2WZKA

Structure of the cul5 n-terminal domain at 2.05a resolution.
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
377
structure length
369
Chain Sequence
SLQFEDKWDFMHPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKAENL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords CULLIN-5
total genus 152
structure length 369
sequence length 377
ec nomenclature
pdb deposition date 2009-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA03
4APFB 3DQVC 4EOZB 2WZKA 4HXIB 4JGHD 4F52A 4WQOD 3RTRA 1U6GA 4A64A 3DPLC 4P5OA 1LDKB 4N9F3 4AP2B 1LDJA 1LDKA
chains in the Genus database with same CATH superfamily
2Y8DA 4NUUA 3CPZA 3BQLA 3DPLC 2WAUA 2PFVA 3CMLA 3RRCA 2WZKA 3BQIA 1U6GA 4YFSA 4A64A 1LDKB 4AP2B 5F3JA 1LDKA 4APFB 4EOZB 4HXIB 4JGHD 4F52A 2B1EA 4WQOD 4P5OA 4NUVA 1LDJA 3BQKA 3RTRA 3DQVC 2XU0A 4N9F3
chains in the Genus database with same CATH topology
4APFB 3DQVC 4EOZB 2WZKA 4HXIB 4JGHD 4F52A 4WQOD 3RTRA 1U6GA 4A64A 3DPLC 4P5OA 1LDKB 4N9F3 4AP2B 1LDJA 1LDKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4APF B;  3DQV C;  4EOZ B;  2WZK A;  4HXI B;  4JGH D;  4F52 A;  4WQO D;  3RTR A;  1U6G A;  4A64 A;  3DPL C;  4P5O A;  1LDK B;  4N9F 3;  4AP2 B;  1LDJ A;  1LDK A; 
#chains in the Genus database with same CATH topology
 2Y8D A;  4NUU A;  3CPZ A;  3BQL A;  3DPL C;  2WAU A;  2PFV A;  3CML A;  3RRC A;  2WZK A;  3BQI A;  1U6G A;  4YFS A;  4A64 A;  1LDK B;  4AP2 B;  5F3J A;  1LDK A;  4APF B;  4EOZ B;  4HXI B;  4JGH D;  4F52 A;  2B1E A;  4WQO D;  4P5O A;  4NUV A;  1LDJ A;  3BQK A;  3RTR A;  3DQV C;  2XU0 A;  4N9F 3; 
#chains in the Genus database with same CATH homology
 4APF B;  3DQV C;  4EOZ B;  2WZK A;  4HXI B;  4JGH D;  4F52 A;  4WQO D;  3RTR A;  1U6G A;  4A64 A;  3DPL C;  4P5O A;  1LDK B;  4N9F 3;  4AP2 B;  1LDJ A;  1LDK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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