2WZKA

Structure of the cul5 n-terminal domain at 2.05a resolution.
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
377
structure length
369
Chain Sequence
SLQFEDKWDFMHPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKAENL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
pubmed doi rcsb
molecule keywords CULLIN-5
molecule tags Protein binding
source organism Mus musculus
total genus 152
structure length 369
sequence length 377
ec nomenclature
pdb deposition date 2009-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA03
4HXIB 3DQVC 4JGHD 3RTRA 4APFB 4P5OA 4N9F3 2WZKA 1U6GA 3DPLC 4WQOD 4AP2B 4EOZB 4F52A 4A64A 1LDKA 1LDJA 1LDKB
chains in the Genus database with same CATH superfamily
4JGHD 3CMLA 4APFB 3DPLC 4WQOD 1LDKA 4P5OA 4YFSA 4N9F3 2WZKA 1U6GA 3BQIA 2WAUA 5F3JA 2Y8DA 1LDKB 4HXIB 3DQVC 3BQKA 4NUUA 3BQLA 4EOZB 4F52A 4A64A 4NUVA 2XU0A 2B1EA 3RTRA 2PFVA 4AP2B 3RRCA 3CPZA 1LDJA
chains in the Genus database with same CATH topology
4HXIB 3DQVC 4JGHD 3RTRA 4APFB 4P5OA 4N9F3 2WZKA 1U6GA 3DPLC 4WQOD 4AP2B 4EOZB 4F52A 4A64A 1LDKA 1LDJA 1LDKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HXI B;  3DQV C;  4JGH D;  3RTR A;  4APF B;  4P5O A;  4N9F 3;  2WZK A;  1U6G A;  3DPL C;  4WQO D;  4AP2 B;  4EOZ B;  4F52 A;  4A64 A;  1LDK A;  1LDJ A;  1LDK B; 
#chains in the Genus database with same CATH topology
 4JGH D;  3CML A;  4APF B;  3DPL C;  4WQO D;  1LDK A;  4P5O A;  4YFS A;  4N9F 3;  2WZK A;  1U6G A;  3BQI A;  2WAU A;  5F3J A;  2Y8D A;  1LDK B;  4HXI B;  3DQV C;  3BQK A;  4NUU A;  3BQL A;  4EOZ B;  4F52 A;  4A64 A;  4NUV A;  2XU0 A;  2B1E A;  3RTR A;  2PFV A;  4AP2 B;  3RRC A;  3CPZ A;  1LDJ A; 
#chains in the Genus database with same CATH homology
 4HXI B;  3DQV C;  4JGH D;  3RTR A;  4APF B;  4P5O A;  4N9F 3;  2WZK A;  1U6G A;  3DPL C;  4WQO D;  4AP2 B;  4EOZ B;  4F52 A;  4A64 A;  1LDK A;  1LDJ A;  1LDK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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