7AHLA

Alpha-hemolysin from staphylococcus aureus
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
pubmed doi rcsb
molecule tags Cytolytic protein
molecule keywords ALPHA-HEMOLYSIN
total genus 54
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 1996-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 7ahlA00
4P1YA 3ROHA 2LKFA 4IZLA 1PVLA 3M4DA 4TW1A 3O44A 1LKFA 5K59C 4H56A 3M3RA 4P1XB 4IYTA 3ANZA 4Q7GA 3B07B 4P24A 4P1XA 1T5RA 7AHLA 4U6VA 3M2LA 3B07A 3M4EA 4YHDA 2QK7B 4IDJA 4IYCA 2QK7A 4P1YB 5K59A 4IYAA 3LKFA 4TW1B 4I0NA 4J0OA 2YGTA
chains in the Genus database with same CATH superfamily
4P1YA 3ROHA 2LKFA 4IZLA 1PVLA 3M4DA 4TW1A 3O44A 1LKFA 5K59C 4H56A 3M3RA 1XEZA 4P1XB 4IYTA 3ANZA 4Q7GA 3B07B 4P24A 4P1XA 1T5RA 7AHLA 4U6VA 3M2LA 3B07A 3M4EA 4YHDA 2QK7B 4IDJA 4IYCA 2QK7A 4P1YB 5K59A 4IYAA 3LKFA 4TW1B 4I0NA 4J0OA 2YGTA
chains in the Genus database with same CATH topology
4P1YA 3ROHA 2LKFA 4IZLA 1PVLA 3M4DA 4TW1A 3O44A 1LKFA 5K59C 4H56A 3M3RA 4P1XB 4IYTA 3ANZA 4Q7GA 3B07B 4P24A 4P1XA 1T5RA 7AHLA 4U6VA 3M2LA 3B07A 3M4EA 4YHDA 2QK7B 4IDJA 4IYCA 2QK7A 4P1YB 5K59A 4IYAA 3LKFA 4TW1B 4I0NA 4J0OA 2YGTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1Y A;  3ROH A;  2LKF A;  4IZL A;  1PVL A;  3M4D A;  4TW1 A;  3O44 A;  1LKF A;  5K59 C;  4H56 A;  3M3R A;  4P1X B;  4IYT A;  3ANZ A;  4Q7G A;  3B07 B;  4P24 A;  4P1X A;  1T5R A;  7AHL A;  4U6V A;  3M2L A;  3B07 A;  3M4E A;  4YHD A;  2QK7 B;  4IDJ A;  4IYC A;  2QK7 A;  4P1Y B;  5K59 A;  4IYA A;  3LKF A;  4TW1 B;  4I0N A;  4J0O A;  2YGT A; 
#chains in the Genus database with same CATH topology
 4P1Y A;  3ROH A;  2LKF A;  4IZL A;  1PVL A;  3M4D A;  4TW1 A;  3O44 A;  1LKF A;  5K59 C;  4H56 A;  3M3R A;  1XEZ A;  4P1X B;  4IYT A;  3ANZ A;  4Q7G A;  3B07 B;  4P24 A;  4P1X A;  1T5R A;  7AHL A;  4U6V A;  3M2L A;  3B07 A;  3M4E A;  4YHD A;  2QK7 B;  4IDJ A;  4IYC A;  2QK7 A;  4P1Y B;  5K59 A;  4IYA A;  3LKF A;  4TW1 B;  4I0N A;  4J0O A;  2YGT A; 
#chains in the Genus database with same CATH homology
 4P1Y A;  3ROH A;  2LKF A;  4IZL A;  1PVL A;  3M4D A;  4TW1 A;  3O44 A;  1LKF A;  5K59 C;  4H56 A;  3M3R A;  4P1X B;  4IYT A;  3ANZ A;  4Q7G A;  3B07 B;  4P24 A;  4P1X A;  1T5R A;  7AHL A;  4U6V A;  3M2L A;  3B07 A;  3M4E A;  4YHD A;  2QK7 B;  4IDJ A;  4IYC A;  2QK7 A;  4P1Y B;  5K59 A;  4IYA A;  3LKF A;  4TW1 B;  4I0N A;  4J0O A;  2YGT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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