7AHLA

Alpha-hemolysin from staphylococcus aureus
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cytolytic protein
publication title Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
pubmed doi rcsb
molecule keywords ALPHA-HEMOLYSIN
total genus 54
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 1996-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 7ahlA00
1LKFA 4IYAA 4IDJA 2QK7A 7AHLA 5K59A 2QK7B 3M2LA 4TW1A 4U6VA 3B07A 3O44A 3ROHA 4P1YA 1PVLA 1T5RA 4IYCA 4H56A 4J0OA 2YGTA 4TW1B 3M4DA 5K59C 2LKFA 3B07B 4P1YB 3M3RA 4P1XA 3ANZA 4P24A 4IZLA 4YHDA 3LKFA 4IYTA 4P1XB 3M4EA 4Q7GA 4I0NA
chains in the Genus database with same CATH superfamily
1LKFA 4IYAA 4IDJA 2QK7A 7AHLA 5K59A 2QK7B 3M2LA 4TW1A 4U6VA 3B07A 3O44A 3ROHA 4P1YA 1PVLA 1T5RA 4IYCA 4H56A 4J0OA 2YGTA 4TW1B 3M4DA 5K59C 2LKFA 3B07B 4P1YB 3M3RA 4P1XA 3ANZA 4P24A 4IZLA 4YHDA 3LKFA 4IYTA 4P1XB 3M4EA 4Q7GA 1XEZA 4I0NA
chains in the Genus database with same CATH topology
1LKFA 4IYAA 4IDJA 2QK7A 7AHLA 5K59A 2QK7B 3M2LA 4TW1A 4U6VA 3B07A 3O44A 3ROHA 4P1YA 1PVLA 1T5RA 4IYCA 4H56A 4J0OA 2YGTA 4TW1B 3M4DA 5K59C 2LKFA 3B07B 4P1YB 3M3RA 4P1XA 3ANZA 4P24A 4IZLA 4YHDA 3LKFA 4IYTA 4P1XB 3M4EA 4Q7GA 4I0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LKF A;  4IYA A;  4IDJ A;  2QK7 A;  7AHL A;  5K59 A;  2QK7 B;  3M2L A;  4TW1 A;  4U6V A;  3B07 A;  3O44 A;  3ROH A;  4P1Y A;  1PVL A;  1T5R A;  4IYC A;  4H56 A;  4J0O A;  2YGT A;  4TW1 B;  3M4D A;  5K59 C;  2LKF A;  3B07 B;  4P1Y B;  3M3R A;  4P1X A;  3ANZ A;  4P24 A;  4IZL A;  4YHD A;  3LKF A;  4IYT A;  4P1X B;  3M4E A;  4Q7G A;  4I0N A; 
#chains in the Genus database with same CATH topology
 1LKF A;  4IYA A;  4IDJ A;  2QK7 A;  7AHL A;  5K59 A;  2QK7 B;  3M2L A;  4TW1 A;  4U6V A;  3B07 A;  3O44 A;  3ROH A;  4P1Y A;  1PVL A;  1T5R A;  4IYC A;  4H56 A;  4J0O A;  2YGT A;  4TW1 B;  3M4D A;  5K59 C;  2LKF A;  3B07 B;  4P1Y B;  3M3R A;  4P1X A;  3ANZ A;  4P24 A;  4IZL A;  4YHD A;  3LKF A;  4IYT A;  4P1X B;  3M4E A;  4Q7G A;  1XEZ A;  4I0N A; 
#chains in the Genus database with same CATH homology
 1LKF A;  4IYA A;  4IDJ A;  2QK7 A;  7AHL A;  5K59 A;  2QK7 B;  3M2L A;  4TW1 A;  4U6V A;  3B07 A;  3O44 A;  3ROH A;  4P1Y A;  1PVL A;  1T5R A;  4IYC A;  4H56 A;  4J0O A;  2YGT A;  4TW1 B;  3M4D A;  5K59 C;  2LKF A;  3B07 B;  4P1Y B;  3M3R A;  4P1X A;  3ANZ A;  4P24 A;  4IZL A;  4YHD A;  3LKF A;  4IYT A;  4P1X B;  3M4E A;  4Q7G A;  4I0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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