4K6VA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0407
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
184
structure length
184
Chain Sequence
DTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber protein
total genus 45
structure length 184
sequence length 184
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6vA00
2J2JA 3CNCA 1QHVA 4XQBA 2WBWA 2O39A 1QIUA 3F0YA 4LIYA 4K6UA 3EXVA 2WGUA 2J12A 1P6AA 1UXBA 2J1KC 1KACA 3N0IA 3O8EA 4XL8A 3L88A 4K6TA 1UXEA 2QLKA 2W9LC 4K6WA 2WSTA 1NOBA 3EXWA 4ZDGA 2WGTA 4ATZA 4K6VA 4XQAA 1H7ZA 1KNBA 1UXAA 2BZVA 3BQ4A 3L89A 3QNDA 4WYJA 2BZUA 1P69A 2WBVA
chains in the Genus database with same CATH superfamily
2J2JA 3CNCA 1QHVA 4XQBA 2WBWA 2O39A 1QIUA 4CW8A 4D63A 2BT8A 3F0YA 3EOYA 4LIYA 4K6UA 3EXVA 3ZPEA 2WGUA 2J12A 1P6AA 4XC5A 1UXBA 2J1KC 1KACA 3N0IA 3O8EA 4XL8A 3L88A 2OJ5A 2VTWA 2BSFA 4K6TA 4GU4A 1UXEA 3ZPFA 2QLKA 2VRSA 2BT7A 2W9LC 4K6WA 2WSTA 3S6XA 1NOBA 1KKEA 4ODBA 3EXWA 4ZDGA 2WGTA 4D62A 4ATZA 4K6VA 2JJLA 4XQAA 1H7ZA 1KNBA 5MHSA 1UXAA 2BZVA 3BQ4A 2IUMA 2OJ6A 3L89A 2BZUA 3QNDA 4WYJA 2IUNA 1P69A 2WBVA 4GU3A
chains in the Genus database with same CATH topology
2J2JA 3CNCA 1QHVA 4XQBA 2WBWA 2O39A 1QIUA 3F0YA 4LIYA 4K6UA 3EXVA 2WGUA 2J12A 1P6AA 1UXBA 2J1KC 1KACA 3N0IA 3O8EA 4XL8A 3L88A 4K6TA 1UXEA 2QLKA 2W9LC 4K6WA 2WSTA 1NOBA 3EXWA 4ZDGA 2WGTA 4ATZA 4K6VA 4XQAA 1H7ZA 1KNBA 1UXAA 2BZVA 3BQ4A 3L89A 3QNDA 4WYJA 2BZUA 1P69A 2WBVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J2J A;  3CNC A;  1QHV A;  4XQB A;  2WBW A;  2O39 A;  1QIU A;  3F0Y A;  4LIY A;  4K6U A;  3EXV A;  2WGU A;  2J12 A;  1P6A A;  1UXB A;  2J1K C;  1KAC A;  3N0I A;  3O8E A;  4XL8 A;  3L88 A;  4K6T A;  1UXE A;  2QLK A;  2W9L C;  4K6W A;  2WST A;  1NOB A;  3EXW A;  4ZDG A;  2WGT A;  4ATZ A;  4K6V A;  4XQA A;  1H7Z A;  1KNB A;  1UXA A;  2BZV A;  3BQ4 A;  3L89 A;  3QND A;  4WYJ A;  2BZU A;  1P69 A;  2WBV A; 
#chains in the Genus database with same CATH topology
 2J2J A;  3CNC A;  1QHV A;  4XQB A;  2WBW A;  2O39 A;  1QIU A;  4CW8 A;  4D63 A;  2BT8 A;  3F0Y A;  3EOY A;  4LIY A;  4K6U A;  3EXV A;  3ZPE A;  2WGU A;  2J12 A;  1P6A A;  4XC5 A;  1UXB A;  2J1K C;  1KAC A;  3N0I A;  3O8E A;  4XL8 A;  3L88 A;  2OJ5 A;  2VTW A;  2BSF A;  4K6T A;  4GU4 A;  1UXE A;  3ZPF A;  2QLK A;  2VRS A;  2BT7 A;  2W9L C;  4K6W A;  2WST A;  3S6X A;  1NOB A;  1KKE A;  4ODB A;  3EXW A;  4ZDG A;  2WGT A;  4D62 A;  4ATZ A;  4K6V A;  2JJL A;  4XQA A;  1H7Z A;  1KNB A;  5MHS A;  1UXA A;  2BZV A;  3BQ4 A;  2IUM A;  2OJ6 A;  3L89 A;  2BZU A;  3QND A;  4WYJ A;  2IUN A;  1P69 A;  2WBV A;  4GU3 A; 
#chains in the Genus database with same CATH homology
 2J2J A;  3CNC A;  1QHV A;  4XQB A;  2WBW A;  2O39 A;  1QIU A;  3F0Y A;  4LIY A;  4K6U A;  3EXV A;  2WGU A;  2J12 A;  1P6A A;  1UXB A;  2J1K C;  1KAC A;  3N0I A;  3O8E A;  4XL8 A;  3L88 A;  4K6T A;  1UXE A;  2QLK A;  2W9L C;  4K6W A;  2WST A;  1NOB A;  3EXW A;  4ZDG A;  2WGT A;  4ATZ A;  4K6V A;  4XQA A;  1H7Z A;  1KNB A;  1UXA A;  2BZV A;  3BQ4 A;  3L89 A;  3QND A;  4WYJ A;  2BZU A;  1P69 A;  2WBV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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