHLA 5K59C 4Q7GA 4U6VA 3LKFA 3M4EA 4YHDA 3O44A 3M2LA 4J0OA 4TW1B 4IYAA 1PVLA 3ANZA 2YGTA 1T5RA 4H56A 4P24A 4TW1A 3M3RA 3B07B 1LKFA 4IDJA 4P1XB 3ROHA 5K59A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1Y B;  3B07 A;  2QK7 B;  4P1X A;  4P1Y A;  2QK7 A;  3M4D A;  4IZL A;  2LKF A;  4I0N A;  4IYT A;  4IYC A;  7AHL A;  5K59 C;  4Q7G A;  4U6V A;  3LKF A;  3M4E A;  4YHD A;  3O44 A;  3M2L A;  4J0O A;  4TW1 B;  4IYA A;  1PVL A;  3ANZ A;  2YGT A;  1T5R A;  4H56 A;  4P24 A;  4TW1 A;  3M3R A;  3B07 B;  1LKF A;  4IDJ A;  4P1X B;  3ROH A;  5K59 A; 
#chains in the Genus database with same CATH topology
 4P1Y B;  3B07 A;  2QK7 B;  4P1X A;  4P1Y A;  2QK7 A;  3M4D A;  4IZL A;  2LKF A;  4I0N A;  1XEZ A;  4IYT A;  4IYC A;  7AHL A;  5K59 C;  4Q7G A;  4U6V A;  3LKF A;  3M4E A;  4YHD A;  3O44 A;  3M2L A;  4J0O A;  4TW1 B;  4IYA A;  1PVL A;  3ANZ A;  2YGT A;  1T5R A;  4H56 A;  4P24 A;  4TW1 A;  3M3R A;  3B07 B;  1LKF A;  4IDJ A;  4P1X B;  3ROH A;  5K59 A; 
#chains in the Genus database with same CATH homology
 4P1Y B;  3B07 A;  2QK7 B;  4P1X A;  4P1Y A;  2QK7 A;  3M4D A;  4IZL A;  2LKF A;  4I0N A;  4IYT A;  4IYC A;  7AHL A;  5K59 C;  4Q7G A;  4U6V A;  3LKF A;  3M4E A;  4YHD A;  3O44 A;  3M2L A;  4J0O A;  4TW1 B;  4IYA A;  1PVL A;  3ANZ A;  2YGT A;  1T5R A;  4H56 A;  4P24 A;  4TW1 A;  3M3R A;  3B07 B;  1LKF A;  4IDJ A;  4P1X B;  3ROH A;  5K59 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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