2WZKA

Structure of the cul5 n-terminal domain at 2.05a resolution.
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
377
structure length
369
Chain Sequence
SLQFEDKWDFMHPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKAENL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords CULLIN-5
total genus 152
structure length 369
sequence length 377
ec nomenclature
pdb deposition date 2009-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA03
1LDKA 4WQOD 4P5OA 2WZKA 4APFB 1LDKB 1U6GA 1LDJA 4A64A 4EOZB 4JGHD 4F52A 4HXIB 3DQVC 4N9F3 3RTRA 4AP2B 3DPLC
chains in the Genus database with same CATH superfamily
5F3JA 2WAUA 3BQKA 4NUVA 4A64A 4F52A 2XU0A 4YFSA 3DPLC 4NUUA 1LDKA 4WQOD 4APFB 3BQIA 3DQVC 2B1EA 3RRCA 2PFVA 1LDKB 2Y8DA 3CPZA 4P5OA 2WZKA 1U6GA 1LDJA 4EOZB 4JGHD 3CMLA 4AP2B 4HXIB 4N9F3 3RTRA 3BQLA
chains in the Genus database with same CATH topology
1LDKA 4WQOD 4P5OA 2WZKA 4APFB 1LDKB 1U6GA 1LDJA 4A64A 4EOZB 4JGHD 4F52A 4HXIB 3DQVC 4N9F3 3RTRA 4AP2B 3DPLC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LDK A;  4WQO D;  4P5O A;  2WZK A;  4APF B;  1LDK B;  1U6G A;  1LDJ A;  4A64 A;  4EOZ B;  4JGH D;  4F52 A;  4HXI B;  3DQV C;  4N9F 3;  3RTR A;  4AP2 B;  3DPL C; 
#chains in the Genus database with same CATH topology
 5F3J A;  2WAU A;  3BQK A;  4NUV A;  4A64 A;  4F52 A;  2XU0 A;  4YFS A;  3DPL C;  4NUU A;  1LDK A;  4WQO D;  4APF B;  3BQI A;  3DQV C;  2B1E A;  3RRC A;  2PFV A;  1LDK B;  2Y8D A;  3CPZ A;  4P5O A;  2WZK A;  1U6G A;  1LDJ A;  4EOZ B;  4JGH D;  3CML A;  4AP2 B;  4HXI B;  4N9F 3;  3RTR A;  3BQL A; 
#chains in the Genus database with same CATH homology
 1LDK A;  4WQO D;  4P5O A;  2WZK A;  4APF B;  1LDK B;  1U6G A;  1LDJ A;  4A64 A;  4EOZ B;  4JGH D;  4F52 A;  4HXI B;  3DQV C;  4N9F 3;  3RTR A;  4AP2 B;  3DPL C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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