7AHLA

Alpha-hemolysin from staphylococcus aureus
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
pubmed doi rcsb
molecule tags Cytolytic protein
molecule keywords ALPHA-HEMOLYSIN
total genus 54
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 1996-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 7ahlA00
2QK7B 2QK7A 4P1YA 3ANZA 1LKFA 4P1XB 3ROHA 4U6VA 4P1XA 2YGTA 4IZLA 1PVLA 2LKFA 3LKFA 4Q7GA 4H56A 4IDJA 1T5RA 7AHLA 3M4DA 3B07B 4TW1B 4P24A 4J0OA 4TW1A 3B07A 3O44A 4YHDA 4I0NA 4IYCA 5K59C 3M2LA 3M4EA 4IYTA 3M3RA 4P1YB 5K59A 4IYAA
chains in the Genus database with same CATH superfamily
2QK7B 2QK7A 4P1YA 3ANZA 1LKFA 4P1XB 3ROHA 4U6VA 4P1XA 1XEZA 2YGTA 4IZLA 1PVLA 2LKFA 3LKFA 4Q7GA 4H56A 4IDJA 1T5RA 7AHLA 3M4DA 3B07B 4TW1B 4P24A 4J0OA 4TW1A 3B07A 3O44A 4YHDA 4I0NA 4IYCA 5K59C 3M2LA 3M4EA 4IYTA 3M3RA 4P1YB 5K59A 4IYAA
chains in the Genus database with same CATH topology
2QK7B 2QK7A 4P1YA 3ANZA 1LKFA 4P1XB 3ROHA 4U6VA 4P1XA 2YGTA 4IZLA 1PVLA 2LKFA 3LKFA 4Q7GA 4H56A 4IDJA 1T5RA 7AHLA 3M4DA 3B07B 4TW1B 4P24A 4J0OA 4TW1A 3B07A 3O44A 4YHDA 4I0NA 4IYCA 5K59C 3M2LA 3M4EA 4IYTA 3M3RA 4P1YB 5K59A 4IYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QK7 B;  2QK7 A;  4P1Y A;  3ANZ A;  1LKF A;  4P1X B;  3ROH A;  4U6V A;  4P1X A;  2YGT A;  4IZL A;  1PVL A;  2LKF A;  3LKF A;  4Q7G A;  4H56 A;  4IDJ A;  1T5R A;  7AHL A;  3M4D A;  3B07 B;  4TW1 B;  4P24 A;  4J0O A;  4TW1 A;  3B07 A;  3O44 A;  4YHD A;  4I0N A;  4IYC A;  5K59 C;  3M2L A;  3M4E A;  4IYT A;  3M3R A;  4P1Y B;  5K59 A;  4IYA A; 
#chains in the Genus database with same CATH topology
 2QK7 B;  2QK7 A;  4P1Y A;  3ANZ A;  1LKF A;  4P1X B;  3ROH A;  4U6V A;  4P1X A;  1XEZ A;  2YGT A;  4IZL A;  1PVL A;  2LKF A;  3LKF A;  4Q7G A;  4H56 A;  4IDJ A;  1T5R A;  7AHL A;  3M4D A;  3B07 B;  4TW1 B;  4P24 A;  4J0O A;  4TW1 A;  3B07 A;  3O44 A;  4YHD A;  4I0N A;  4IYC A;  5K59 C;  3M2L A;  3M4E A;  4IYT A;  3M3R A;  4P1Y B;  5K59 A;  4IYA A; 
#chains in the Genus database with same CATH homology
 2QK7 B;  2QK7 A;  4P1Y A;  3ANZ A;  1LKF A;  4P1X B;  3ROH A;  4U6V A;  4P1X A;  2YGT A;  4IZL A;  1PVL A;  2LKF A;  3LKF A;  4Q7G A;  4H56 A;  4IDJ A;  1T5R A;  7AHL A;  3M4D A;  3B07 B;  4TW1 B;  4P24 A;  4J0O A;  4TW1 A;  3B07 A;  3O44 A;  4YHD A;  4I0N A;  4IYC A;  5K59 C;  3M2L A;  3M4E A;  4IYT A;  3M3R A;  4P1Y B;  5K59 A;  4IYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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