4N9F3

Crystal structure of the vif-cbfbeta-cul5-elob-eloc pentameric complex
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
309
structure length
295
Chain Sequence
ASLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase/viral protein
molecule keywords Cullin-5
publication title Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif
rcsb
source organism Homo sapiens
total genus 102
structure length 295
sequence length 309
chains with identical sequence 9, C, I, O, U, V, f, l, r, w, x
ec nomenclature
pdb deposition date 2013-10-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4n9f301
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4n9f302
1LDKA 4JGHD 4F52A 1LDJA 1U6GA 3RTRA 1LDKB 4APFB 4AP2B 4HXIB 4A64A 3DPLC 4WQOD 4EOZB 3DQVC 4N9F3 2WZKA 4P5OA
chains in the Genus database with same CATH superfamily
1LDKA 2B1EA 3BQIA 1LDJA 3DPLC 3DQVC 3CPZA 2WZKA 4F52A 3CMLA 1U6GA 3BQKA 2PFVA 4YFSA 4A64A 4WQOD 4P5OA 4JGHD 5F3JA 4HXIB 3RRCA 4EOZB 2XU0A 3RTRA 4NUVA 4APFB 1LDKB 4AP2B 2Y8DA 2WAUA 3BQLA 4NUUA 4N9F3
chains in the Genus database with same CATH topology
1LDKA 4JGHD 4F52A 1LDJA 1U6GA 3RTRA 1LDKB 4APFB 4AP2B 4HXIB 4A64A 3DPLC 4WQOD 4EOZB 3DQVC 4N9F3 2WZKA 4P5OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LDK A;  4JGH D;  4F52 A;  1LDJ A;  1U6G A;  3RTR A;  1LDK B;  4APF B;  4AP2 B;  4HXI B;  4A64 A;  3DPL C;  4WQO D;  4EOZ B;  3DQV C;  4N9F 3;  2WZK A;  4P5O A; 
#chains in the Genus database with same CATH topology
 1LDK A;  2B1E A;  3BQI A;  1LDJ A;  3DPL C;  3DQV C;  3CPZ A;  2WZK A;  4F52 A;  3CML A;  1U6G A;  3BQK A;  2PFV A;  4YFS A;  4A64 A;  4WQO D;  4P5O A;  4JGH D;  5F3J A;  4HXI B;  3RRC A;  4EOZ B;  2XU0 A;  3RTR A;  4NUV A;  4APF B;  1LDK B;  4AP2 B;  2Y8D A;  2WAU A;  3BQL A;  4NUU A;  4N9F 3; 
#chains in the Genus database with same CATH homology
 1LDK A;  4JGH D;  4F52 A;  1LDJ A;  1U6G A;  3RTR A;  1LDK B;  4APF B;  4AP2 B;  4HXI B;  4A64 A;  3DPL C;  4WQO D;  4EOZ B;  3DQV C;  4N9F 3;  2WZK A;  4P5O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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