3ANZA

Crystal structure of alpha-hemolysin
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
295
structure length
295
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTNLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal alpha-hemolysin into heptameric pore structure
pubmed doi rcsb
molecule tags Toxin
source organism Staphylococcus aureus
molecule keywords Alpha-hemolysin
total genus 63
structure length 295
sequence length 295
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b
ec nomenclature
pdb deposition date 2010-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3anzA00
2YGTA 4J0OA 1LKFA 3M4DA 4P1YB 7AHLA 4IDJA 4P1YA 3B07B 4P24A 4IYCA 3M2LA 3B07A 4YHDA 2QK7B 3M3RA 1T5RA 4IYTA 5K59C 3ANZA 2QK7A 4H56A 4Q7GA 4IYAA 4P1XB 3M4EA 5K59A 2LKFA 4I0NA 1PVLA 3O44A 4P1XA 4TW1B 4U6VA 4IZLA 3LKFA 3ROHA 4TW1A
chains in the Genus database with same CATH superfamily
2YGTA 4J0OA 1LKFA 3M4DA 4P1YB 7AHLA 4IDJA 4P1YA 3B07B 4P24A 4IYCA 3M2LA 1XEZA 3B07A 4YHDA 2QK7B 3M3RA 1T5RA 4IYTA 5K59C 3ANZA 2QK7A 4H56A 4Q7GA 4IYAA 4P1XB 3M4EA 5K59A 2LKFA 4I0NA 1PVLA 3O44A 4P1XA 4TW1B 4U6VA 4IZLA 3LKFA 3ROHA 4TW1A
chains in the Genus database with same CATH topology
2YGTA 4J0OA 1LKFA 3M4DA 4P1YB 7AHLA 4IDJA 4P1YA 3B07B 4P24A 4IYCA 3M2LA 3B07A 4YHDA 2QK7B 3M3RA 1T5RA 4IYTA 5K59C 3ANZA 2QK7A 4H56A 4Q7GA 4IYAA 4P1XB 3M4EA 5K59A 2LKFA 4I0NA 1PVLA 3O44A 4P1XA 4TW1B 4U6VA 4IZLA 3LKFA 3ROHA 4TW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YGT A;  4J0O A;  1LKF A;  3M4D A;  4P1Y B;  7AHL A;  4IDJ A;  4P1Y A;  3B07 B;  4P24 A;  4IYC A;  3M2L A;  3B07 A;  4YHD A;  2QK7 B;  3M3R A;  1T5R A;  4IYT A;  5K59 C;  3ANZ A;  2QK7 A;  4H56 A;  4Q7G A;  4IYA A;  4P1X B;  3M4E A;  5K59 A;  2LKF A;  4I0N A;  1PVL A;  3O44 A;  4P1X A;  4TW1 B;  4U6V A;  4IZL A;  3LKF A;  3ROH A;  4TW1 A; 
#chains in the Genus database with same CATH topology
 2YGT A;  4J0O A;  1LKF A;  3M4D A;  4P1Y B;  7AHL A;  4IDJ A;  4P1Y A;  3B07 B;  4P24 A;  4IYC A;  3M2L A;  1XEZ A;  3B07 A;  4YHD A;  2QK7 B;  3M3R A;  1T5R A;  4IYT A;  5K59 C;  3ANZ A;  2QK7 A;  4H56 A;  4Q7G A;  4IYA A;  4P1X B;  3M4E A;  5K59 A;  2LKF A;  4I0N A;  1PVL A;  3O44 A;  4P1X A;  4TW1 B;  4U6V A;  4IZL A;  3LKF A;  3ROH A;  4TW1 A; 
#chains in the Genus database with same CATH homology
 2YGT A;  4J0O A;  1LKF A;  3M4D A;  4P1Y B;  7AHL A;  4IDJ A;  4P1Y A;  3B07 B;  4P24 A;  4IYC A;  3M2L A;  3B07 A;  4YHD A;  2QK7 B;  3M3R A;  1T5R A;  4IYT A;  5K59 C;  3ANZ A;  2QK7 A;  4H56 A;  4Q7G A;  4IYA A;  4P1X B;  3M4E A;  5K59 A;  2LKF A;  4I0N A;  1PVL A;  3O44 A;  4P1X A;  4TW1 B;  4U6V A;  4IZL A;  3LKF A;  3ROH A;  4TW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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