4J0OA

Structure of the y246a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
282
structure length
275
Chain Sequence
NIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTAGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule keywords LukS-PV
molecule tags Toxin
source organism Staphylococcus phage pvl
total genus 72
structure length 275
sequence length 282
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4j0oA00
4P24A 4IZLA 3M4EA 1LKFA 5K59C 3B07B 1PVLA 4YHDA 2LKFA 4I0NA 4H56A 4IDJA 4IYAA 3O44A 4P1XA 5K59A 4Q7GA 2YGTA 4P1YA 4IYTA 3M3RA 3ANZA 4P1XB 4TW1A 4P1YB 3ROHA 2QK7A 4U6VA 1T5RA 4IYCA 4TW1B 3M2LA 3M4DA 2QK7B 7AHLA 4J0OA 3LKFA 3B07A
chains in the Genus database with same CATH superfamily
4P24A 4IZLA 3M4EA 1LKFA 5K59C 3B07B 1PVLA 4YHDA 2LKFA 1XEZA 4I0NA 4H56A 4IDJA 4IYAA 3O44A 4P1XA 5K59A 4Q7GA 2YGTA 4P1YA 4IYTA 3M3RA 3ANZA 4P1XB 4TW1A 4P1YB 3ROHA 2QK7A 4U6VA 1T5RA 4IYCA 4TW1B 3M2LA 3M4DA 2QK7B 7AHLA 4J0OA 3LKFA 3B07A
chains in the Genus database with same CATH topology
4P24A 4IZLA 3M4EA 1LKFA 5K59C 3B07B 1PVLA 4YHDA 2LKFA 4I0NA 4H56A 4IDJA 4IYAA 3O44A 4P1XA 5K59A 4Q7GA 2YGTA 4P1YA 4IYTA 3M3RA 3ANZA 4P1XB 4TW1A 4P1YB 3ROHA 2QK7A 4U6VA 1T5RA 4IYCA 4TW1B 3M2LA 3M4DA 2QK7B 7AHLA 4J0OA 3LKFA 3B07A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P24 A;  4IZL A;  3M4E A;  1LKF A;  5K59 C;  3B07 B;  1PVL A;  4YHD A;  2LKF A;  4I0N A;  4H56 A;  4IDJ A;  4IYA A;  3O44 A;  4P1X A;  5K59 A;  4Q7G A;  2YGT A;  4P1Y A;  4IYT A;  3M3R A;  3ANZ A;  4P1X B;  4TW1 A;  4P1Y B;  3ROH A;  2QK7 A;  4U6V A;  1T5R A;  4IYC A;  4TW1 B;  3M2L A;  3M4D A;  2QK7 B;  7AHL A;  4J0O A;  3LKF A;  3B07 A; 
#chains in the Genus database with same CATH topology
 4P24 A;  4IZL A;  3M4E A;  1LKF A;  5K59 C;  3B07 B;  1PVL A;  4YHD A;  2LKF A;  1XEZ A;  4I0N A;  4H56 A;  4IDJ A;  4IYA A;  3O44 A;  4P1X A;  5K59 A;  4Q7G A;  2YGT A;  4P1Y A;  4IYT A;  3M3R A;  3ANZ A;  4P1X B;  4TW1 A;  4P1Y B;  3ROH A;  2QK7 A;  4U6V A;  1T5R A;  4IYC A;  4TW1 B;  3M2L A;  3M4D A;  2QK7 B;  7AHL A;  4J0O A;  3LKF A;  3B07 A; 
#chains in the Genus database with same CATH homology
 4P24 A;  4IZL A;  3M4E A;  1LKF A;  5K59 C;  3B07 B;  1PVL A;  4YHD A;  2LKF A;  4I0N A;  4H56 A;  4IDJ A;  4IYA A;  3O44 A;  4P1X A;  5K59 A;  4Q7G A;  2YGT A;  4P1Y A;  4IYT A;  3M3R A;  3ANZ A;  4P1X B;  4TW1 A;  4P1Y B;  3ROH A;  2QK7 A;  4U6V A;  1T5R A;  4IYC A;  4TW1 B;  3M2L A;  3M4D A;  2QK7 B;  7AHL A;  4J0O A;  3LKF A;  3B07 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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