The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
52
|
sequence length |
208
|
structure length |
208
|
Chain Sequence |
MKGDEIYEDLMRLESVPTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation.
pubmed doi rcsb |
| molecule tags |
Signaling protein
|
| source organism |
Mus musculus
|
| molecule keywords |
RHO-GEF VAV
|
| total genus |
52
|
| structure length |
208
|
| sequence length |
208
|
| ec nomenclature | |
| pdb deposition date | 2000-06-18 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00621 | RhoGEF | RhoGEF domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Dbl Homology Domain; Chain A | Dbl homology (DH) domain |
#chains in the Genus database with same CATH superfamily 1KI1 B; 4GYV A; 4MT7 A; 3ODW A; 3MPX A; 2Z0Q A; 2RGN B; 1TXD A; 1NTY A; 3KZ1 A; 3EO2 A; 2PZ1 A; 1FOE A; 1BY1 A; 2DX1 A; 4GOU A; 1KZG A; 1KZ7 A; 5JHG A; 1RJ2 A; 1LB1 A; 3JV3 A; 2VRW B; 5JHH A; 1XD4 A; 4GZU A; 3KSY A; 4D0O A; 5FI1 A; 3BJI A; 3QBV B; 2KR9 A; 1F5X A; 3P6A A; 2DFK A; 1DBH A; 4YON A; 4D0N B; 1XCG A; 3ODO A; 3T06 A; 3ODX A; 1X86 A; 3GF9 A; 2NZ8 B; 3KY9 A; 5FI0 A; #chains in the Genus database with same CATH topology 1KI1 B; 4GYV A; 4MT7 A; 3ODW A; 3MPX A; 2Z0Q A; 2RGN B; 1TXD A; 1NTY A; 3KZ1 A; 3EO2 A; 2PZ1 A; 1FOE A; 1BY1 A; 2DX1 A; 4GOU A; 1KZG A; 1KZ7 A; 5JHG A; 1RJ2 A; 1LB1 A; 3JV3 A; 2VRW B; 5JHH A; 1XD4 A; 4GZU A; 3KSY A; 4D0O A; 5FI1 A; 3BJI A; 3QBV B; 2KR9 A; 1F5X A; 3P6A A; 2DFK A; 1DBH A; 4YON A; 4D0N B; 1XCG A; 3ODO A; 3T06 A; 3ODX A; 1X86 A; 3GF9 A; 2NZ8 B; 3KY9 A; 5FI0 A; #chains in the Genus database with same CATH homology 1KI1 B; 4GYV A; 4MT7 A; 3ODW A; 3MPX A; 2Z0Q A; 2RGN B; 1TXD A; 1NTY A; 3KZ1 A; 3EO2 A; 2PZ1 A; 1FOE A; 1BY1 A; 2DX1 A; 4GOU A; 1KZG A; 1KZ7 A; 5JHG A; 1RJ2 A; 1LB1 A; 3JV3 A; 2VRW B; 5JHH A; 1XD4 A; 4GZU A; 3KSY A; 4D0O A; 5FI1 A; 3BJI A; 3QBV B; 2KR9 A; 1F5X A; 3P6A A; 2DFK A; 1DBH A; 4YON A; 4D0N B; 1XCG A; 3ODO A; 3T06 A; 3ODX A; 1X86 A; 3GF9 A; 2NZ8 B; 3KY9 A; 5FI0 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
