3UC0A

Crystal structure of domain i of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5h2
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
125
structure length
111
Chain Sequence
MRCVGVGNRDFVEGVSGGAWVDLVLEHGGCVTTMAQGKPTLDFELTKTTAGGLEYTVVVTVHGVTAMITPRSPSVEVKLPDYGELTLDCEPRSGTGHLKCKVRMEKLRIKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus.
pubmed doi rcsb
molecule keywords envelope protein
molecule tags Viral protein/immune system
source organism Dengue virus 4
total genus 16
structure length 111
sequence length 125
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00869 Flavi_glycoprot Flavivirus glycoprotein, central and dimerisation domains
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.98.10 Mainly Beta Sandwich Tick-borne Encephalitis virus Glycoprotein; domain 1 Tick-borne Encephalitis virus Glycoprotein, domain 1 3uc0A00
4UTBA 3I50E 5IZ7A 5GZNA 3N44F 3N42F 4UTAA 1OKEA 1OK8A 1OANA 3J27A 2HG0A 3N43F 5LBVA 1UZGA 2ALAA 3C5XA 3P54A 1URZA 4UT9A 5LBSA 3N41F 2I69A 3G7TA 3C6EA 3UAJA 1SVBA 5GZOA 4FG0A 5IREA 4GT0A 4GSXA 3UC0A 3N40F 3J2PA 5H37A 4UTCA 1RERA 4UT6A 5JHMA 5JHLA 5LCVA 1TG8A
chains in the Genus database with same CATH superfamily
4UTBA 3I50E 5IZ7A 5GZNA 3N44F 3N42F 4UTAA 1OKEA 1OK8A 1OANA 3J27A 2HG0A 3N43F 5LBVA 4OJEH 4ADJA 1UZGA 2ALAA 3C5XA 3P54A 1URZA 4UT9A 5LBSA 3U2GA 3N41F 2I69A 4ADGA 3G7TA 3C6EA 4OJCA 3UAJA 1SVBA 4ADIA 4B3VA 5GZOA 4FG0A 4HJ1A 5IREA 4GT0A 4GSXA 1WLGA 3UC0A 3N40F 3J2PA 5H37A 4UTCA 1RERA 4UT6A 5JHMA 5JHLA 5LCVA 4OJDH 1TG8A 3U2HA
chains in the Genus database with same CATH topology
4UTBA 3I50E 5IZ7A 5GZNA 3N44F 3N42F 4UTAA 1OKEA 1OK8A 1OANA 3J27A 2HG0A 3N43F 5LBVA 1UZGA 2ALAA 3C5XA 3P54A 1URZA 4UT9A 5LBSA 3N41F 2I69A 3G7TA 3C6EA 3UAJA 1SVBA 5GZOA 4FG0A 5IREA 4GT0A 4GSXA 3UC0A 3N40F 3J2PA 5H37A 4UTCA 1RERA 4UT6A 5JHMA 5JHLA 5LCVA 1TG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UTB A;  3I50 E;  5IZ7 A;  5GZN A;  3N44 F;  3N42 F;  4UTA A;  1OKE A;  1OK8 A;  1OAN A;  3J27 A;  2HG0 A;  3N43 F;  5LBV A;  1UZG A;  2ALA A;  3C5X A;  3P54 A;  1URZ A;  4UT9 A;  5LBS A;  3N41 F;  2I69 A;  3G7T A;  3C6E A;  3UAJ A;  1SVB A;  5GZO A;  4FG0 A;  5IRE A;  4GT0 A;  4GSX A;  3UC0 A;  3N40 F;  3J2P A;  5H37 A;  4UTC A;  1RER A;  4UT6 A;  5JHM A;  5JHL A;  5LCV A;  1TG8 A; 
#chains in the Genus database with same CATH topology
 4UTB A;  3I50 E;  5IZ7 A;  5GZN A;  3N44 F;  3N42 F;  4UTA A;  1OKE A;  1OK8 A;  1OAN A;  3J27 A;  2HG0 A;  3N43 F;  5LBV A;  4OJE H;  4ADJ A;  1UZG A;  2ALA A;  3C5X A;  3P54 A;  1URZ A;  4UT9 A;  5LBS A;  3U2G A;  3N41 F;  2I69 A;  4ADG A;  3G7T A;  3C6E A;  4OJC A;  3UAJ A;  1SVB A;  4ADI A;  4B3V A;  5GZO A;  4FG0 A;  4HJ1 A;  5IRE A;  4GT0 A;  4GSX A;  1WLG A;  3UC0 A;  3N40 F;  3J2P A;  5H37 A;  4UTC A;  1RER A;  4UT6 A;  5JHM A;  5JHL A;  5LCV A;  4OJD H;  1TG8 A;  3U2H A; 
#chains in the Genus database with same CATH homology
 4UTB A;  3I50 E;  5IZ7 A;  5GZN A;  3N44 F;  3N42 F;  4UTA A;  1OKE A;  1OK8 A;  1OAN A;  3J27 A;  2HG0 A;  3N43 F;  5LBV A;  1UZG A;  2ALA A;  3C5X A;  3P54 A;  1URZ A;  4UT9 A;  5LBS A;  3N41 F;  2I69 A;  3G7T A;  3C6E A;  3UAJ A;  1SVB A;  5GZO A;  4FG0 A;  5IRE A;  4GT0 A;  4GSX A;  3UC0 A;  3N40 F;  3J2P A;  5H37 A;  4UTC A;  1RER A;  4UT6 A;  5JHM A;  5JHL A;  5LCV A;  1TG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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