3EO2 | Genus

Total Genus 75

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	75
sequence length	187
structure length	187
Chain Sequence	LTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDIN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Splicing
source organism	Homo sapiens
publication title	Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein rcsb
molecule keywords	Neuroepithelial cell-transforming gene 1 protein
total genus	75
structure length	187
sequence length	187
ec nomenclature
pdb deposition date	2008-09-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	3eo2A00

1DBHA 3GF9A 3KZ1A 3T06A 3KY9A 2PZ1A 4GZUA 5JHGA 1KZ7A 3EO2A 4GYVA 4MT7A 3JV3A 4GOUA 2NZ8B 1XD4A 3MPXA 2RGNB 2VRWB 1KZGA 4D0NB 4D0OA 1KI1B 2DFKA 5FI1A 2KR9A 2Z0QA 1RJ2A 5FI0A 1FOEA 3P6AA 3ODXA 1XCGA 3QBVB 5JHHA 1BY1A 1LB1A 2DX1A 1TXDA 3ODWA 4YONA 3BJIA 1X86A 1NTYA 3ODOA 1F5XA 3KSYA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1DBH A;  3GF9 A;  3KZ1 A;  3T06 A;  3KY9 A;  2PZ1 A;  4GZU A;  5JHG A;  1KZ7 A;  3EO2 A;  4GYV A;  4MT7 A;  3JV3 A;  4GOU A;  2NZ8 B;  1XD4 A;  3MPX A;  2RGN B;  2VRW B;  1KZG A;  4D0N B;  4D0O A;  1KI1 B;  2DFK A;  5FI1 A;  2KR9 A;  2Z0Q A;  1RJ2 A;  5FI0 A;  1FOE A;  3P6A A;  3ODX A;  1XCG A;  3QBV B;  5JHH A;  1BY1 A;  1LB1 A;  2DX1 A;  1TXD A;  3ODW A;  4YON A;  3BJI A;  1X86 A;  1NTY A;  3ODO A;  1F5X A;  3KSY A; 
#chains in the Genus database with same CATH topology
 1DBH A;  3GF9 A;  3KZ1 A;  3T06 A;  3KY9 A;  2PZ1 A;  4GZU A;  5JHG A;  1KZ7 A;  3EO2 A;  4GYV A;  4MT7 A;  3JV3 A;  4GOU A;  2NZ8 B;  1XD4 A;  3MPX A;  2RGN B;  2VRW B;  1KZG A;  4D0N B;  4D0O A;  1KI1 B;  2DFK A;  5FI1 A;  2KR9 A;  2Z0Q A;  1RJ2 A;  5FI0 A;  1FOE A;  3P6A A;  3ODX A;  1XCG A;  3QBV B;  5JHH A;  1BY1 A;  1LB1 A;  2DX1 A;  1TXD A;  3ODW A;  4YON A;  3BJI A;  1X86 A;  1NTY A;  3ODO A;  1F5X A;  3KSY A; 
#chains in the Genus database with same CATH homology
 1DBH A;  3GF9 A;  3KZ1 A;  3T06 A;  3KY9 A;  2PZ1 A;  4GZU A;  5JHG A;  1KZ7 A;  3EO2 A;  4GYV A;  4MT7 A;  3JV3 A;  4GOU A;  2NZ8 B;  1XD4 A;  3MPX A;  2RGN B;  2VRW B;  1KZG A;  4D0N B;  4D0O A;  1KI1 B;  2DFK A;  5FI1 A;  2KR9 A;  2Z0Q A;  1RJ2 A;  5FI0 A;  1FOE A;  3P6A A;  3ODX A;  1XCG A;  3QBV B;  5JHH A;  1BY1 A;  1LB1 A;  2DX1 A;  1TXD A;  3ODW A;  4YON A;  3BJI A;  1X86 A;  1NTY A;  3ODO A;  1F5X A;  3KSY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3EO2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations