5K59A

Crystal structure of lukgh from staphylococcus aureus in complex with a neutralising antibody
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
295
structure length
292
Chain Sequence
EKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLND
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
pubmed doi rcsb
molecule tags Immune system
source organism Staphylococcus aureus (strain usa300)
molecule keywords Uncharacterized leukocidin-like protein 2
total genus 75
structure length 292
sequence length 295
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 5k59A00
3M2LA 2YGTA 4H56A 4TW1A 4U6VA 4IYAA 4P24A 4IZLA 3ROHA 3O44A 3M3RA 4TW1B 1T5RA 4IYTA 4P1YA 1LKFA 5K59C 3M4DA 4P1XA 4IYCA 3LKFA 3B07A 4P1YB 3ANZA 4P1XB 2QK7A 3B07B 4J0OA 4I0NA 5K59A 1PVLA 2LKFA 4YHDA 4Q7GA 7AHLA 2QK7B 3M4EA 4IDJA
chains in the Genus database with same CATH superfamily
3M2LA 1XEZA 2YGTA 4H56A 4TW1A 4U6VA 4IYAA 4P24A 4IZLA 3ROHA 3O44A 3M3RA 4TW1B 1T5RA 4IYTA 4P1YA 1LKFA 5K59C 3M4DA 4P1XA 4IYCA 3LKFA 3B07A 4P1YB 3ANZA 4P1XB 2QK7A 4IDJA 3B07B 4J0OA 4I0NA 5K59A 1PVLA 2LKFA 4YHDA 4Q7GA 7AHLA 2QK7B 3M4EA
chains in the Genus database with same CATH topology
3M2LA 2YGTA 4H56A 4TW1A 4U6VA 4IYAA 4P24A 4IZLA 3ROHA 3O44A 3M3RA 4TW1B 1T5RA 4IYTA 4P1YA 1LKFA 5K59C 3M4DA 4P1XA 4IYCA 3LKFA 3B07A 4P1YB 3ANZA 4P1XB 2QK7A 3B07B 4J0OA 4I0NA 5K59A 1PVLA 2LKFA 4YHDA 4Q7GA 7AHLA 2QK7B 3M4EA 4IDJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M2L A;  2YGT A;  4H56 A;  4TW1 A;  4U6V A;  4IYA A;  4P24 A;  4IZL A;  3ROH A;  3O44 A;  3M3R A;  4TW1 B;  1T5R A;  4IYT A;  4P1Y A;  1LKF A;  5K59 C;  3M4D A;  4P1X A;  4IYC A;  3LKF A;  3B07 A;  4P1Y B;  3ANZ A;  4P1X B;  2QK7 A;  3B07 B;  4J0O A;  4I0N A;  5K59 A;  1PVL A;  2LKF A;  4YHD A;  4Q7G A;  7AHL A;  2QK7 B;  3M4E A;  4IDJ A; 
#chains in the Genus database with same CATH topology
 3M2L A;  1XEZ A;  2YGT A;  4H56 A;  4TW1 A;  4U6V A;  4IYA A;  4P24 A;  4IZL A;  3ROH A;  3O44 A;  3M3R A;  4TW1 B;  1T5R A;  4IYT A;  4P1Y A;  1LKF A;  5K59 C;  3M4D A;  4P1X A;  4IYC A;  3LKF A;  3B07 A;  4P1Y B;  3ANZ A;  4P1X B;  2QK7 A;  4IDJ A;  3B07 B;  4J0O A;  4I0N A;  5K59 A;  1PVL A;  2LKF A;  4YHD A;  4Q7G A;  7AHL A;  2QK7 B;  3M4E A; 
#chains in the Genus database with same CATH homology
 3M2L A;  2YGT A;  4H56 A;  4TW1 A;  4U6V A;  4IYA A;  4P24 A;  4IZL A;  3ROH A;  3O44 A;  3M3R A;  4TW1 B;  1T5R A;  4IYT A;  4P1Y A;  1LKF A;  5K59 C;  3M4D A;  4P1X A;  4IYC A;  3LKF A;  3B07 A;  4P1Y B;  3ANZ A;  4P1X B;  2QK7 A;  3B07 B;  4J0O A;  4I0N A;  5K59 A;  1PVL A;  2LKF A;  4YHD A;  4Q7G A;  7AHL A;  2QK7 B;  3M4E A;  4IDJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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