3I50E

Crystal structure of the west nile virus envelope glycoprotein in complex with the e53 antibody fab
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
291
structure length
273
Chain Sequence
SNRDFLEGVSGATWVDLVLEGDSCVTIMSKDKPTIDVKMMNMEAANLAEVRSYCYLATVSDLSTKAACPTMGEAHNDKRADPAFVCRQGVVDRGWGNGCGLFGKGSIDTCAKFACSTKAIGRTILKENIKYEVAIFVHQAGRFSITPAAPSYTLKLGEYGEVTVDCEPRSGIDTNAYYVMTVGTKTFLVHREWFMDLNLPWSSAGSTVWRNRETLMEFEEPHATKQSVIALGSQEGALHQALAGAIPVEFSSNTVKLTSGHLKCRVKMEKLQL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism West nile virus
molecule keywords Envelope glycoprotein
total genus 40
structure length 273
sequence length 291
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2009-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00869 Flavi_glycoprot Flavivirus glycoprotein, central and dimerisation domains
E PF02832 Flavi_glycop_C Flavivirus glycoprotein, immunoglobulin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.98.10 Mainly Beta Sandwich Tick-borne Encephalitis virus Glycoprotein; domain 1 Tick-borne Encephalitis virus Glycoprotein, domain 1 3i50E00
4GSXA 1OK8A 1OANA 3N40F 2ALAA 4FG0A 3N41F 3UAJA 3G7TA 5IZ7A 1SVBA 5LBVA 5JHLA 4UT6A 3C6EA 5GZOA 3N43F 5JHMA 1TG8A 3C5XA 4UT9A 3I50E 1URZA 5LCVA 4GT0A 1UZGA 4UTCA 3P54A 3UC0A 1RERA 4UTAA 5LBSA 3N42F 4UTBA 1OKEA 5IREA 2HG0A 5GZNA 3J2PA 2I69A 3J27A 5H37A 3N44F
chains in the Genus database with same CATH superfamily
4GSXA 1OK8A 1OANA 3N40F 2ALAA 4FG0A 3N41F 3UAJA 3G7TA 5IZ7A 1SVBA 5LBVA 5JHLA 4UT6A 3C6EA 5GZOA 3N43F 4ADJA 5JHMA 4HJ1A 1TG8A 3C5XA 4UT9A 3I50E 1URZA 5LCVA 4GT0A 4ADGA 4B3VA 1UZGA 4UTCA 3P54A 3UC0A 1RERA 4UTAA 5LBSA 3U2GA 3N42F 4UTBA 4ADIA 1OKEA 5IREA 2HG0A 4OJCA 3U2HA 5GZNA 3J2PA 2I69A 3J27A 4OJDH 4OJEH 1WLGA 5H37A 3N44F
chains in the Genus database with same CATH topology
4GSXA 1OK8A 1OANA 3N40F 2ALAA 4FG0A 3N41F 3UAJA 3G7TA 5IZ7A 1SVBA 5LBVA 5JHLA 4UT6A 3C6EA 5GZOA 3N43F 5JHMA 1TG8A 3C5XA 4UT9A 3I50E 1URZA 5LCVA 4GT0A 1UZGA 4UTCA 3P54A 3UC0A 1RERA 4UTAA 5LBSA 3N42F 4UTBA 1OKEA 5IREA 2HG0A 5GZNA 3J2PA 2I69A 3J27A 5H37A 3N44F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GSX A;  1OK8 A;  1OAN A;  3N40 F;  2ALA A;  4FG0 A;  3N41 F;  3UAJ A;  3G7T A;  5IZ7 A;  1SVB A;  5LBV A;  5JHL A;  4UT6 A;  3C6E A;  5GZO A;  3N43 F;  5JHM A;  1TG8 A;  3C5X A;  4UT9 A;  3I50 E;  1URZ A;  5LCV A;  4GT0 A;  1UZG A;  4UTC A;  3P54 A;  3UC0 A;  1RER A;  4UTA A;  5LBS A;  3N42 F;  4UTB A;  1OKE A;  5IRE A;  2HG0 A;  5GZN A;  3J2P A;  2I69 A;  3J27 A;  5H37 A;  3N44 F; 
#chains in the Genus database with same CATH topology
 4GSX A;  1OK8 A;  1OAN A;  3N40 F;  2ALA A;  4FG0 A;  3N41 F;  3UAJ A;  3G7T A;  5IZ7 A;  1SVB A;  5LBV A;  5JHL A;  4UT6 A;  3C6E A;  5GZO A;  3N43 F;  4ADJ A;  5JHM A;  4HJ1 A;  1TG8 A;  3C5X A;  4UT9 A;  3I50 E;  1URZ A;  5LCV A;  4GT0 A;  4ADG A;  4B3V A;  1UZG A;  4UTC A;  3P54 A;  3UC0 A;  1RER A;  4UTA A;  5LBS A;  3U2G A;  3N42 F;  4UTB A;  4ADI A;  1OKE A;  5IRE A;  2HG0 A;  4OJC A;  3U2H A;  5GZN A;  3J2P A;  2I69 A;  3J27 A;  4OJD H;  4OJE H;  1WLG A;  5H37 A;  3N44 F; 
#chains in the Genus database with same CATH homology
 4GSX A;  1OK8 A;  1OAN A;  3N40 F;  2ALA A;  4FG0 A;  3N41 F;  3UAJ A;  3G7T A;  5IZ7 A;  1SVB A;  5LBV A;  5JHL A;  4UT6 A;  3C6E A;  5GZO A;  3N43 F;  5JHM A;  1TG8 A;  3C5X A;  4UT9 A;  3I50 E;  1URZ A;  5LCV A;  4GT0 A;  1UZG A;  4UTC A;  3P54 A;  3UC0 A;  1RER A;  4UTA A;  5LBS A;  3N42 F;  4UTB A;  1OKE A;  5IRE A;  2HG0 A;  5GZN A;  3J2P A;  2I69 A;  3J27 A;  5H37 A;  3N44 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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