4TW1B

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
289
structure length
282
Chain Sequence
TAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus aureus
molecule keywords Possible leukocidin subunit
total genus 63
structure length 282
sequence length 289
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1B00
3M2LA 2YGTA 3B07B 4P1YA 4H56A 3ANZA 3M4DA 3B07A 4IYCA 4Q7GA 3M3RA 4IYTA 2LKFA 3LKFA 4IYAA 4IZLA 2QK7B 1LKFA 4U6VA 4J0OA 2QK7A 3ROHA 5K59C 4TW1B 7AHLA 3M4EA 1PVLA 1T5RA 4P1XB 4YHDA 4TW1A 5K59A 4IDJA 4I0NA 4P1YB 3O44A 4P1XA 4P24A
chains in the Genus database with same CATH superfamily
3M2LA 2YGTA 3B07B 4P1YA 4H56A 3ANZA 3M4DA 3B07A 4IYCA 4Q7GA 3M3RA 4IYTA 2LKFA 3LKFA 4IYAA 4IZLA 2QK7B 1LKFA 4U6VA 4J0OA 2QK7A 3ROHA 5K59C 4TW1B 7AHLA 1XEZA 3M4EA 1PVLA 1T5RA 4P1XB 4YHDA 4TW1A 5K59A 4IDJA 4I0NA 4P1YB 3O44A 4P1XA 4P24A
chains in the Genus database with same CATH topology
3M2LA 2YGTA 3B07B 4P1YA 4H56A 3ANZA 3M4DA 3B07A 4IYCA 4Q7GA 3M3RA 4IYTA 2LKFA 3LKFA 4IYAA 4IZLA 2QK7B 1LKFA 4U6VA 4J0OA 2QK7A 3ROHA 5K59C 4TW1B 7AHLA 3M4EA 1PVLA 1T5RA 4P1XB 4YHDA 4TW1A 5K59A 4IDJA 4I0NA 4P1YB 3O44A 4P1XA 4P24A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M2L A;  2YGT A;  3B07 B;  4P1Y A;  4H56 A;  3ANZ A;  3M4D A;  3B07 A;  4IYC A;  4Q7G A;  3M3R A;  4IYT A;  2LKF A;  3LKF A;  4IYA A;  4IZL A;  2QK7 B;  1LKF A;  4U6V A;  4J0O A;  2QK7 A;  3ROH A;  5K59 C;  4TW1 B;  7AHL A;  3M4E A;  1PVL A;  1T5R A;  4P1X B;  4YHD A;  4TW1 A;  5K59 A;  4IDJ A;  4I0N A;  4P1Y B;  3O44 A;  4P1X A;  4P24 A; 
#chains in the Genus database with same CATH topology
 3M2L A;  2YGT A;  3B07 B;  4P1Y A;  4H56 A;  3ANZ A;  3M4D A;  3B07 A;  4IYC A;  4Q7G A;  3M3R A;  4IYT A;  2LKF A;  3LKF A;  4IYA A;  4IZL A;  2QK7 B;  1LKF A;  4U6V A;  4J0O A;  2QK7 A;  3ROH A;  5K59 C;  4TW1 B;  7AHL A;  1XEZ A;  3M4E A;  1PVL A;  1T5R A;  4P1X B;  4YHD A;  4TW1 A;  5K59 A;  4IDJ A;  4I0N A;  4P1Y B;  3O44 A;  4P1X A;  4P24 A; 
#chains in the Genus database with same CATH homology
 3M2L A;  2YGT A;  3B07 B;  4P1Y A;  4H56 A;  3ANZ A;  3M4D A;  3B07 A;  4IYC A;  4Q7G A;  3M3R A;  4IYT A;  2LKF A;  3LKF A;  4IYA A;  4IZL A;  2QK7 B;  1LKF A;  4U6V A;  4J0O A;  2QK7 A;  3ROH A;  5K59 C;  4TW1 B;  7AHL A;  3M4E A;  1PVL A;  1T5R A;  4P1X B;  4YHD A;  4TW1 A;  5K59 A;  4IDJ A;  4I0N A;  4P1Y B;  3O44 A;  4P1X A;  4P24 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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