4TW1B

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
289
structure length
282
Chain Sequence
TAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
molecule keywords Possible leukocidin subunit
molecule tags Toxin
source organism Staphylococcus aureus
total genus 63
structure length 282
sequence length 289
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1B00
4TW1A 4U6VA 4P1XA 4YHDA 3M3RA 2LKFA 4P1YB 3M4DA 3B07A 3ANZA 7AHLA 1T5RA 4TW1B 4IYTA 4P1XB 5K59A 2YGTA 3ROHA 1LKFA 4IYCA 3M2LA 4H56A 4IDJA 4Q7GA 3B07B 4IYAA 2QK7A 3M4EA 4IZLA 4J0OA 4P24A 2QK7B 4P1YA 3O44A 1PVLA 4I0NA 5K59C 3LKFA
chains in the Genus database with same CATH superfamily
4TW1A 4U6VA 4P1XA 4YHDA 3M3RA 2LKFA 4P1YB 3M4DA 3B07A 3ANZA 7AHLA 1T5RA 4TW1B 4IYTA 4P1XB 5K59A 2YGTA 3ROHA 1LKFA 4IYCA 1XEZA 3M2LA 4H56A 4IDJA 4Q7GA 3B07B 4IYAA 2QK7A 3M4EA 4IZLA 4J0OA 4P24A 2QK7B 4P1YA 3O44A 1PVLA 4I0NA 5K59C 3LKFA
chains in the Genus database with same CATH topology
4TW1A 4U6VA 4P1XA 4YHDA 3M3RA 2LKFA 4P1YB 3M4DA 3B07A 3ANZA 7AHLA 1T5RA 4TW1B 4IYTA 4P1XB 5K59A 2YGTA 3ROHA 1LKFA 4IYCA 3M2LA 4H56A 4IDJA 4Q7GA 3B07B 4IYAA 2QK7A 3M4EA 4IZLA 4J0OA 4P24A 2QK7B 4P1YA 3O44A 1PVLA 4I0NA 5K59C 3LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TW1 A;  4U6V A;  4P1X A;  4YHD A;  3M3R A;  2LKF A;  4P1Y B;  3M4D A;  3B07 A;  3ANZ A;  7AHL A;  1T5R A;  4TW1 B;  4IYT A;  4P1X B;  5K59 A;  2YGT A;  3ROH A;  1LKF A;  4IYC A;  3M2L A;  4H56 A;  4IDJ A;  4Q7G A;  3B07 B;  4IYA A;  2QK7 A;  3M4E A;  4IZL A;  4J0O A;  4P24 A;  2QK7 B;  4P1Y A;  3O44 A;  1PVL A;  4I0N A;  5K59 C;  3LKF A; 
#chains in the Genus database with same CATH topology
 4TW1 A;  4U6V A;  4P1X A;  4YHD A;  3M3R A;  2LKF A;  4P1Y B;  3M4D A;  3B07 A;  3ANZ A;  7AHL A;  1T5R A;  4TW1 B;  4IYT A;  4P1X B;  5K59 A;  2YGT A;  3ROH A;  1LKF A;  4IYC A;  1XEZ A;  3M2L A;  4H56 A;  4IDJ A;  4Q7G A;  3B07 B;  4IYA A;  2QK7 A;  3M4E A;  4IZL A;  4J0O A;  4P24 A;  2QK7 B;  4P1Y A;  3O44 A;  1PVL A;  4I0N A;  5K59 C;  3LKF A; 
#chains in the Genus database with same CATH homology
 4TW1 A;  4U6V A;  4P1X A;  4YHD A;  3M3R A;  2LKF A;  4P1Y B;  3M4D A;  3B07 A;  3ANZ A;  7AHL A;  1T5R A;  4TW1 B;  4IYT A;  4P1X B;  5K59 A;  2YGT A;  3ROH A;  1LKF A;  4IYC A;  3M2L A;  4H56 A;  4IDJ A;  4Q7G A;  3B07 B;  4IYA A;  2QK7 A;  3M4E A;  4IZL A;  4J0O A;  4P24 A;  2QK7 B;  4P1Y A;  3O44 A;  1PVL A;  4I0N A;  5K59 C;  3LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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