4TW1B

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 63
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
289
structure length
282
Chain Sequence
TAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus aureus
molecule keywords Possible leukocidin subunit
total genus 63
structure length 282
sequence length 289
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1B00
1T5RA 5K59C 3B07A 3M2LA 4IYAA 4P24A 2YGTA 4Q7GA 4P1XA 2LKFA 4P1YB 3O44A 4IZLA 3LKFA 4IDJA 4TW1B 4J0OA 3B07B 3ROHA 4IYTA 4I0NA 4YHDA 4P1XB 2QK7A 5K59A 4U6VA 1PVLA 3M4EA 1LKFA 3ANZA 3M3RA 4P1YA 4H56A 2QK7B 3M4DA 4IYCA 7AHLA 4TW1A
chains in the Genus database with same CATH superfamily
1T5RA 5K59C 3B07A 3M2LA 4IYAA 4P24A 2YGTA 4Q7GA 4P1XA 2LKFA 4P1YB 3O44A 4IZLA 3LKFA 4IDJA 4TW1B 4J0OA 3B07B 3ROHA 4IYTA 4I0NA 4YHDA 4P1XB 2QK7A 5K59A 1XEZA 4U6VA 1PVLA 3M4EA 1LKFA 3ANZA 3M3RA 4P1YA 4H56A 2QK7B 3M4DA 4IYCA 7AHLA 4TW1A
chains in the Genus database with same CATH topology
1T5RA 5K59C 3B07A 3M2LA 4IYAA 4P24A 2YGTA 4Q7GA 4P1XA 2LKFA 4P1YB 3O44A 4IZLA 3LKFA 4IDJA 4TW1B 4J0OA 3B07B 3ROHA 4IYTA 4I0NA 4YHDA 4P1XB 2QK7A 5K59A 4U6VA 1PVLA 3M4EA 1LKFA 3ANZA 3M3RA 4P1YA 4H56A 2QK7B 3M4DA 4IYCA 7AHLA 4TW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T5R A;  5K59 C;  3B07 A;  3M2L A;  4IYA A;  4P24 A;  2YGT A;  4Q7G A;  4P1X A;  2LKF A;  4P1Y B;  3O44 A;  4IZL A;  3LKF A;  4IDJ A;  4TW1 B;  4J0O A;  3B07 B;  3ROH A;  4IYT A;  4I0N A;  4YHD A;  4P1X B;  2QK7 A;  5K59 A;  4U6V A;  1PVL A;  3M4E A;  1LKF A;  3ANZ A;  3M3R A;  4P1Y A;  4H56 A;  2QK7 B;  3M4D A;  4IYC A;  7AHL A;  4TW1 A; 
#chains in the Genus database with same CATH topology
 1T5R A;  5K59 C;  3B07 A;  3M2L A;  4IYA A;  4P24 A;  2YGT A;  4Q7G A;  4P1X A;  2LKF A;  4P1Y B;  3O44 A;  4IZL A;  3LKF A;  4IDJ A;  4TW1 B;  4J0O A;  3B07 B;  3ROH A;  4IYT A;  4I0N A;  4YHD A;  4P1X B;  2QK7 A;  5K59 A;  1XEZ A;  4U6V A;  1PVL A;  3M4E A;  1LKF A;  3ANZ A;  3M3R A;  4P1Y A;  4H56 A;  2QK7 B;  3M4D A;  4IYC A;  7AHL A;  4TW1 A; 
#chains in the Genus database with same CATH homology
 1T5R A;  5K59 C;  3B07 A;  3M2L A;  4IYA A;  4P24 A;  2YGT A;  4Q7G A;  4P1X A;  2LKF A;  4P1Y B;  3O44 A;  4IZL A;  3LKF A;  4IDJ A;  4TW1 B;  4J0O A;  3B07 B;  3ROH A;  4IYT A;  4I0N A;  4YHD A;  4P1X B;  2QK7 A;  5K59 A;  4U6V A;  1PVL A;  3M4E A;  1LKF A;  3ANZ A;  3M3R A;  4P1Y A;  4H56 A;  2QK7 B;  3M4D A;  4IYC A;  7AHL A;  4TW1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...