3EO2A

Crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
187
structure length
187
Chain Sequence
LTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein
rcsb
molecule tags Splicing
source organism Homo sapiens
molecule keywords Neuroepithelial cell-transforming gene 1 protein
total genus 75
structure length 187
sequence length 187
ec nomenclature
pdb deposition date 2008-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3eo2A00
3QBVB 4YONA 2NZ8B 3ODWA 5JHHA 1X86A 3JV3A 1TXDA 1DBHA 2PZ1A 1KZGA 3BJIA 4GOUA 4GZUA 2DX1A 5JHGA 1NTYA 1BY1A 3MPXA 4GYVA 1RJ2A 2Z0QA 5FI1A 3P6AA 5FI0A 1FOEA 3ODXA 1XD4A 4MT7A 4D0NB 1KI1B 2VRWB 3EO2A 3GF9A 3T06A 1F5XA 3KY9A 3KSYA 4D0OA 1KZ7A 2KR9A 3ODOA 2DFKA 2RGNB 1LB1A 3KZ1A 1XCGA
chains in the Genus database with same CATH superfamily
3QBVB 4YONA 2NZ8B 3ODWA 5JHHA 1X86A 3JV3A 1TXDA 1DBHA 2PZ1A 1KZGA 3BJIA 4GOUA 4GZUA 2DX1A 5JHGA 1NTYA 1BY1A 3MPXA 4GYVA 1RJ2A 2Z0QA 5FI1A 3P6AA 5FI0A 1FOEA 3ODXA 1XD4A 4MT7A 4D0NB 1KI1B 2VRWB 3EO2A 3GF9A 3T06A 1F5XA 3KY9A 3KSYA 4D0OA 1KZ7A 2KR9A 3ODOA 2DFKA 2RGNB 1LB1A 3KZ1A 1XCGA
chains in the Genus database with same CATH topology
3QBVB 4YONA 2NZ8B 3ODWA 5JHHA 1X86A 3JV3A 1TXDA 1DBHA 2PZ1A 1KZGA 3BJIA 4GOUA 4GZUA 2DX1A 5JHGA 1NTYA 1BY1A 3MPXA 4GYVA 1RJ2A 2Z0QA 5FI1A 3P6AA 5FI0A 1FOEA 3ODXA 1XD4A 4MT7A 4D0NB 1KI1B 2VRWB 3EO2A 3GF9A 3T06A 1F5XA 3KY9A 3KSYA 4D0OA 1KZ7A 2KR9A 3ODOA 2DFKA 2RGNB 1LB1A 3KZ1A 1XCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QBV B;  4YON A;  2NZ8 B;  3ODW A;  5JHH A;  1X86 A;  3JV3 A;  1TXD A;  1DBH A;  2PZ1 A;  1KZG A;  3BJI A;  4GOU A;  4GZU A;  2DX1 A;  5JHG A;  1NTY A;  1BY1 A;  3MPX A;  4GYV A;  1RJ2 A;  2Z0Q A;  5FI1 A;  3P6A A;  5FI0 A;  1FOE A;  3ODX A;  1XD4 A;  4MT7 A;  4D0N B;  1KI1 B;  2VRW B;  3EO2 A;  3GF9 A;  3T06 A;  1F5X A;  3KY9 A;  3KSY A;  4D0O A;  1KZ7 A;  2KR9 A;  3ODO A;  2DFK A;  2RGN B;  1LB1 A;  3KZ1 A;  1XCG A; 
#chains in the Genus database with same CATH topology
 3QBV B;  4YON A;  2NZ8 B;  3ODW A;  5JHH A;  1X86 A;  3JV3 A;  1TXD A;  1DBH A;  2PZ1 A;  1KZG A;  3BJI A;  4GOU A;  4GZU A;  2DX1 A;  5JHG A;  1NTY A;  1BY1 A;  3MPX A;  4GYV A;  1RJ2 A;  2Z0Q A;  5FI1 A;  3P6A A;  5FI0 A;  1FOE A;  3ODX A;  1XD4 A;  4MT7 A;  4D0N B;  1KI1 B;  2VRW B;  3EO2 A;  3GF9 A;  3T06 A;  1F5X A;  3KY9 A;  3KSY A;  4D0O A;  1KZ7 A;  2KR9 A;  3ODO A;  2DFK A;  2RGN B;  1LB1 A;  3KZ1 A;  1XCG A; 
#chains in the Genus database with same CATH homology
 3QBV B;  4YON A;  2NZ8 B;  3ODW A;  5JHH A;  1X86 A;  3JV3 A;  1TXD A;  1DBH A;  2PZ1 A;  1KZG A;  3BJI A;  4GOU A;  4GZU A;  2DX1 A;  5JHG A;  1NTY A;  1BY1 A;  3MPX A;  4GYV A;  1RJ2 A;  2Z0Q A;  5FI1 A;  3P6A A;  5FI0 A;  1FOE A;  3ODX A;  1XD4 A;  4MT7 A;  4D0N B;  1KI1 B;  2VRW B;  3EO2 A;  3GF9 A;  3T06 A;  1F5X A;  3KY9 A;  3KSY A;  4D0O A;  1KZ7 A;  2KR9 A;  3ODO A;  2DFK A;  2RGN B;  1LB1 A;  3KZ1 A;  1XCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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