4TW1B

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
289
structure length
282
Chain Sequence
TAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
source organism Staphylococcus aureus
publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
molecule keywords Possible leukocidin subunit
total genus 63
structure length 282
sequence length 289
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1B00
4U6VA 4IYTA 3M3RA 4TW1B 4YHDA 4TW1A 4IYCA 2LKFA 5K59C 5K59A 2YGTA 3M4DA 4P1XA 4P1YB 3ROHA 4IDJA 4P1YA 1T5RA 4P24A 4H56A 2QK7B 4Q7GA 3B07B 3LKFA 4IZLA 2QK7A 4J0OA 3B07A 4IYAA 4I0NA 1PVLA 3ANZA 3O44A 1LKFA 4P1XB 3M4EA 3M2LA 7AHLA
chains in the Genus database with same CATH superfamily
4U6VA 4IYTA 3M3RA 4TW1B 4YHDA 4TW1A 4IYCA 2LKFA 5K59C 5K59A 2YGTA 3M4DA 4P1XA 4P1YB 3ROHA 4IDJA 4P1YA 1T5RA 4P24A 4H56A 2QK7B 4Q7GA 3B07B 3LKFA 4IZLA 2QK7A 4J0OA 3B07A 4IYAA 4I0NA 1PVLA 3ANZA 1XEZA 3O44A 1LKFA 4P1XB 3M4EA 3M2LA 7AHLA
chains in the Genus database with same CATH topology
4U6VA 4IYTA 3M3RA 4TW1B 4YHDA 4TW1A 4IYCA 2LKFA 5K59C 5K59A 2YGTA 3M4DA 4P1XA 4P1YB 3ROHA 4IDJA 4P1YA 1T5RA 4P24A 4H56A 2QK7B 4Q7GA 3B07B 3LKFA 4IZLA 2QK7A 4J0OA 3B07A 4IYAA 4I0NA 1PVLA 3ANZA 3O44A 1LKFA 4P1XB 3M4EA 3M2LA 7AHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6V A;  4IYT A;  3M3R A;  4TW1 B;  4YHD A;  4TW1 A;  4IYC A;  2LKF A;  5K59 C;  5K59 A;  2YGT A;  3M4D A;  4P1X A;  4P1Y B;  3ROH A;  4IDJ A;  4P1Y A;  1T5R A;  4P24 A;  4H56 A;  2QK7 B;  4Q7G A;  3B07 B;  3LKF A;  4IZL A;  2QK7 A;  4J0O A;  3B07 A;  4IYA A;  4I0N A;  1PVL A;  3ANZ A;  3O44 A;  1LKF A;  4P1X B;  3M4E A;  3M2L A;  7AHL A; 
#chains in the Genus database with same CATH topology
 4U6V A;  4IYT A;  3M3R A;  4TW1 B;  4YHD A;  4TW1 A;  4IYC A;  2LKF A;  5K59 C;  5K59 A;  2YGT A;  3M4D A;  4P1X A;  4P1Y B;  3ROH A;  4IDJ A;  4P1Y A;  1T5R A;  4P24 A;  4H56 A;  2QK7 B;  4Q7G A;  3B07 B;  3LKF A;  4IZL A;  2QK7 A;  4J0O A;  3B07 A;  4IYA A;  4I0N A;  1PVL A;  3ANZ A;  1XEZ A;  3O44 A;  1LKF A;  4P1X B;  3M4E A;  3M2L A;  7AHL A; 
#chains in the Genus database with same CATH homology
 4U6V A;  4IYT A;  3M3R A;  4TW1 B;  4YHD A;  4TW1 A;  4IYC A;  2LKF A;  5K59 C;  5K59 A;  2YGT A;  3M4D A;  4P1X A;  4P1Y B;  3ROH A;  4IDJ A;  4P1Y A;  1T5R A;  4P24 A;  4H56 A;  2QK7 B;  4Q7G A;  3B07 B;  3LKF A;  4IZL A;  2QK7 A;  4J0O A;  3B07 A;  4IYA A;  4I0N A;  1PVL A;  3ANZ A;  3O44 A;  1LKF A;  4P1X B;  3M4E A;  3M2L A;  7AHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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