3UC0A

Crystal structure of domain i of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5h2
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
125
structure length
111
Chain Sequence
MRCVGVGNRDFVEGVSGGAWVDLVLEHGGCVTTMAQGKPTLDFELTKTTAGGLEYTVVVTVHGVTAMITPRSPSVEVKLPDYGELTLDCEPRSGTGHLKCKVRMEKLRIKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus.
pubmed doi rcsb
molecule keywords envelope protein
molecule tags Viral protein/immune system
source organism Dengue virus 4
total genus 16
structure length 111
sequence length 125
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00869 Flavi_glycoprot Flavivirus glycoprotein, central and dimerisation domains
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.98.10 Mainly Beta Sandwich Tick-borne Encephalitis virus Glycoprotein; domain 1 Tick-borne Encephalitis virus Glycoprotein, domain 1 3uc0A00
4UT9A 1UZGA 1OK8A 2HG0A 4GSXA 4UT6A 5LBVA 3N41F 4UTBA 1RERA 3J27A 1OKEA 4FG0A 3C6EA 3N40F 1OANA 5GZOA 3UC0A 2I69A 5JHLA 5GZNA 3I50E 4GT0A 3N43F 5H37A 5JHMA 1SVBA 1URZA 1TG8A 5IREA 3UAJA 3G7TA 3J2PA 3N44F 3N42F 4UTCA 4UTAA 3C5XA 3P54A 5LCVA 2ALAA 5IZ7A 5LBSA
chains in the Genus database with same CATH superfamily
4UT9A 1UZGA 1OK8A 2HG0A 4GSXA 4UT6A 5LBVA 3N41F 4ADJA 4UTBA 1RERA 3J27A 1OKEA 4OJEH 4FG0A 3C6EA 3N40F 1OANA 4OJCA 5GZOA 3UC0A 2I69A 5JHLA 3U2GA 4B3VA 4ADIA 5GZNA 3I50E 4GT0A 3N43F 4OJDH 5H37A 4ADGA 1SVBA 1URZA 1TG8A 5JHMA 1WLGA 3G7TA 3UAJA 5IREA 3J2PA 3N44F 3N42F 4UTCA 4UTAA 3C5XA 3U2HA 3P54A 5LCVA 4HJ1A 2ALAA 5IZ7A 5LBSA
chains in the Genus database with same CATH topology
4UT9A 1UZGA 1OK8A 2HG0A 4GSXA 4UT6A 5LBVA 3N41F 4UTBA 1RERA 3J27A 1OKEA 4FG0A 3C6EA 3N40F 1OANA 5GZOA 3UC0A 2I69A 5JHLA 5GZNA 3I50E 4GT0A 3N43F 5H37A 5JHMA 1SVBA 1URZA 1TG8A 5IREA 3UAJA 3G7TA 3J2PA 3N44F 3N42F 4UTCA 4UTAA 3C5XA 3P54A 5LCVA 2ALAA 5IZ7A 5LBSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UT9 A;  1UZG A;  1OK8 A;  2HG0 A;  4GSX A;  4UT6 A;  5LBV A;  3N41 F;  4UTB A;  1RER A;  3J27 A;  1OKE A;  4FG0 A;  3C6E A;  3N40 F;  1OAN A;  5GZO A;  3UC0 A;  2I69 A;  5JHL A;  5GZN A;  3I50 E;  4GT0 A;  3N43 F;  5H37 A;  5JHM A;  1SVB A;  1URZ A;  1TG8 A;  5IRE A;  3UAJ A;  3G7T A;  3J2P A;  3N44 F;  3N42 F;  4UTC A;  4UTA A;  3C5X A;  3P54 A;  5LCV A;  2ALA A;  5IZ7 A;  5LBS A; 
#chains in the Genus database with same CATH topology
 4UT9 A;  1UZG A;  1OK8 A;  2HG0 A;  4GSX A;  4UT6 A;  5LBV A;  3N41 F;  4ADJ A;  4UTB A;  1RER A;  3J27 A;  1OKE A;  4OJE H;  4FG0 A;  3C6E A;  3N40 F;  1OAN A;  4OJC A;  5GZO A;  3UC0 A;  2I69 A;  5JHL A;  3U2G A;  4B3V A;  4ADI A;  5GZN A;  3I50 E;  4GT0 A;  3N43 F;  4OJD H;  5H37 A;  4ADG A;  1SVB A;  1URZ A;  1TG8 A;  5JHM A;  1WLG A;  3G7T A;  3UAJ A;  5IRE A;  3J2P A;  3N44 F;  3N42 F;  4UTC A;  4UTA A;  3C5X A;  3U2H A;  3P54 A;  5LCV A;  4HJ1 A;  2ALA A;  5IZ7 A;  5LBS A; 
#chains in the Genus database with same CATH homology
 4UT9 A;  1UZG A;  1OK8 A;  2HG0 A;  4GSX A;  4UT6 A;  5LBV A;  3N41 F;  4UTB A;  1RER A;  3J27 A;  1OKE A;  4FG0 A;  3C6E A;  3N40 F;  1OAN A;  5GZO A;  3UC0 A;  2I69 A;  5JHL A;  5GZN A;  3I50 E;  4GT0 A;  3N43 F;  5H37 A;  5JHM A;  1SVB A;  1URZ A;  1TG8 A;  5IRE A;  3UAJ A;  3G7T A;  3J2P A;  3N44 F;  3N42 F;  4UTC A;  4UTA A;  3C5X A;  3P54 A;  5LCV A;  2ALA A;  5IZ7 A;  5LBS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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