4K6TA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0385
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
186
structure length
186
Chain Sequence
KYDTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein
source organism Human adenovirus 37
publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule keywords Fiber protein
total genus 44
structure length 186
sequence length 186
chains with identical sequence B, C, E, F, G
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6tA00
1KNBA 1QIUA 1UXBA 4K6WA 1NOBA 3EXVA 4ZDGA 1UXAA 3BQ4A 2WSTA 2W9LC 3CNCA 2J2JA 4XQAA 4ATZA 4K6TA 2WGUA 3QNDA 2WBVA 3EXWA 1QHVA 2BZVA 1P69A 1H7ZA 4K6UA 3L89A 1P6AA 2J12A 1UXEA 2J1KC 1KACA 2QLKA 4XQBA 2WGTA 2O39A 3L88A 2BZUA 3F0YA 4WYJA 4LIYA 4XL8A 3O8EA 4K6VA 2WBWA 3N0IA
chains in the Genus database with same CATH superfamily
1KNBA 1QIUA 1UXBA 2JJLA 3ZPFA 2BT7A 4K6WA 1NOBA 3EXVA 1KKEA 1UXAA 4XC5A 3BQ4A 4ZDGA 2WSTA 2W9LC 3CNCA 2J2JA 4XQAA 4ATZA 4K6TA 2WGUA 3QNDA 2VTWA 2BT8A 2IUMA 2WBVA 3EXWA 2VRSA 4GU3A 4D62A 1QHVA 2BZVA 3ZPEA 1P69A 2BSFA 1H7ZA 4K6UA 3L89A 1P6AA 4CW8A 2J12A 1UXEA 2J1KC 1KACA 2QLKA 4XQBA 2WGTA 3S6XA 2O39A 3L88A 2OJ5A 2BZUA 3F0YA 4D63A 4ODBA 4WYJA 4LIYA 2OJ6A 4XL8A 4GU4A 5MHSA 3O8EA 4K6VA 2IUNA 2WBWA 3EOYA 3N0IA
chains in the Genus database with same CATH topology
1KNBA 1QIUA 1UXBA 4K6WA 1NOBA 3EXVA 4ZDGA 1UXAA 3BQ4A 2WSTA 2W9LC 3CNCA 2J2JA 4XQAA 4ATZA 4K6TA 2WGUA 3QNDA 2WBVA 3EXWA 1QHVA 2BZVA 1P69A 1H7ZA 4K6UA 3L89A 1P6AA 2J12A 1UXEA 2J1KC 1KACA 2QLKA 4XQBA 2WGTA 2O39A 3L88A 2BZUA 3F0YA 4WYJA 4LIYA 4XL8A 3O8EA 4K6VA 2WBWA 3N0IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KNB A;  1QIU A;  1UXB A;  4K6W A;  1NOB A;  3EXV A;  4ZDG A;  1UXA A;  3BQ4 A;  2WST A;  2W9L C;  3CNC A;  2J2J A;  4XQA A;  4ATZ A;  4K6T A;  2WGU A;  3QND A;  2WBV A;  3EXW A;  1QHV A;  2BZV A;  1P69 A;  1H7Z A;  4K6U A;  3L89 A;  1P6A A;  2J12 A;  1UXE A;  2J1K C;  1KAC A;  2QLK A;  4XQB A;  2WGT A;  2O39 A;  3L88 A;  2BZU A;  3F0Y A;  4WYJ A;  4LIY A;  4XL8 A;  3O8E A;  4K6V A;  2WBW A;  3N0I A; 
#chains in the Genus database with same CATH topology
 1KNB A;  1QIU A;  1UXB A;  2JJL A;  3ZPF A;  2BT7 A;  4K6W A;  1NOB A;  3EXV A;  1KKE A;  1UXA A;  4XC5 A;  3BQ4 A;  4ZDG A;  2WST A;  2W9L C;  3CNC A;  2J2J A;  4XQA A;  4ATZ A;  4K6T A;  2WGU A;  3QND A;  2VTW A;  2BT8 A;  2IUM A;  2WBV A;  3EXW A;  2VRS A;  4GU3 A;  4D62 A;  1QHV A;  2BZV A;  3ZPE A;  1P69 A;  2BSF A;  1H7Z A;  4K6U A;  3L89 A;  1P6A A;  4CW8 A;  2J12 A;  1UXE A;  2J1K C;  1KAC A;  2QLK A;  4XQB A;  2WGT A;  3S6X A;  2O39 A;  3L88 A;  2OJ5 A;  2BZU A;  3F0Y A;  4D63 A;  4ODB A;  4WYJ A;  4LIY A;  2OJ6 A;  4XL8 A;  4GU4 A;  5MHS A;  3O8E A;  4K6V A;  2IUN A;  2WBW A;  3EOY A;  3N0I A; 
#chains in the Genus database with same CATH homology
 1KNB A;  1QIU A;  1UXB A;  4K6W A;  1NOB A;  3EXV A;  4ZDG A;  1UXA A;  3BQ4 A;  2WST A;  2W9L C;  3CNC A;  2J2J A;  4XQA A;  4ATZ A;  4K6T A;  2WGU A;  3QND A;  2WBV A;  3EXW A;  1QHV A;  2BZV A;  1P69 A;  1H7Z A;  4K6U A;  3L89 A;  1P6A A;  2J12 A;  1UXE A;  2J1K C;  1KAC A;  2QLK A;  4XQB A;  2WGT A;  2O39 A;  3L88 A;  2BZU A;  3F0Y A;  4WYJ A;  4LIY A;  4XL8 A;  3O8E A;  4K6V A;  2WBW A;  3N0I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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