4K6WA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0408
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
183
structure length
183
Chain Sequence
TRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber protein
total genus 42
structure length 183
sequence length 183
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6wA00
3F0YA 2WGUA 4XQAA 1NOBA 4XL8A 1H7ZA 2J12A 4K6WA 3EXWA 2BZUA 2W9LC 3L89A 4ZDGA 4K6VA 2QLKA 2J1KC 1KACA 1UXAA 3CNCA 1P6AA 2WBVA 1QIUA 4K6UA 2WBWA 2WSTA 4LIYA 1UXEA 1KNBA 2WGTA 3BQ4A 3N0IA 4ATZA 4WYJA 1UXBA 3EXVA 3L88A 4XQBA 1P69A 4K6TA 2J2JA 2O39A 2BZVA 3O8EA 3QNDA 1QHVA
chains in the Genus database with same CATH superfamily
2IUNA 3F0YA 2WGUA 4XQAA 1NOBA 4XL8A 1H7ZA 4GU4A 2J12A 4K6WA 2IUMA 3EXWA 2BZUA 2W9LC 4GU3A 4XC5A 3L89A 2JJLA 3ZPFA 1KKEA 4ZDGA 3S6XA 4ODBA 4K6VA 4CW8A 2QLKA 2J1KC 1KACA 1UXAA 2BT7A 3EOYA 3CNCA 1P6AA 3ZPEA 2WBVA 1QIUA 4K6UA 2WBWA 2WSTA 2VTWA 4LIYA 1UXEA 1KNBA 2WGTA 3BQ4A 3N0IA 5MHSA 4D62A 4ATZA 4WYJA 1UXBA 3EXVA 3L88A 4XQBA 4D63A 2OJ6A 1P69A 4K6TA 2BSFA 2VRSA 2J2JA 2OJ5A 2O39A 2BZVA 3O8EA 2BT8A 3QNDA 1QHVA
chains in the Genus database with same CATH topology
3F0YA 2WGUA 4XQAA 1NOBA 4XL8A 1H7ZA 2J12A 4K6WA 3EXWA 2BZUA 2W9LC 3L89A 4ZDGA 4K6VA 2QLKA 2J1KC 1KACA 1UXAA 3CNCA 1P6AA 2WBVA 1QIUA 4K6UA 2WBWA 2WSTA 4LIYA 1UXEA 1KNBA 2WGTA 3BQ4A 3N0IA 4ATZA 4WYJA 1UXBA 3EXVA 3L88A 4XQBA 1P69A 4K6TA 2J2JA 2O39A 2BZVA 3O8EA 3QNDA 1QHVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F0Y A;  2WGU A;  4XQA A;  1NOB A;  4XL8 A;  1H7Z A;  2J12 A;  4K6W A;  3EXW A;  2BZU A;  2W9L C;  3L89 A;  4ZDG A;  4K6V A;  2QLK A;  2J1K C;  1KAC A;  1UXA A;  3CNC A;  1P6A A;  2WBV A;  1QIU A;  4K6U A;  2WBW A;  2WST A;  4LIY A;  1UXE A;  1KNB A;  2WGT A;  3BQ4 A;  3N0I A;  4ATZ A;  4WYJ A;  1UXB A;  3EXV A;  3L88 A;  4XQB A;  1P69 A;  4K6T A;  2J2J A;  2O39 A;  2BZV A;  3O8E A;  3QND A;  1QHV A; 
#chains in the Genus database with same CATH topology
 2IUN A;  3F0Y A;  2WGU A;  4XQA A;  1NOB A;  4XL8 A;  1H7Z A;  4GU4 A;  2J12 A;  4K6W A;  2IUM A;  3EXW A;  2BZU A;  2W9L C;  4GU3 A;  4XC5 A;  3L89 A;  2JJL A;  3ZPF A;  1KKE A;  4ZDG A;  3S6X A;  4ODB A;  4K6V A;  4CW8 A;  2QLK A;  2J1K C;  1KAC A;  1UXA A;  2BT7 A;  3EOY A;  3CNC A;  1P6A A;  3ZPE A;  2WBV A;  1QIU A;  4K6U A;  2WBW A;  2WST A;  2VTW A;  4LIY A;  1UXE A;  1KNB A;  2WGT A;  3BQ4 A;  3N0I A;  5MHS A;  4D62 A;  4ATZ A;  4WYJ A;  1UXB A;  3EXV A;  3L88 A;  4XQB A;  4D63 A;  2OJ6 A;  1P69 A;  4K6T A;  2BSF A;  2VRS A;  2J2J A;  2OJ5 A;  2O39 A;  2BZV A;  3O8E A;  2BT8 A;  3QND A;  1QHV A; 
#chains in the Genus database with same CATH homology
 3F0Y A;  2WGU A;  4XQA A;  1NOB A;  4XL8 A;  1H7Z A;  2J12 A;  4K6W A;  3EXW A;  2BZU A;  2W9L C;  3L89 A;  4ZDG A;  4K6V A;  2QLK A;  2J1K C;  1KAC A;  1UXA A;  3CNC A;  1P6A A;  2WBV A;  1QIU A;  4K6U A;  2WBW A;  2WST A;  4LIY A;  1UXE A;  1KNB A;  2WGT A;  3BQ4 A;  3N0I A;  4ATZ A;  4WYJ A;  1UXB A;  3EXV A;  3L88 A;  4XQB A;  1P69 A;  4K6T A;  2J2J A;  2O39 A;  2BZV A;  3O8E A;  3QND A;  1QHV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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