4U6VA

Mechanisms of neutralization of a human anti-alpha toxin antibody
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
282
structure length
272
Chain Sequence
TDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Mechanisms of Neutralization of a Human Anti-alpha-toxin Antibody.
pubmed doi rcsb
molecule keywords Fab, antigen binding fragment, heavy chain
molecule tags Immune system
source organism Homo sapiens
total genus 68
structure length 272
sequence length 282
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4u6vA00
4YHDA 4IYAA 4IYTA 3LKFA 3M4EA 4TW1B 4Q7GA 3ROHA 4P1XB 1T5RA 3ANZA 4H56A 4IYCA 5K59C 2LKFA 4P24A 5K59A 7AHLA 3O44A 2QK7A 2YGTA 1PVLA 4P1YA 4IZLA 3M3RA 3B07A 4J0OA 4I0NA 3M2LA 4U6VA 2QK7B 3M4DA 4P1YB 4P1XA 4TW1A 4IDJA 3B07B 1LKFA
chains in the Genus database with same CATH superfamily
4YHDA 4IYAA 4IYTA 3LKFA 3M4EA 4TW1B 4Q7GA 3ROHA 4P1XB 1T5RA 3ANZA 4H56A 4IYCA 5K59C 2LKFA 4P24A 5K59A 7AHLA 3O44A 2QK7A 2YGTA 1PVLA 4P1YA 4IZLA 3M3RA 3B07A 4J0OA 4I0NA 3M2LA 4U6VA 2QK7B 1XEZA 3M4DA 4P1XA 4P1YB 4TW1A 4IDJA 3B07B 1LKFA
chains in the Genus database with same CATH topology
4YHDA 4IYAA 4IYTA 3LKFA 3M4EA 4TW1B 4Q7GA 3ROHA 4P1XB 1T5RA 3ANZA 4H56A 4IYCA 5K59C 2LKFA 4P24A 5K59A 7AHLA 3O44A 2QK7A 2YGTA 1PVLA 4P1YA 4IZLA 3M3RA 3B07A 4J0OA 4I0NA 3M2LA 4U6VA 2QK7B 3M4DA 4P1YB 4P1XA 4TW1A 4IDJA 3B07B 1LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YHD A;  4IYA A;  4IYT A;  3LKF A;  3M4E A;  4TW1 B;  4Q7G A;  3ROH A;  4P1X B;  1T5R A;  3ANZ A;  4H56 A;  4IYC A;  5K59 C;  2LKF A;  4P24 A;  5K59 A;  7AHL A;  3O44 A;  2QK7 A;  2YGT A;  1PVL A;  4P1Y A;  4IZL A;  3M3R A;  3B07 A;  4J0O A;  4I0N A;  3M2L A;  4U6V A;  2QK7 B;  3M4D A;  4P1Y B;  4P1X A;  4TW1 A;  4IDJ A;  3B07 B;  1LKF A; 
#chains in the Genus database with same CATH topology
 4YHD A;  4IYA A;  4IYT A;  3LKF A;  3M4E A;  4TW1 B;  4Q7G A;  3ROH A;  4P1X B;  1T5R A;  3ANZ A;  4H56 A;  4IYC A;  5K59 C;  2LKF A;  4P24 A;  5K59 A;  7AHL A;  3O44 A;  2QK7 A;  2YGT A;  1PVL A;  4P1Y A;  4IZL A;  3M3R A;  3B07 A;  4J0O A;  4I0N A;  3M2L A;  4U6V A;  2QK7 B;  1XEZ A;  3M4D A;  4P1X A;  4P1Y B;  4TW1 A;  4IDJ A;  3B07 B;  1LKF A; 
#chains in the Genus database with same CATH homology
 4YHD A;  4IYA A;  4IYT A;  3LKF A;  3M4E A;  4TW1 B;  4Q7G A;  3ROH A;  4P1X B;  1T5R A;  3ANZ A;  4H56 A;  4IYC A;  5K59 C;  2LKF A;  4P24 A;  5K59 A;  7AHL A;  3O44 A;  2QK7 A;  2YGT A;  1PVL A;  4P1Y A;  4IZL A;  3M3R A;  3B07 A;  4J0O A;  4I0N A;  3M2L A;  4U6V A;  2QK7 B;  3M4D A;  4P1Y B;  4P1X A;  4TW1 A;  4IDJ A;  3B07 B;  1LKF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...