4K6WA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0408
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
183
structure length
183
Chain Sequence
TRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber protein
total genus 42
structure length 183
sequence length 183
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4k6wA00
3L89A 2J2JA 2WBVA 1KACA 3EXWA 3EXVA 2BZUA 1P69A 3L88A 4K6WA 2J12A 4K6TA 1UXBA 4XL8A 4K6VA 4LIYA 2W9LC 1H7ZA 4WYJA 1KNBA 3N0IA 4ATZA 1QHVA 2WSTA 4ZDGA 4K6UA 3BQ4A 4XQBA 1QIUA 3F0YA 4XQAA 2O39A 2J1KC 2QLKA 3O8EA 2WBWA 1P6AA 3QNDA 1UXAA 3CNCA 2WGTA 2BZVA 1UXEA 2WGUA 1NOBA
chains in the Genus database with same CATH superfamily
3L89A 2VRSA 2J2JA 2WBVA 1KACA 3EXWA 3EXVA 4GU4A 2BZUA 2BT7A 1P69A 2BT8A 3L88A 2BSFA 4K6WA 1KKEA 2JJLA 2J12A 2OJ6A 4K6TA 1UXBA 4ODBA 4XL8A 4K6VA 4D62A 4LIYA 2W9LC 3EOYA 1H7ZA 4WYJA 1KNBA 3N0IA 4ATZA 3ZPFA 1QHVA 2WSTA 4ZDGA 2OJ5A 4K6UA 3BQ4A 4XQBA 1QIUA 2IUMA 4GU3A 3F0YA 4XQAA 3ZPEA 4CW8A 2O39A 2J1KC 2QLKA 4XC5A 4D63A 3O8EA 2WBWA 5MHSA 1P6AA 3QNDA 3S6XA 1UXAA 3CNCA 2WGTA 2BZVA 1UXEA 2VTWA 2IUNA 2WGUA 1NOBA
chains in the Genus database with same CATH topology
3L89A 2J2JA 2WBVA 1KACA 3EXWA 3EXVA 2BZUA 1P69A 3L88A 4K6WA 2J12A 4K6TA 1UXBA 4XL8A 4K6VA 4LIYA 2W9LC 1H7ZA 4WYJA 1KNBA 3N0IA 4ATZA 1QHVA 2WSTA 4ZDGA 4K6UA 3BQ4A 4XQBA 1QIUA 3F0YA 4XQAA 2O39A 2J1KC 2QLKA 3O8EA 2WBWA 1P6AA 3QNDA 1UXAA 3CNCA 2WGTA 2BZVA 1UXEA 2WGUA 1NOBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L89 A;  2J2J A;  2WBV A;  1KAC A;  3EXW A;  3EXV A;  2BZU A;  1P69 A;  3L88 A;  4K6W A;  2J12 A;  4K6T A;  1UXB A;  4XL8 A;  4K6V A;  4LIY A;  2W9L C;  1H7Z A;  4WYJ A;  1KNB A;  3N0I A;  4ATZ A;  1QHV A;  2WST A;  4ZDG A;  4K6U A;  3BQ4 A;  4XQB A;  1QIU A;  3F0Y A;  4XQA A;  2O39 A;  2J1K C;  2QLK A;  3O8E A;  2WBW A;  1P6A A;  3QND A;  1UXA A;  3CNC A;  2WGT A;  2BZV A;  1UXE A;  2WGU A;  1NOB A; 
#chains in the Genus database with same CATH topology
 3L89 A;  2VRS A;  2J2J A;  2WBV A;  1KAC A;  3EXW A;  3EXV A;  4GU4 A;  2BZU A;  2BT7 A;  1P69 A;  2BT8 A;  3L88 A;  2BSF A;  4K6W A;  1KKE A;  2JJL A;  2J12 A;  2OJ6 A;  4K6T A;  1UXB A;  4ODB A;  4XL8 A;  4K6V A;  4D62 A;  4LIY A;  2W9L C;  3EOY A;  1H7Z A;  4WYJ A;  1KNB A;  3N0I A;  4ATZ A;  3ZPF A;  1QHV A;  2WST A;  4ZDG A;  2OJ5 A;  4K6U A;  3BQ4 A;  4XQB A;  1QIU A;  2IUM A;  4GU3 A;  3F0Y A;  4XQA A;  3ZPE A;  4CW8 A;  2O39 A;  2J1K C;  2QLK A;  4XC5 A;  4D63 A;  3O8E A;  2WBW A;  5MHS A;  1P6A A;  3QND A;  3S6X A;  1UXA A;  3CNC A;  2WGT A;  2BZV A;  1UXE A;  2VTW A;  2IUN A;  2WGU A;  1NOB A; 
#chains in the Genus database with same CATH homology
 3L89 A;  2J2J A;  2WBV A;  1KAC A;  3EXW A;  3EXV A;  2BZU A;  1P69 A;  3L88 A;  4K6W A;  2J12 A;  4K6T A;  1UXB A;  4XL8 A;  4K6V A;  4LIY A;  2W9L C;  1H7Z A;  4WYJ A;  1KNB A;  3N0I A;  4ATZ A;  1QHV A;  2WST A;  4ZDG A;  4K6U A;  3BQ4 A;  4XQB A;  1QIU A;  3F0Y A;  4XQA A;  2O39 A;  2J1K C;  2QLK A;  3O8E A;  2WBW A;  1P6A A;  3QND A;  1UXA A;  3CNC A;  2WGT A;  2BZV A;  1UXE A;  2WGU A;  1NOB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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