3ANZA

Crystal structure of alpha-hemolysin
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
295
structure length
295
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTNLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
source organism Staphylococcus aureus
publication title 2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal alpha-hemolysin into heptameric pore structure
pubmed doi rcsb
molecule keywords Alpha-hemolysin
total genus 63
structure length 295
sequence length 295
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b
ec nomenclature
pdb deposition date 2010-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3anzA00
3ANZA 4TW1A 4P1XA 4P24A 2QK7B 2LKFA 3ROHA 4P1XB 3O44A 4TW1B 4YHDA 4P1YA 4Q7GA 4U6VA 7AHLA 3M2LA 2YGTA 3LKFA 4P1YB 5K59C 3M3RA 3B07A 1T5RA 4IZLA 3M4EA 4IDJA 1LKFA 4IYTA 2QK7A 4H56A 3B07B 4I0NA 4J0OA 5K59A 1PVLA 4IYAA 3M4DA 4IYCA
chains in the Genus database with same CATH superfamily
3ANZA 4TW1A 4P1XA 4P24A 2QK7B 2LKFA 3ROHA 4P1XB 3O44A 4TW1B 4YHDA 4P1YA 4Q7GA 4U6VA 1XEZA 7AHLA 3M2LA 2YGTA 3LKFA 4P1YB 5K59C 3M3RA 3B07A 1T5RA 4IZLA 3M4EA 4IDJA 1LKFA 4IYTA 2QK7A 4H56A 3B07B 4I0NA 4J0OA 5K59A 1PVLA 4IYAA 3M4DA 4IYCA
chains in the Genus database with same CATH topology
3ANZA 4TW1A 4P1XA 4P24A 2QK7B 2LKFA 3ROHA 4P1XB 3O44A 4TW1B 4YHDA 4P1YA 4Q7GA 4U6VA 7AHLA 3M2LA 2YGTA 3LKFA 4P1YB 5K59C 3M3RA 3B07A 1T5RA 4IZLA 3M4EA 4IDJA 1LKFA 4IYTA 2QK7A 4H56A 3B07B 4I0NA 4J0OA 5K59A 1PVLA 4IYAA 3M4DA 4IYCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ANZ A;  4TW1 A;  4P1X A;  4P24 A;  2QK7 B;  2LKF A;  3ROH A;  4P1X B;  3O44 A;  4TW1 B;  4YHD A;  4P1Y A;  4Q7G A;  4U6V A;  7AHL A;  3M2L A;  2YGT A;  3LKF A;  4P1Y B;  5K59 C;  3M3R A;  3B07 A;  1T5R A;  4IZL A;  3M4E A;  4IDJ A;  1LKF A;  4IYT A;  2QK7 A;  4H56 A;  3B07 B;  4I0N A;  4J0O A;  5K59 A;  1PVL A;  4IYA A;  3M4D A;  4IYC A; 
#chains in the Genus database with same CATH topology
 3ANZ A;  4TW1 A;  4P1X A;  4P24 A;  2QK7 B;  2LKF A;  3ROH A;  4P1X B;  3O44 A;  4TW1 B;  4YHD A;  4P1Y A;  4Q7G A;  4U6V A;  1XEZ A;  7AHL A;  3M2L A;  2YGT A;  3LKF A;  4P1Y B;  5K59 C;  3M3R A;  3B07 A;  1T5R A;  4IZL A;  3M4E A;  4IDJ A;  1LKF A;  4IYT A;  2QK7 A;  4H56 A;  3B07 B;  4I0N A;  4J0O A;  5K59 A;  1PVL A;  4IYA A;  3M4D A;  4IYC A; 
#chains in the Genus database with same CATH homology
 3ANZ A;  4TW1 A;  4P1X A;  4P24 A;  2QK7 B;  2LKF A;  3ROH A;  4P1X B;  3O44 A;  4TW1 B;  4YHD A;  4P1Y A;  4Q7G A;  4U6V A;  7AHL A;  3M2L A;  2YGT A;  3LKF A;  4P1Y B;  5K59 C;  3M3R A;  3B07 A;  1T5R A;  4IZL A;  3M4E A;  4IDJ A;  1LKF A;  4IYT A;  2QK7 A;  4H56 A;  3B07 B;  4I0N A;  4J0O A;  5K59 A;  1PVL A;  4IYA A;  3M4D A;  4IYC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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