2WZKA

Structure of the cul5 n-terminal domain at 2.05a resolution.
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
377
structure length
369
Chain Sequence
SLQFEDKWDFMHPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKAENL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Mus musculus
publication title Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
pubmed doi rcsb
molecule keywords CULLIN-5
total genus 152
structure length 369
sequence length 377
ec nomenclature
pdb deposition date 2009-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA03
4N9F3 1LDJA 4JGHD 4HXIB 2WZKA 4WQOD 3RTRA 4APFB 3DQVC 1U6GA 4F52A 4A64A 4AP2B 1LDKB 1LDKA 4EOZB 3DPLC 4P5OA
chains in the Genus database with same CATH superfamily
2XU0A 4APFB 2PFVA 4YFSA 3CPZA 3DPLC 4NUVA 1LDJA 4HXIB 3RRCA 4NUUA 4A64A 1LDKA 4N9F3 4JGHD 2WZKA 2Y8DA 3DQVC 2B1EA 1LDKB 4WQOD 4EOZB 3BQLA 3BQIA 4P5OA 5F3JA 3RTRA 1U6GA 2WAUA 3BQKA 4AP2B 3CMLA 4F52A
chains in the Genus database with same CATH topology
4N9F3 1LDJA 4JGHD 4HXIB 2WZKA 4WQOD 3RTRA 4APFB 3DQVC 1U6GA 4F52A 4A64A 4AP2B 1LDKB 1LDKA 4EOZB 3DPLC 4P5OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N9F 3;  1LDJ A;  4JGH D;  4HXI B;  2WZK A;  4WQO D;  3RTR A;  4APF B;  3DQV C;  1U6G A;  4F52 A;  4A64 A;  4AP2 B;  1LDK B;  1LDK A;  4EOZ B;  3DPL C;  4P5O A; 
#chains in the Genus database with same CATH topology
 2XU0 A;  4APF B;  2PFV A;  4YFS A;  3CPZ A;  3DPL C;  4NUV A;  1LDJ A;  4HXI B;  3RRC A;  4NUU A;  4A64 A;  1LDK A;  4N9F 3;  4JGH D;  2WZK A;  2Y8D A;  3DQV C;  2B1E A;  1LDK B;  4WQO D;  4EOZ B;  3BQL A;  3BQI A;  4P5O A;  5F3J A;  3RTR A;  1U6G A;  2WAU A;  3BQK A;  4AP2 B;  3CML A;  4F52 A; 
#chains in the Genus database with same CATH homology
 4N9F 3;  1LDJ A;  4JGH D;  4HXI B;  2WZK A;  4WQO D;  3RTR A;  4APF B;  3DQV C;  1U6G A;  4F52 A;  4A64 A;  4AP2 B;  1LDK B;  1LDK A;  4EOZ B;  3DPL C;  4P5O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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