4XQAA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0462
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
184
structure length
184
Chain Sequence
DTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber
total genus 44
structure length 184
sequence length 184
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2015-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4xqaA00
3O8EA 4XL8A 4XQAA 2J12A 4LIYA 4ZDGA 2J1KC 1H7ZA 1QIUA 1UXAA 3BQ4A 4WYJA 4K6UA 2QLKA 1UXBA 2WBWA 3N0IA 1NOBA 2BZVA 1P6AA 3QNDA 2WGTA 1KNBA 4K6TA 2WBVA 1P69A 4K6VA 2WGUA 2BZUA 3EXVA 3L89A 2J2JA 1QHVA 3CNCA 2W9LC 4ATZA 1UXEA 3EXWA 1KACA 3L88A 2O39A 3F0YA 2WSTA 4XQBA 4K6WA
chains in the Genus database with same CATH superfamily
3O8EA 4XL8A 4XQAA 2J12A 2JJLA 5MHSA 4LIYA 4ZDGA 2J1KC 4CW8A 1H7ZA 1QIUA 3S6XA 1UXAA 3BQ4A 4WYJA 4XC5A 4K6UA 2QLKA 1UXBA 2WBWA 3EOYA 3N0IA 4ODBA 3ZPEA 1NOBA 2BZVA 1P6AA 2OJ5A 3QNDA 2WGTA 1KNBA 2OJ6A 4K6TA 2WBVA 4GU3A 4D62A 1P69A 2VRSA 4K6VA 2WGUA 2BZUA 3EXVA 3ZPFA 1KKEA 3L89A 2J2JA 1QHVA 2IUNA 4K6WA 3CNCA 2W9LC 4ATZA 1UXEA 4GU4A 2IUMA 2BT8A 3EXWA 1KACA 2VTWA 3L88A 2O39A 3F0YA 4D63A 2BSFA 2WSTA 4XQBA 2BT7A
chains in the Genus database with same CATH topology
3O8EA 4XL8A 4XQAA 2J12A 4LIYA 4ZDGA 2J1KC 1H7ZA 1QIUA 1UXAA 3BQ4A 4WYJA 4K6UA 2QLKA 1UXBA 2WBWA 3N0IA 1NOBA 2BZVA 1P6AA 3QNDA 2WGTA 1KNBA 4K6TA 2WBVA 1P69A 4K6VA 2WGUA 2BZUA 3EXVA 3L89A 2J2JA 1QHVA 3CNCA 2W9LC 4ATZA 1UXEA 3EXWA 1KACA 3L88A 2O39A 3F0YA 2WSTA 4XQBA 4K6WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O8E A;  4XL8 A;  4XQA A;  2J12 A;  4LIY A;  4ZDG A;  2J1K C;  1H7Z A;  1QIU A;  1UXA A;  3BQ4 A;  4WYJ A;  4K6U A;  2QLK A;  1UXB A;  2WBW A;  3N0I A;  1NOB A;  2BZV A;  1P6A A;  3QND A;  2WGT A;  1KNB A;  4K6T A;  2WBV A;  1P69 A;  4K6V A;  2WGU A;  2BZU A;  3EXV A;  3L89 A;  2J2J A;  1QHV A;  3CNC A;  2W9L C;  4ATZ A;  1UXE A;  3EXW A;  1KAC A;  3L88 A;  2O39 A;  3F0Y A;  2WST A;  4XQB A;  4K6W A; 
#chains in the Genus database with same CATH topology
 3O8E A;  4XL8 A;  4XQA A;  2J12 A;  2JJL A;  5MHS A;  4LIY A;  4ZDG A;  2J1K C;  4CW8 A;  1H7Z A;  1QIU A;  3S6X A;  1UXA A;  3BQ4 A;  4WYJ A;  4XC5 A;  4K6U A;  2QLK A;  1UXB A;  2WBW A;  3EOY A;  3N0I A;  4ODB A;  3ZPE A;  1NOB A;  2BZV A;  1P6A A;  2OJ5 A;  3QND A;  2WGT A;  1KNB A;  2OJ6 A;  4K6T A;  2WBV A;  4GU3 A;  4D62 A;  1P69 A;  2VRS A;  4K6V A;  2WGU A;  2BZU A;  3EXV A;  3ZPF A;  1KKE A;  3L89 A;  2J2J A;  1QHV A;  2IUN A;  4K6W A;  3CNC A;  2W9L C;  4ATZ A;  1UXE A;  4GU4 A;  2IUM A;  2BT8 A;  3EXW A;  1KAC A;  2VTW A;  3L88 A;  2O39 A;  3F0Y A;  4D63 A;  2BSF A;  2WST A;  4XQB A;  2BT7 A; 
#chains in the Genus database with same CATH homology
 3O8E A;  4XL8 A;  4XQA A;  2J12 A;  4LIY A;  4ZDG A;  2J1K C;  1H7Z A;  1QIU A;  1UXA A;  3BQ4 A;  4WYJ A;  4K6U A;  2QLK A;  1UXB A;  2WBW A;  3N0I A;  1NOB A;  2BZV A;  1P6A A;  3QND A;  2WGT A;  1KNB A;  4K6T A;  2WBV A;  1P69 A;  4K6V A;  2WGU A;  2BZU A;  3EXV A;  3L89 A;  2J2J A;  1QHV A;  3CNC A;  2W9L C;  4ATZ A;  1UXE A;  3EXW A;  1KAC A;  3L88 A;  2O39 A;  3F0Y A;  2WST A;  4XQB A;  4K6W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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