2XU0A

Crystal structure of the nts-dbl1(alpha-1) domain of the plasmodium falciparum membrane protein 1 (pfemp1) from the varo strain.
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
476
structure length
447
Chain Sequence
SPTLSESHKSARNVLENIGIKIYNQEIKKKNPYEQQLKGTLDGNSCNLDHLFGRKPCYGREQNRFDENAEAYCNSDKIRGNENNANGAACAPPRRRHICDQNLEFLDNKNTNTAHDLLGNVLVTAKYEGNYIVNDHPDKNSNGNKAGICTSLARSFADIGDIVRGRDMFLPNKDDKVQKGLQVVFKKIYKSLTPEARKHYAHGDGSGNYAKLREDWWTINREQIWKALTCSAPYYADYFRKGSDGTLHFSSHGKCGHNEGAPPTYLDYVPQFLRWFEEWSEEFCRIKKIKIDKVKKECRDEQNKKYCSGDGHDCTQTNLAHNQIFVDLDCPRCQDQCIKYNEWIVKKLEEFYKQNLKYSMEIQKWKKTKNNYYDKEFYENLDKKSYSTIDKFLNLLNNGKHCHDNKDEKNKIDFNKPIKTFSISEYCKTCPLYGVTCTNRGICIHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein
source organism Plasmodium falciparum palo alto/uganda
publication title Structure of a Plasmodium Falciparum Pfemp1 Rosetting Domain Reveals a Role for the N-Terminal Segment in Heparin-Mediated Rosette Inhibition.
pubmed doi rcsb
molecule keywords ERYTHROCYTE MEMBRANE PROTEIN 1
total genus 169
structure length 447
sequence length 476
ec nomenclature
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05424 Duffy_binding Duffy binding domain
A PF15447 NTS N-terminal segments of PfEMP1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.20 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like 5 helical Cullin repeat like 2xu0A00
3CMLA 2Y8DA 4YFSA 3RRCA 4NUUA 5F3JA 2WAUA 2XU0A 3CPZA 3BQLA 4NUVA 3BQIA 3BQKA
chains in the Genus database with same CATH superfamily
1U6GA 3DQVC 3CPZA 3BQKA 4YFSA 3RRCA 4F52A 4WQOD 1LDKA 3BQLA 1LDJA 4P5OA 3CMLA 4A64A 3RTRA 1LDKB 4APFB 2PFVA 4EOZB 2WZKA 4HXIB 2WAUA 4N9F3 4NUVA 3BQIA 2Y8DA 5F3JA 2B1EA 2XU0A 4JGHD 4AP2B 3DPLC 4NUUA
chains in the Genus database with same CATH topology
3CMLA 2Y8DA 4YFSA 2PFVA 3RRCA 4NUUA 5F3JA 2WAUA 2B1EA 2XU0A 3CPZA 3BQLA 4NUVA 3BQIA 3BQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CML A;  2Y8D A;  4YFS A;  3RRC A;  4NUU A;  5F3J A;  2WAU A;  2XU0 A;  3CPZ A;  3BQL A;  4NUV A;  3BQI A;  3BQK A; 
#chains in the Genus database with same CATH topology
 1U6G A;  3DQV C;  3CPZ A;  3BQK A;  4YFS A;  3RRC A;  4F52 A;  4WQO D;  1LDK A;  3BQL A;  1LDJ A;  4P5O A;  3CML A;  4A64 A;  3RTR A;  1LDK B;  4APF B;  2PFV A;  4EOZ B;  2WZK A;  4HXI B;  2WAU A;  4N9F 3;  4NUV A;  3BQI A;  2Y8D A;  5F3J A;  2B1E A;  2XU0 A;  4JGH D;  4AP2 B;  3DPL C;  4NUU A; 
#chains in the Genus database with same CATH homology
 3CML A;  2Y8D A;  4YFS A;  2PFV A;  3RRC A;  4NUU A;  5F3J A;  2WAU A;  2B1E A;  2XU0 A;  3CPZ A;  3BQL A;  4NUV A;  3BQI A;  3BQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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