3ZFNA

Crystal structure of product-like, processed n-terminal protease npro
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
148
structure length
148
Chain Sequence
MEPLYDKNGAVLFGEPSDTHPQSTLKLPHPRGEKEVIVGIRDLPRKGDCRTGNRLGPVSGLFVKPGPVFYQDYSGPVYHRAPLEQFKQAPMCEVTKRIGRVTGSDGNLYHMYVCTDGCILVKTAKREGQDVLKWVYNVLDSPIWVTSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis
pubmed doi rcsb
molecule keywords N-TERMINAL PROTEASE NPRO
molecule tags Hydrolase
source organism Pestivirus strain d32/00_hobi
total genus 32
structure length 148
sequence length 148
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.140.40 Mainly Beta Roll Spermidine Synthase; Chain: A, domain 2 Spermidine Synthase; Chain: A, domain 2 3zfnA02
4H9KA 3ZFUA 3ZFQA 3ZFOA 3ZFNA 3ZFTA 3ZFPA 4H9JA 3ZFRA
chains in the Genus database with same CATH superfamily
3B7PA 4H9KA 2CMGA 2O0LA 2O06A 4YUZA 3ZFOA 2CMHA 3ZFPA 2I7CA 2PSSA 2PT9A 1IY9A 4YUVA 1TVFA 2PT6A 3ANXA 2PWPA 4YUYA 3C6KA 3ZFQA 1MJFA 1INLA 2HTEA 2B2CA 3BWCA 4YUXA 4CXMA 3C6MA 3MFDA 2E5WA 1UIRA 2ZSUA 3BWBA 3ZFUA 4BP1A 3ZFNA 2O07A 2O05A 4BP3A 3ZFRA 4UOEA 5B1SA 4YV2A 1JQ3A 4CWAA 4F98A 4YV1A 4YV0A 1XJ5A 4YUWA 3HUMA 2Q41A 3O4FA 3RW9A 3HUNA 4H9JA 3ZFTA 3RIEA
chains in the Genus database with same CATH topology
4F98A 4H9KA 3ZFUA 3ZFQA 3ZFOA 3ZFNA 3ZFPA 3ZFTA 4H9JA 3MFDA 3ZFRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H9K A;  3ZFU A;  3ZFQ A;  3ZFO A;  3ZFN A;  3ZFT A;  3ZFP A;  4H9J A;  3ZFR A; 
#chains in the Genus database with same CATH topology
 3B7P A;  4H9K A;  2CMG A;  2O0L A;  2O06 A;  4YUZ A;  3ZFO A;  2CMH A;  3ZFP A;  2I7C A;  2PSS A;  2PT9 A;  1IY9 A;  4YUV A;  1TVF A;  2PT6 A;  3ANX A;  2PWP A;  4YUY A;  3C6K A;  3ZFQ A;  1MJF A;  1INL A;  2HTE A;  2B2C A;  3BWC A;  4YUX A;  4CXM A;  3C6M A;  3MFD A;  2E5W A;  1UIR A;  2ZSU A;  3BWB A;  3ZFU A;  4BP1 A;  3ZFN A;  2O07 A;  2O05 A;  4BP3 A;  3ZFR A;  4UOE A;  5B1S A;  4YV2 A;  1JQ3 A;  4CWA A;  4F98 A;  4YV1 A;  4YV0 A;  1XJ5 A;  4YUW A;  3HUM A;  2Q41 A;  3O4F A;  3RW9 A;  3HUN A;  4H9J A;  3ZFT A;  3RIE A; 
#chains in the Genus database with same CATH homology
 4F98 A;  4H9K A;  3ZFU A;  3ZFQ A;  3ZFO A;  3ZFN A;  3ZFP A;  3ZFT A;  4H9J A;  3MFD A;  3ZFR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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