3GF9A

Crystal structure of human intersectin 2 rhogef domain
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
190
structure length
182
Chain Sequence
IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of human Intersectin 2 RhoGEF domain
rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Intersectin 2
total genus 79
structure length 182
sequence length 190
ec nomenclature
pdb deposition date 2009-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
A PF14604 SH3_9 Variant SH3 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3gf9A00
2VRWB 4YONA 2PZ1A 1KI1B 4GYVA 4D0NB 3ODOA 4D0OA 1X86A 3BJIA 3EO2A 3MPXA 1KZ7A 1XCGA 3KZ1A 1KZGA 1BY1A 2NZ8B 2KR9A 2Z0QA 4MT7A 3JV3A 5FI0A 1NTYA 5FI1A 5JHHA 3GF9A 3KY9A 2DX1A 1RJ2A 1XD4A 3KSYA 5JHGA 4GOUA 2RGNB 1LB1A 2DFKA 1F5XA 3T06A 1TXDA 3ODXA 1FOEA 1DBHA 3P6AA 3QBVB 3ODWA 4GZUA
chains in the Genus database with same CATH superfamily
2VRWB 4YONA 2PZ1A 1KI1B 4GYVA 4D0NB 3ODOA 4D0OA 1X86A 3BJIA 3EO2A 3MPXA 1KZ7A 1XCGA 3KZ1A 1KZGA 1BY1A 2NZ8B 2KR9A 2Z0QA 4MT7A 3JV3A 5FI0A 1NTYA 5FI1A 5JHHA 3GF9A 3KY9A 2DX1A 1RJ2A 1XD4A 3KSYA 5JHGA 4GOUA 2RGNB 1LB1A 2DFKA 1F5XA 3T06A 1TXDA 3ODXA 1FOEA 1DBHA 3P6AA 3QBVB 3ODWA 4GZUA
chains in the Genus database with same CATH topology
2VRWB 4YONA 2PZ1A 1KI1B 4GYVA 4D0NB 3ODOA 4D0OA 1X86A 3BJIA 3EO2A 3MPXA 1KZ7A 1XCGA 3KZ1A 1KZGA 1BY1A 2NZ8B 2KR9A 2Z0QA 4MT7A 3JV3A 5FI0A 1NTYA 5FI1A 5JHHA 3GF9A 3KY9A 2DX1A 1RJ2A 1XD4A 3KSYA 5JHGA 4GOUA 2RGNB 1LB1A 2DFKA 1F5XA 3T06A 1TXDA 3ODXA 1FOEA 1DBHA 3P6AA 3QBVB 3ODWA 4GZUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VRW B;  4YON A;  2PZ1 A;  1KI1 B;  4GYV A;  4D0N B;  3ODO A;  4D0O A;  1X86 A;  3BJI A;  3EO2 A;  3MPX A;  1KZ7 A;  1XCG A;  3KZ1 A;  1KZG A;  1BY1 A;  2NZ8 B;  2KR9 A;  2Z0Q A;  4MT7 A;  3JV3 A;  5FI0 A;  1NTY A;  5FI1 A;  5JHH A;  3GF9 A;  3KY9 A;  2DX1 A;  1RJ2 A;  1XD4 A;  3KSY A;  5JHG A;  4GOU A;  2RGN B;  1LB1 A;  2DFK A;  1F5X A;  3T06 A;  1TXD A;  3ODX A;  1FOE A;  1DBH A;  3P6A A;  3QBV B;  3ODW A;  4GZU A; 
#chains in the Genus database with same CATH topology
 2VRW B;  4YON A;  2PZ1 A;  1KI1 B;  4GYV A;  4D0N B;  3ODO A;  4D0O A;  1X86 A;  3BJI A;  3EO2 A;  3MPX A;  1KZ7 A;  1XCG A;  3KZ1 A;  1KZG A;  1BY1 A;  2NZ8 B;  2KR9 A;  2Z0Q A;  4MT7 A;  3JV3 A;  5FI0 A;  1NTY A;  5FI1 A;  5JHH A;  3GF9 A;  3KY9 A;  2DX1 A;  1RJ2 A;  1XD4 A;  3KSY A;  5JHG A;  4GOU A;  2RGN B;  1LB1 A;  2DFK A;  1F5X A;  3T06 A;  1TXD A;  3ODX A;  1FOE A;  1DBH A;  3P6A A;  3QBV B;  3ODW A;  4GZU A; 
#chains in the Genus database with same CATH homology
 2VRW B;  4YON A;  2PZ1 A;  1KI1 B;  4GYV A;  4D0N B;  3ODO A;  4D0O A;  1X86 A;  3BJI A;  3EO2 A;  3MPX A;  1KZ7 A;  1XCG A;  3KZ1 A;  1KZG A;  1BY1 A;  2NZ8 B;  2KR9 A;  2Z0Q A;  4MT7 A;  3JV3 A;  5FI0 A;  1NTY A;  5FI1 A;  5JHH A;  3GF9 A;  3KY9 A;  2DX1 A;  1RJ2 A;  1XD4 A;  3KSY A;  5JHG A;  4GOU A;  2RGN B;  1LB1 A;  2DFK A;  1F5X A;  3T06 A;  1TXD A;  3ODX A;  1FOE A;  1DBH A;  3P6A A;  3QBV B;  3ODW A;  4GZU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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