4J0OA

Structure of the y246a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
282
structure length
275
Chain Sequence
NIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTAGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus phage pvl
molecule keywords LukS-PV
total genus 72
structure length 275
sequence length 282
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4j0oA00
4P1XA 4TW1B 4P24A 2QK7A 4IYCA 4IDJA 3LKFA 4U6VA 4Q7GA 3ANZA 3O44A 4P1YB 3M2LA 4J0OA 4YHDA 4P1XB 4H56A 2YGTA 5K59A 3M4EA 3B07A 1T5RA 2QK7B 3M3RA 1LKFA 4TW1A 4IYTA 3ROHA 1PVLA 4IYAA 3M4DA 4IZLA 4I0NA 5K59C 2LKFA 7AHLA 4P1YA 3B07B
chains in the Genus database with same CATH superfamily
4P1XA 4TW1B 4P24A 2QK7A 4IYCA 4IDJA 3LKFA 4U6VA 4Q7GA 3ANZA 3O44A 4P1YB 3M2LA 4J0OA 4YHDA 4P1XB 4H56A 2YGTA 5K59A 3M4EA 3B07A 1T5RA 2QK7B 3M3RA 1LKFA 4TW1A 4IYTA 3ROHA 1PVLA 4IYAA 3M4DA 4IZLA 4I0NA 5K59C 2LKFA 1XEZA 7AHLA 4P1YA 3B07B
chains in the Genus database with same CATH topology
4P1XA 4TW1B 4P24A 2QK7A 4IYCA 4IDJA 3LKFA 4U6VA 4Q7GA 3ANZA 3O44A 4P1YB 3M2LA 4J0OA 4YHDA 4P1XB 4H56A 2YGTA 5K59A 3M4EA 3B07A 1T5RA 2QK7B 3M3RA 1LKFA 4TW1A 4IYTA 3ROHA 1PVLA 4IYAA 3M4DA 4IZLA 4I0NA 5K59C 2LKFA 7AHLA 4P1YA 3B07B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1X A;  4TW1 B;  4P24 A;  2QK7 A;  4IYC A;  4IDJ A;  3LKF A;  4U6V A;  4Q7G A;  3ANZ A;  3O44 A;  4P1Y B;  3M2L A;  4J0O A;  4YHD A;  4P1X B;  4H56 A;  2YGT A;  5K59 A;  3M4E A;  3B07 A;  1T5R A;  2QK7 B;  3M3R A;  1LKF A;  4TW1 A;  4IYT A;  3ROH A;  1PVL A;  4IYA A;  3M4D A;  4IZL A;  4I0N A;  5K59 C;  2LKF A;  7AHL A;  4P1Y A;  3B07 B; 
#chains in the Genus database with same CATH topology
 4P1X A;  4TW1 B;  4P24 A;  2QK7 A;  4IYC A;  4IDJ A;  3LKF A;  4U6V A;  4Q7G A;  3ANZ A;  3O44 A;  4P1Y B;  3M2L A;  4J0O A;  4YHD A;  4P1X B;  4H56 A;  2YGT A;  5K59 A;  3M4E A;  3B07 A;  1T5R A;  2QK7 B;  3M3R A;  1LKF A;  4TW1 A;  4IYT A;  3ROH A;  1PVL A;  4IYA A;  3M4D A;  4IZL A;  4I0N A;  5K59 C;  2LKF A;  1XEZ A;  7AHL A;  4P1Y A;  3B07 B; 
#chains in the Genus database with same CATH homology
 4P1X A;  4TW1 B;  4P24 A;  2QK7 A;  4IYC A;  4IDJ A;  3LKF A;  4U6V A;  4Q7G A;  3ANZ A;  3O44 A;  4P1Y B;  3M2L A;  4J0O A;  4YHD A;  4P1X B;  4H56 A;  2YGT A;  5K59 A;  3M4E A;  3B07 A;  1T5R A;  2QK7 B;  3M3R A;  1LKF A;  4TW1 A;  4IYT A;  3ROH A;  1PVL A;  4IYA A;  3M4D A;  4IZL A;  4I0N A;  5K59 C;  2LKF A;  7AHL A;  4P1Y A;  3B07 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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