4P1YB

Crystal structure of staphylococcal gamma-hemolysin prepore
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
275
structure length
264
Chain Sequence
DIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of transmembrane beta-barrel formation of staphylococcal pore-forming toxins.
pubmed doi rcsb
molecule keywords Gamma-hemolysin component B
molecule tags Toxin
source organism Staphylococcus aureus
total genus 59
structure length 264
sequence length 275
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2014-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4p1yB00
4P24A 2LKFA 4U6VA 3O44A 4IYAA 2YGTA 1T5RA 5K59A 5K59C 3M2LA 3ANZA 4P1YA 1LKFA 2QK7B 3M4DA 4TW1B 3M3RA 4H56A 4P1XA 3B07A 4IDJA 3ROHA 3LKFA 3M4EA 7AHLA 4IYTA 4Q7GA 4J0OA 1PVLA 4IYCA 2QK7A 4TW1A 4P1YB 4YHDA 4I0NA 4P1XB 3B07B 4IZLA
chains in the Genus database with same CATH superfamily
4P24A 2LKFA 4U6VA 3O44A 4IYAA 2YGTA 1T5RA 1XEZA 5K59A 5K59C 3M2LA 3ANZA 4P1YA 1LKFA 2QK7B 3M4DA 4TW1B 3M3RA 4H56A 4P1XA 3B07A 4IDJA 3ROHA 3LKFA 3M4EA 7AHLA 4IYTA 4Q7GA 4J0OA 1PVLA 4IYCA 2QK7A 4TW1A 4P1YB 4YHDA 4I0NA 4P1XB 3B07B 4IZLA
chains in the Genus database with same CATH topology
4P24A 2LKFA 4U6VA 3O44A 4IYAA 2YGTA 1T5RA 5K59A 5K59C 3M2LA 3ANZA 4P1YA 1LKFA 2QK7B 3M4DA 4TW1B 3M3RA 4H56A 4P1XA 3B07A 4IDJA 3ROHA 3LKFA 3M4EA 7AHLA 4IYTA 4Q7GA 4J0OA 1PVLA 4IYCA 2QK7A 4TW1A 4P1YB 4YHDA 4I0NA 4P1XB 3B07B 4IZLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P24 A;  2LKF A;  4U6V A;  3O44 A;  4IYA A;  2YGT A;  1T5R A;  5K59 A;  5K59 C;  3M2L A;  3ANZ A;  4P1Y A;  1LKF A;  2QK7 B;  3M4D A;  4TW1 B;  3M3R A;  4H56 A;  4P1X A;  3B07 A;  4IDJ A;  3ROH A;  3LKF A;  3M4E A;  7AHL A;  4IYT A;  4Q7G A;  4J0O A;  1PVL A;  4IYC A;  2QK7 A;  4TW1 A;  4P1Y B;  4YHD A;  4I0N A;  4P1X B;  3B07 B;  4IZL A; 
#chains in the Genus database with same CATH topology
 4P24 A;  2LKF A;  4U6V A;  3O44 A;  4IYA A;  2YGT A;  1T5R A;  1XEZ A;  5K59 A;  5K59 C;  3M2L A;  3ANZ A;  4P1Y A;  1LKF A;  2QK7 B;  3M4D A;  4TW1 B;  3M3R A;  4H56 A;  4P1X A;  3B07 A;  4IDJ A;  3ROH A;  3LKF A;  3M4E A;  7AHL A;  4IYT A;  4Q7G A;  4J0O A;  1PVL A;  4IYC A;  2QK7 A;  4TW1 A;  4P1Y B;  4YHD A;  4I0N A;  4P1X B;  3B07 B;  4IZL A; 
#chains in the Genus database with same CATH homology
 4P24 A;  2LKF A;  4U6V A;  3O44 A;  4IYA A;  2YGT A;  1T5R A;  5K59 A;  5K59 C;  3M2L A;  3ANZ A;  4P1Y A;  1LKF A;  2QK7 B;  3M4D A;  4TW1 B;  3M3R A;  4H56 A;  4P1X A;  3B07 A;  4IDJ A;  3ROH A;  3LKF A;  3M4E A;  7AHL A;  4IYT A;  4Q7G A;  4J0O A;  1PVL A;  4IYC A;  2QK7 A;  4TW1 A;  4P1Y B;  4YHD A;  4I0N A;  4P1X B;  3B07 B;  4IZL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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