3UXUA

The structure of the catalytic domain of the sulfolobus spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of dna cleavage in trans
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
159
structure length
159
Chain Sequence
IYIPTLEEIKRTLQLAKDYSENVYFIYRIALESGVRLSEVLKVLKEPERDICGNDVCYYPLSWTRGYKGVFYVFHITPLKRVEVTKWAIADFERRHKDAIAIKYFRKFVASKMAELSVPLDIIDFIQGRKPARVLTQHYVSLFGIAKEQYKKYAEWLKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structure of an Archaeal Viral Integrase Reveals an Evolutionarily Conserved Catalytic Core yet Supports a Mechanism of DNA Cleavage in trans.
pubmed doi rcsb
molecule keywords Probable integrase
molecule tags Recombination
source organism Sulfolobus virus 1
total genus 56
structure length 159
sequence length 159
ec nomenclature
pdb deposition date 2011-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16795 Phage_integr_3 Archaeal phage integrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.443.10 Mainly Alpha Orthogonal Bundle hpI Integrase; Chain A Intergrase catalytic core 3uxuA00
1FLOA 1Z19A 2HOFA 4A8EA 1Q3UA 1KBUA 3VCFA 3C28A 1AE9A 1MA7A 1M6XA 1Q3VA 2A3VA 1NZBA 5C6KA 1A0PA 1PVQA 4CRXA 1M6XC 3UXUA 2CRXA 5CRXA 5DORA 5DCFA 1AIHA 1Z1BA 1P4EA 1DRGA 1F44A 1XNSA 3MGVA 3C29A 1PVPA 1P7DA 1CRXA 1P4EC 1XO0A 3NKHA 1OUQA 3CRXA 1PVRA 2HOIA 4DKSA
chains in the Genus database with same CATH superfamily
1FLOA 1Z19A 2HOFA 4A8EA 1Q3UA 1KBUA 3VCFA 3C28A 4E0GA 1AE9A 4E0PA 1MA7A 1M6XA 4E0ZA 1Q3VA 4F41A 3T79A 1NZBA 2A3VA 5C6KA 2V6EA 4F43A 1A0PA 1PVQA 4CRXA 1M6XC 3UXUA 2CRXA 5CRXA 5DORA 5DCFA 1AIHA 1Z1BA 1P4EA 1DRGA 1F44A 4E0YA 1XNSA 3MGVA 3C29A 1PVPA 1P7DA 1CRXA 4E10A 1P4EC 1XO0A 3SQIA 4E0JA 4DWPA 3NKHA 1OUQA 3CRXA 4ACOA 1PVRA 2HOIA 4DKSA
chains in the Genus database with same CATH topology
1FLOA 1Z19A 2HOFA 4A8EA 1Q3UA 1KBUA 3VCFA 3C28A 1AE9A 1MA7A 1M6XA 1Q3VA 2A3VA 1NZBA 5C6KA 1A0PA 1PVQA 4CRXA 1M6XC 3UXUA 2CRXA 5CRXA 5DORA 5DCFA 1AIHA 1Z1BA 1P4EA 1DRGA 1F44A 1XNSA 3MGVA 3C29A 1PVPA 1P7DA 1CRXA 1P4EC 1XO0A 3NKHA 1OUQA 3CRXA 1PVRA 2HOIA 4DKSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FLO A;  1Z19 A;  2HOF A;  4A8E A;  1Q3U A;  1KBU A;  3VCF A;  3C28 A;  1AE9 A;  1MA7 A;  1M6X A;  1Q3V A;  2A3V A;  1NZB A;  5C6K A;  1A0P A;  1PVQ A;  4CRX A;  1M6X C;  3UXU A;  2CRX A;  5CRX A;  5DOR A;  5DCF A;  1AIH A;  1Z1B A;  1P4E A;  1DRG A;  1F44 A;  1XNS A;  3MGV A;  3C29 A;  1PVP A;  1P7D A;  1CRX A;  1P4E C;  1XO0 A;  3NKH A;  1OUQ A;  3CRX A;  1PVR A;  2HOI A;  4DKS A; 
#chains in the Genus database with same CATH topology
 1FLO A;  1Z19 A;  2HOF A;  4A8E A;  1Q3U A;  1KBU A;  3VCF A;  3C28 A;  4E0G A;  1AE9 A;  4E0P A;  1MA7 A;  1M6X A;  4E0Z A;  1Q3V A;  4F41 A;  3T79 A;  1NZB A;  2A3V A;  5C6K A;  2V6E A;  4F43 A;  1A0P A;  1PVQ A;  4CRX A;  1M6X C;  3UXU A;  2CRX A;  5CRX A;  5DOR A;  5DCF A;  1AIH A;  1Z1B A;  1P4E A;  1DRG A;  1F44 A;  4E0Y A;  1XNS A;  3MGV A;  3C29 A;  1PVP A;  1P7D A;  1CRX A;  4E10 A;  1P4E C;  1XO0 A;  3SQI A;  4E0J A;  4DWP A;  3NKH A;  1OUQ A;  3CRX A;  4ACO A;  1PVR A;  2HOI A;  4DKS A; 
#chains in the Genus database with same CATH homology
 1FLO A;  1Z19 A;  2HOF A;  4A8E A;  1Q3U A;  1KBU A;  3VCF A;  3C28 A;  1AE9 A;  1MA7 A;  1M6X A;  1Q3V A;  2A3V A;  1NZB A;  5C6K A;  1A0P A;  1PVQ A;  4CRX A;  1M6X C;  3UXU A;  2CRX A;  5CRX A;  5DOR A;  5DCF A;  1AIH A;  1Z1B A;  1P4E A;  1DRG A;  1F44 A;  1XNS A;  3MGV A;  3C29 A;  1PVP A;  1P7D A;  1CRX A;  1P4E C;  1XO0 A;  3NKH A;  1OUQ A;  3CRX A;  1PVR A;  2HOI A;  4DKS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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