3ZFQA

Crystal structure of product-like, processed n-terminal protease npro with mercury
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
148
structure length
148
Chain Sequence
MEPLYDKNGAVLFGEPSDTHPQSTLKLPHPRGEKEVIVGIRDLPRKGDCRTGNRLGPVSGLFVKPGPVFYQDYSGPVYHRAPLEQFKQAPMCEVTKRIGRVTGSDGNLYHMYVCTDGCILVKTAKREGQDVLKWVYNVLDSPIWVTSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords N-TERMINAL PROTEASE NPRO
publication title Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis
pubmed doi rcsb
source organism Pestivirus strain d32/00_hobi
total genus 32
structure length 148
sequence length 148
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.140.40 Mainly Beta Roll Spermidine Synthase; Chain: A, domain 2 Spermidine Synthase; Chain: A, domain 2 3zfqA02
3ZFQA 4H9KA 3ZFPA 3ZFUA 3ZFNA 4H9JA 3ZFTA 3ZFOA 3ZFRA
chains in the Genus database with same CATH superfamily
2Q41A 3B7PA 3ZFQA 4H9KA 2O07A 2B2CA 3ZFUA 3HUNA 3ZFNA 3ZFOA 2O06A 1JQ3A 3MFDA 4BP1A 1IY9A 2HTEA 4YV2A 4YUZA 4CWAA 1XJ5A 3ZFPA 1INLA 3O4FA 2PSSA 4YUWA 3C6MA 3RW9A 3ZFRA 4YV0A 2CMGA 1UIRA 2PT6A 3C6KA 3ZFTA 4F98A 2O05A 3RIEA 1TVFA 5B1SA 2I7CA 1MJFA 3HUMA 4CXMA 2O0LA 2PWPA 3ANXA 4YUVA 4YV1A 4YUXA 3BWBA 4H9JA 2CMHA 4UOEA 4BP3A 2PT9A 2ZSUA 3BWCA 4YUYA 2E5WA
chains in the Genus database with same CATH topology
3ZFQA 4H9KA 3ZFPA 3ZFUA 3ZFNA 4H9JA 3ZFTA 3ZFOA 4F98A 3ZFRA 3MFDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZFQ A;  4H9K A;  3ZFP A;  3ZFU A;  3ZFN A;  4H9J A;  3ZFT A;  3ZFO A;  3ZFR A; 
#chains in the Genus database with same CATH topology
 2Q41 A;  3B7P A;  3ZFQ A;  4H9K A;  2O07 A;  2B2C A;  3ZFU A;  3HUN A;  3ZFN A;  3ZFO A;  2O06 A;  1JQ3 A;  3MFD A;  4BP1 A;  1IY9 A;  2HTE A;  4YV2 A;  4YUZ A;  4CWA A;  1XJ5 A;  3ZFP A;  1INL A;  3O4F A;  2PSS A;  4YUW A;  3C6M A;  3RW9 A;  3ZFR A;  4YV0 A;  2CMG A;  1UIR A;  2PT6 A;  3C6K A;  3ZFT A;  4F98 A;  2O05 A;  3RIE A;  1TVF A;  5B1S A;  2I7C A;  1MJF A;  3HUM A;  4CXM A;  2O0L A;  2PWP A;  3ANX A;  4YUV A;  4YV1 A;  4YUX A;  3BWB A;  4H9J A;  2CMH A;  4UOE A;  4BP3 A;  2PT9 A;  2ZSU A;  3BWC A;  4YUY A;  2E5W A; 
#chains in the Genus database with same CATH homology
 3ZFQ A;  4H9K A;  3ZFP A;  3ZFU A;  3ZFN A;  4H9J A;  3ZFT A;  3ZFO A;  4F98 A;  3ZFR A;  3MFD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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