4TW1A

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
290
structure length
281
Chain Sequence
GDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLND
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus aureus
molecule keywords Possible leukocidin subunit
total genus 59
structure length 281
sequence length 290
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1A00
3M4DA 1PVLA 3B07B 3ANZA 4J0OA 4IYTA 2YGTA 4YHDA 4P24A 4P1YA 4U6VA 3M3RA 4IZLA 5K59C 4Q7GA 4P1YB 7AHLA 4IDJA 3M2LA 5K59A 3O44A 1LKFA 4I0NA 2LKFA 1T5RA 4IYAA 3ROHA 4TW1A 4IYCA 2QK7A 3M4EA 4P1XA 4TW1B 2QK7B 4H56A 3B07A 4P1XB 3LKFA
chains in the Genus database with same CATH superfamily
3M4DA 1PVLA 3B07B 3ANZA 4J0OA 4IYTA 2YGTA 4YHDA 4P24A 4P1YA 4U6VA 3M3RA 4IZLA 5K59C 4Q7GA 4P1YB 7AHLA 4IDJA 3M2LA 5K59A 3O44A 1LKFA 4I0NA 2LKFA 1T5RA 1XEZA 4IYAA 3ROHA 4TW1A 4IYCA 2QK7A 3M4EA 4P1XA 4TW1B 2QK7B 4H56A 3B07A 4P1XB 3LKFA
chains in the Genus database with same CATH topology
3M4DA 1PVLA 3B07B 3ANZA 4J0OA 4IYTA 2YGTA 4YHDA 4P24A 4P1YA 4U6VA 3M3RA 4IZLA 5K59C 4Q7GA 4P1YB 7AHLA 4IDJA 3M2LA 5K59A 3O44A 1LKFA 4I0NA 2LKFA 1T5RA 4IYAA 3ROHA 4TW1A 4IYCA 2QK7A 3M4EA 4P1XA 4TW1B 2QK7B 4H56A 3B07A 4P1XB 3LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M4D A;  1PVL A;  3B07 B;  3ANZ A;  4J0O A;  4IYT A;  2YGT A;  4YHD A;  4P24 A;  4P1Y A;  4U6V A;  3M3R A;  4IZL A;  5K59 C;  4Q7G A;  4P1Y B;  7AHL A;  4IDJ A;  3M2L A;  5K59 A;  3O44 A;  1LKF A;  4I0N A;  2LKF A;  1T5R A;  4IYA A;  3ROH A;  4TW1 A;  4IYC A;  2QK7 A;  3M4E A;  4P1X A;  4TW1 B;  2QK7 B;  4H56 A;  3B07 A;  4P1X B;  3LKF A; 
#chains in the Genus database with same CATH topology
 3M4D A;  1PVL A;  3B07 B;  3ANZ A;  4J0O A;  4IYT A;  2YGT A;  4YHD A;  4P24 A;  4P1Y A;  4U6V A;  3M3R A;  4IZL A;  5K59 C;  4Q7G A;  4P1Y B;  7AHL A;  4IDJ A;  3M2L A;  5K59 A;  3O44 A;  1LKF A;  4I0N A;  2LKF A;  1T5R A;  1XEZ A;  4IYA A;  3ROH A;  4TW1 A;  4IYC A;  2QK7 A;  3M4E A;  4P1X A;  4TW1 B;  2QK7 B;  4H56 A;  3B07 A;  4P1X B;  3LKF A; 
#chains in the Genus database with same CATH homology
 3M4D A;  1PVL A;  3B07 B;  3ANZ A;  4J0O A;  4IYT A;  2YGT A;  4YHD A;  4P24 A;  4P1Y A;  4U6V A;  3M3R A;  4IZL A;  5K59 C;  4Q7G A;  4P1Y B;  7AHL A;  4IDJ A;  3M2L A;  5K59 A;  3O44 A;  1LKF A;  4I0N A;  2LKF A;  1T5R A;  4IYA A;  3ROH A;  4TW1 A;  4IYC A;  2QK7 A;  3M4E A;  4P1X A;  4TW1 B;  2QK7 B;  4H56 A;  3B07 A;  4P1X B;  3LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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