2KR9 | Genus

Total Genus 58

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	58
sequence length	190
structure length	190
Chain Sequence	GPLGSPEFPGRKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRVTKYQLLLKELLTCCEEGKGELKDGLEVMLSVPKKANDAMHV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 190 atoms

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190 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Rattus norvegicus
publication title	The solution NMR structure of the first Dbl domain of RhoGEF Kalirin. rcsb
molecule keywords	Kalirin
total genus	58
structure length	190
sequence length	190
ec nomenclature	ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date	2009-12-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	2kr9A00

1X86A 4MT7A 1XCGA 3KZ1A 3ODXA 5FI0A 3EO2A 1KI1B 1RJ2A 2NZ8B 2Z0QA 1BY1A 4YONA 3ODOA 4GZUA 3QBVB 2DFKA 2VRWB 3JV3A 1TXDA 5JHGA 5FI1A 1KZ7A 3GF9A 1NTYA 1LB1A 4GOUA 2PZ1A 3BJIA 2DX1A 3T06A 1KZGA 4D0OA 4D0NB 3KY9A 2KR9A 3KSYA 2RGNB 3P6AA 5JHHA 3MPXA 1FOEA 4GYVA 1DBHA 1XD4A 3ODWA 1F5XA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1X86 A;  4MT7 A;  1XCG A;  3KZ1 A;  3ODX A;  5FI0 A;  3EO2 A;  1KI1 B;  1RJ2 A;  2NZ8 B;  2Z0Q A;  1BY1 A;  4YON A;  3ODO A;  4GZU A;  3QBV B;  2DFK A;  2VRW B;  3JV3 A;  1TXD A;  5JHG A;  5FI1 A;  1KZ7 A;  3GF9 A;  1NTY A;  1LB1 A;  4GOU A;  2PZ1 A;  3BJI A;  2DX1 A;  3T06 A;  1KZG A;  4D0O A;  4D0N B;  3KY9 A;  2KR9 A;  3KSY A;  2RGN B;  3P6A A;  5JHH A;  3MPX A;  1FOE A;  4GYV A;  1DBH A;  1XD4 A;  3ODW A;  1F5X A; 
#chains in the Genus database with same CATH topology
 1X86 A;  4MT7 A;  1XCG A;  3KZ1 A;  3ODX A;  5FI0 A;  3EO2 A;  1KI1 B;  1RJ2 A;  2NZ8 B;  2Z0Q A;  1BY1 A;  4YON A;  3ODO A;  4GZU A;  3QBV B;  2DFK A;  2VRW B;  3JV3 A;  1TXD A;  5JHG A;  5FI1 A;  1KZ7 A;  3GF9 A;  1NTY A;  1LB1 A;  4GOU A;  2PZ1 A;  3BJI A;  2DX1 A;  3T06 A;  1KZG A;  4D0O A;  4D0N B;  3KY9 A;  2KR9 A;  3KSY A;  2RGN B;  3P6A A;  5JHH A;  3MPX A;  1FOE A;  4GYV A;  1DBH A;  1XD4 A;  3ODW A;  1F5X A; 
#chains in the Genus database with same CATH homology
 1X86 A;  4MT7 A;  1XCG A;  3KZ1 A;  3ODX A;  5FI0 A;  3EO2 A;  1KI1 B;  1RJ2 A;  2NZ8 B;  2Z0Q A;  1BY1 A;  4YON A;  3ODO A;  4GZU A;  3QBV B;  2DFK A;  2VRW B;  3JV3 A;  1TXD A;  5JHG A;  5FI1 A;  1KZ7 A;  3GF9 A;  1NTY A;  1LB1 A;  4GOU A;  2PZ1 A;  3BJI A;  2DX1 A;  3T06 A;  1KZG A;  4D0O A;  4D0N B;  3KY9 A;  2KR9 A;  3KSY A;  2RGN B;  3P6A A;  5JHH A;  3MPX A;  1FOE A;  4GYV A;  1DBH A;  1XD4 A;  3ODW A;  1F5X A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2KR9A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations