3I50E

Crystal structure of the west nile virus envelope glycoprotein in complex with the e53 antibody fab
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
291
structure length
273
Chain Sequence
SNRDFLEGVSGATWVDLVLEGDSCVTIMSKDKPTIDVKMMNMEAANLAEVRSYCYLATVSDLSTKAACPTMGEAHNDKRADPAFVCRQGVVDRGWGNGCGLFGKGSIDTCAKFACSTKAIGRTILKENIKYEVAIFVHQAGRFSITPAAPSYTLKLGEYGEVTVDCEPRSGIDTNAYYVMTVGTKTFLVHREWFMDLNLPWSSAGSTVWRNRETLMEFEEPHATKQSVIALGSQEGALHQALAGAIPVEFSSNTVKLTSGHLKCRVKMEKLQL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.
pubmed doi rcsb
molecule keywords Envelope glycoprotein
molecule tags Viral protein/immune system
source organism West nile virus
total genus 40
structure length 273
sequence length 291
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2009-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00869 Flavi_glycoprot Flavivirus glycoprotein, central and dimerisation domains
E PF02832 Flavi_glycop_C Flavivirus glycoprotein, immunoglobulin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.98.10 Mainly Beta Sandwich Tick-borne Encephalitis virus Glycoprotein; domain 1 Tick-borne Encephalitis virus Glycoprotein, domain 1 3i50E00
3G7TA 5IZ7A 5GZOA 4UTBA 3N40F 4UTAA 4UTCA 3N41F 1URZA 5IREA 1TG8A 4GSXA 3UC0A 3C6EA 3UAJA 1OANA 1UZGA 3J2PA 5LBSA 5H37A 1RERA 3J27A 3N44F 4GT0A 2ALAA 3N43F 4FG0A 1OK8A 3P54A 3I50E 5GZNA 5JHLA 5LCVA 4UT9A 3N42F 1SVBA 2HG0A 2I69A 5JHMA 1OKEA 4UT6A 5LBVA 3C5XA
chains in the Genus database with same CATH superfamily
3G7TA 5IZ7A 4B3VA 5GZOA 4UTBA 3N40F 4UTAA 3U2HA 4UTCA 3N41F 1URZA 5IREA 1TG8A 4OJCA 4GSXA 3UC0A 3C6EA 3UAJA 1WLGA 1OANA 4ADIA 1UZGA 3J2PA 5LBSA 5H37A 1RERA 3J27A 3N44F 4OJDH 4GT0A 2ALAA 3N43F 4FG0A 4ADGA 1OK8A 3P54A 3I50E 3U2GA 4ADJA 4HJ1A 5GZNA 5JHLA 4OJEH 4UT9A 5LCVA 3N42F 1SVBA 2HG0A 2I69A 5JHMA 1OKEA 4UT6A 5LBVA 3C5XA
chains in the Genus database with same CATH topology
3G7TA 5IZ7A 5GZOA 4UTBA 3N40F 4UTAA 4UTCA 3N41F 1URZA 5IREA 1TG8A 4GSXA 3UC0A 3C6EA 3UAJA 1OANA 1UZGA 3J2PA 5LBSA 5H37A 1RERA 3J27A 3N44F 4GT0A 2ALAA 3N43F 4FG0A 1OK8A 3P54A 3I50E 5GZNA 5JHLA 5LCVA 4UT9A 3N42F 1SVBA 2HG0A 2I69A 5JHMA 1OKEA 4UT6A 5LBVA 3C5XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G7T A;  5IZ7 A;  5GZO A;  4UTB A;  3N40 F;  4UTA A;  4UTC A;  3N41 F;  1URZ A;  5IRE A;  1TG8 A;  4GSX A;  3UC0 A;  3C6E A;  3UAJ A;  1OAN A;  1UZG A;  3J2P A;  5LBS A;  5H37 A;  1RER A;  3J27 A;  3N44 F;  4GT0 A;  2ALA A;  3N43 F;  4FG0 A;  1OK8 A;  3P54 A;  3I50 E;  5GZN A;  5JHL A;  5LCV A;  4UT9 A;  3N42 F;  1SVB A;  2HG0 A;  2I69 A;  5JHM A;  1OKE A;  4UT6 A;  5LBV A;  3C5X A; 
#chains in the Genus database with same CATH topology
 3G7T A;  5IZ7 A;  4B3V A;  5GZO A;  4UTB A;  3N40 F;  4UTA A;  3U2H A;  4UTC A;  3N41 F;  1URZ A;  5IRE A;  1TG8 A;  4OJC A;  4GSX A;  3UC0 A;  3C6E A;  3UAJ A;  1WLG A;  1OAN A;  4ADI A;  1UZG A;  3J2P A;  5LBS A;  5H37 A;  1RER A;  3J27 A;  3N44 F;  4OJD H;  4GT0 A;  2ALA A;  3N43 F;  4FG0 A;  4ADG A;  1OK8 A;  3P54 A;  3I50 E;  3U2G A;  4ADJ A;  4HJ1 A;  5GZN A;  5JHL A;  4OJE H;  4UT9 A;  5LCV A;  3N42 F;  1SVB A;  2HG0 A;  2I69 A;  5JHM A;  1OKE A;  4UT6 A;  5LBV A;  3C5X A; 
#chains in the Genus database with same CATH homology
 3G7T A;  5IZ7 A;  5GZO A;  4UTB A;  3N40 F;  4UTA A;  4UTC A;  3N41 F;  1URZ A;  5IRE A;  1TG8 A;  4GSX A;  3UC0 A;  3C6E A;  3UAJ A;  1OAN A;  1UZG A;  3J2P A;  5LBS A;  5H37 A;  1RER A;  3J27 A;  3N44 F;  4GT0 A;  2ALA A;  3N43 F;  4FG0 A;  1OK8 A;  3P54 A;  3I50 E;  5GZN A;  5JHL A;  5LCV A;  4UT9 A;  3N42 F;  1SVB A;  2HG0 A;  2I69 A;  5JHM A;  1OKE A;  4UT6 A;  5LBV A;  3C5X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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