4JGHD

Structure of the socs2-elongin bc complex bound to an n-terminal fragment of cullin5
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
378
structure length
368
Chain Sequence
KGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Suppressor of cytokine signaling 2
publication title Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
pubmed doi rcsb
source organism Homo sapiens
total genus 135
structure length 368
sequence length 378
ec nomenclature
pdb deposition date 2013-03-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD03
1LDKB 4HXIB 4N9F3 4AP2B 4F52A 4WQOD 1U6GA 1LDJA 2WZKA 4JGHD 4EOZB 4A64A 4P5OA 1LDKA 4APFB 3DQVC 3DPLC 3RTRA
chains in the Genus database with same CATH superfamily
4NUVA 2WAUA 4WQOD 3BQLA 4JGHD 3RRCA 4P5OA 4YFSA 4NUUA 5F3JA 3BQKA 4HXIB 4AP2B 2XU0A 1LDKA 3RTRA 1LDKB 3BQIA 4EOZB 2WZKA 4A64A 4APFB 2Y8DA 3DPLC 2B1EA 4N9F3 4F52A 1U6GA 1LDJA 2PFVA 3CPZA 3DQVC 3CMLA
chains in the Genus database with same CATH topology
1LDKB 4HXIB 4N9F3 4AP2B 4F52A 4WQOD 1U6GA 1LDJA 2WZKA 4JGHD 4EOZB 4A64A 4P5OA 1LDKA 4APFB 3DQVC 3DPLC 3RTRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LDK B;  4HXI B;  4N9F 3;  4AP2 B;  4F52 A;  4WQO D;  1U6G A;  1LDJ A;  2WZK A;  4JGH D;  4EOZ B;  4A64 A;  4P5O A;  1LDK A;  4APF B;  3DQV C;  3DPL C;  3RTR A; 
#chains in the Genus database with same CATH topology
 4NUV A;  2WAU A;  4WQO D;  3BQL A;  4JGH D;  3RRC A;  4P5O A;  4YFS A;  4NUU A;  5F3J A;  3BQK A;  4HXI B;  4AP2 B;  2XU0 A;  1LDK A;  3RTR A;  1LDK B;  3BQI A;  4EOZ B;  2WZK A;  4A64 A;  4APF B;  2Y8D A;  3DPL C;  2B1E A;  4N9F 3;  4F52 A;  1U6G A;  1LDJ A;  2PFV A;  3CPZ A;  3DQV C;  3CML A; 
#chains in the Genus database with same CATH homology
 1LDK B;  4HXI B;  4N9F 3;  4AP2 B;  4F52 A;  4WQO D;  1U6G A;  1LDJ A;  2WZK A;  4JGH D;  4EOZ B;  4A64 A;  4P5O A;  1LDK A;  4APF B;  3DQV C;  3DPL C;  3RTR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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