5K59C

Crystal structure of lukgh from staphylococcus aureus in complex with a neutralising antibody
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
282
structure length
276
Chain Sequence
KNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
pubmed doi rcsb
molecule keywords Uncharacterized leukocidin-like protein 2
molecule tags Immune system
source organism Staphylococcus aureus (strain usa300)
total genus 79
structure length 276
sequence length 282
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 5k59C00
4P24A 3M3RA 2QK7B 4IYCA 4IYTA 4I0NA 4IYAA 3B07A 3B07B 4YHDA 1T5RA 4J0OA 3M4EA 5K59C 7AHLA 4H56A 1PVLA 4Q7GA 4P1XA 3ANZA 4P1XB 3O44A 3ROHA 2LKFA 4U6VA 3M2LA 4IZLA 3M4DA 3LKFA 4IDJA 4P1YA 4P1YB 4TW1A 4TW1B 2YGTA 5K59A 1LKFA 2QK7A
chains in the Genus database with same CATH superfamily
4P24A 3M3RA 2QK7B 4IYCA 1XEZA 4IYTA 4I0NA 4IYAA 3B07A 3B07B 4YHDA 1T5RA 4J0OA 3M4EA 5K59C 7AHLA 4H56A 1PVLA 4Q7GA 4P1XA 3ANZA 4P1XB 3O44A 3ROHA 2LKFA 4U6VA 3M2LA 4IZLA 3M4DA 3LKFA 4IDJA 4P1YA 4P1YB 4TW1A 4TW1B 2YGTA 5K59A 1LKFA 2QK7A
chains in the Genus database with same CATH topology
4P24A 3M3RA 2QK7B 4IYCA 4IYTA 4I0NA 4IYAA 3B07A 3B07B 4YHDA 1T5RA 4J0OA 3M4EA 5K59C 7AHLA 4H56A 1PVLA 4Q7GA 4P1XA 3ANZA 4P1XB 3O44A 3ROHA 2LKFA 4U6VA 3M2LA 4IZLA 3M4DA 3LKFA 4IDJA 4P1YA 4P1YB 4TW1A 4TW1B 2YGTA 5K59A 1LKFA 2QK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P24 A;  3M3R A;  2QK7 B;  4IYC A;  4IYT A;  4I0N A;  4IYA A;  3B07 A;  3B07 B;  4YHD A;  1T5R A;  4J0O A;  3M4E A;  5K59 C;  7AHL A;  4H56 A;  1PVL A;  4Q7G A;  4P1X A;  3ANZ A;  4P1X B;  3O44 A;  3ROH A;  2LKF A;  4U6V A;  3M2L A;  4IZL A;  3M4D A;  3LKF A;  4IDJ A;  4P1Y A;  4P1Y B;  4TW1 A;  4TW1 B;  2YGT A;  5K59 A;  1LKF A;  2QK7 A; 
#chains in the Genus database with same CATH topology
 4P24 A;  3M3R A;  2QK7 B;  4IYC A;  1XEZ A;  4IYT A;  4I0N A;  4IYA A;  3B07 A;  3B07 B;  4YHD A;  1T5R A;  4J0O A;  3M4E A;  5K59 C;  7AHL A;  4H56 A;  1PVL A;  4Q7G A;  4P1X A;  3ANZ A;  4P1X B;  3O44 A;  3ROH A;  2LKF A;  4U6V A;  3M2L A;  4IZL A;  3M4D A;  3LKF A;  4IDJ A;  4P1Y A;  4P1Y B;  4TW1 A;  4TW1 B;  2YGT A;  5K59 A;  1LKF A;  2QK7 A; 
#chains in the Genus database with same CATH homology
 4P24 A;  3M3R A;  2QK7 B;  4IYC A;  4IYT A;  4I0N A;  4IYA A;  3B07 A;  3B07 B;  4YHD A;  1T5R A;  4J0O A;  3M4E A;  5K59 C;  7AHL A;  4H56 A;  1PVL A;  4Q7G A;  4P1X A;  3ANZ A;  4P1X B;  3O44 A;  3ROH A;  2LKF A;  4U6V A;  3M2L A;  4IZL A;  3M4D A;  3LKF A;  4IDJ A;  4P1Y A;  4P1Y B;  4TW1 A;  4TW1 B;  2YGT A;  5K59 A;  1LKF A;  2QK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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