3EO2A

Crystal structure of the rhogef domain of human neuroepithelial cell-transforming gene 1 protein
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
187
structure length
187
Chain Sequence
LTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Splicing
source organism Homo sapiens
publication title Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein
rcsb
molecule keywords Neuroepithelial cell-transforming gene 1 protein
total genus 75
structure length 187
sequence length 187
ec nomenclature
pdb deposition date 2008-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3eo2A00
1LB1A 3JV3A 1NTYA 3QBVB 4YONA 3MPXA 2PZ1A 5FI0A 4D0OA 5JHHA 2DX1A 2KR9A 1XCGA 3KY9A 4GZUA 1KZ7A 3ODWA 2VRWB 1DBHA 3BJIA 3KZ1A 4GOUA 2Z0QA 3ODXA 5FI1A 1KI1B 1TXDA 3T06A 1KZGA 5JHGA 3ODOA 1F5XA 3GF9A 2NZ8B 2DFKA 3P6AA 1X86A 2RGNB 4GYVA 3EO2A 4MT7A 3KSYA 4D0NB 1XD4A 1BY1A 1FOEA 1RJ2A
chains in the Genus database with same CATH superfamily
1LB1A 3JV3A 1NTYA 3QBVB 4YONA 3MPXA 2PZ1A 5FI0A 4D0OA 5JHHA 2DX1A 2KR9A 1XCGA 3KY9A 4GZUA 1KZ7A 3ODWA 2VRWB 1DBHA 3BJIA 3KZ1A 4GOUA 2Z0QA 3ODXA 5FI1A 1KI1B 1TXDA 3T06A 1KZGA 5JHGA 3ODOA 1F5XA 3GF9A 2NZ8B 2DFKA 3P6AA 1X86A 2RGNB 4GYVA 3EO2A 4MT7A 3KSYA 4D0NB 1XD4A 1BY1A 1FOEA 1RJ2A
chains in the Genus database with same CATH topology
1LB1A 3JV3A 1NTYA 3QBVB 4YONA 3MPXA 2PZ1A 5FI0A 4D0OA 5JHHA 2DX1A 2KR9A 1XCGA 3KY9A 4GZUA 1KZ7A 3ODWA 2VRWB 1DBHA 3BJIA 3KZ1A 4GOUA 2Z0QA 3ODXA 5FI1A 1KI1B 1TXDA 3T06A 1KZGA 5JHGA 3ODOA 1F5XA 3GF9A 2NZ8B 2DFKA 3P6AA 1X86A 2RGNB 4GYVA 3EO2A 4MT7A 3KSYA 4D0NB 1XD4A 1BY1A 1FOEA 1RJ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LB1 A;  3JV3 A;  1NTY A;  3QBV B;  4YON A;  3MPX A;  2PZ1 A;  5FI0 A;  4D0O A;  5JHH A;  2DX1 A;  2KR9 A;  1XCG A;  3KY9 A;  4GZU A;  1KZ7 A;  3ODW A;  2VRW B;  1DBH A;  3BJI A;  3KZ1 A;  4GOU A;  2Z0Q A;  3ODX A;  5FI1 A;  1KI1 B;  1TXD A;  3T06 A;  1KZG A;  5JHG A;  3ODO A;  1F5X A;  3GF9 A;  2NZ8 B;  2DFK A;  3P6A A;  1X86 A;  2RGN B;  4GYV A;  3EO2 A;  4MT7 A;  3KSY A;  4D0N B;  1XD4 A;  1BY1 A;  1FOE A;  1RJ2 A; 
#chains in the Genus database with same CATH topology
 1LB1 A;  3JV3 A;  1NTY A;  3QBV B;  4YON A;  3MPX A;  2PZ1 A;  5FI0 A;  4D0O A;  5JHH A;  2DX1 A;  2KR9 A;  1XCG A;  3KY9 A;  4GZU A;  1KZ7 A;  3ODW A;  2VRW B;  1DBH A;  3BJI A;  3KZ1 A;  4GOU A;  2Z0Q A;  3ODX A;  5FI1 A;  1KI1 B;  1TXD A;  3T06 A;  1KZG A;  5JHG A;  3ODO A;  1F5X A;  3GF9 A;  2NZ8 B;  2DFK A;  3P6A A;  1X86 A;  2RGN B;  4GYV A;  3EO2 A;  4MT7 A;  3KSY A;  4D0N B;  1XD4 A;  1BY1 A;  1FOE A;  1RJ2 A; 
#chains in the Genus database with same CATH homology
 1LB1 A;  3JV3 A;  1NTY A;  3QBV B;  4YON A;  3MPX A;  2PZ1 A;  5FI0 A;  4D0O A;  5JHH A;  2DX1 A;  2KR9 A;  1XCG A;  3KY9 A;  4GZU A;  1KZ7 A;  3ODW A;  2VRW B;  1DBH A;  3BJI A;  3KZ1 A;  4GOU A;  2Z0Q A;  3ODX A;  5FI1 A;  1KI1 B;  1TXD A;  3T06 A;  1KZG A;  5JHG A;  3ODO A;  1F5X A;  3GF9 A;  2NZ8 B;  2DFK A;  3P6A A;  1X86 A;  2RGN B;  4GYV A;  3EO2 A;  4MT7 A;  3KSY A;  4D0N B;  1XD4 A;  1BY1 A;  1FOE A;  1RJ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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