3ZFQA

Crystal structure of product-like, processed n-terminal protease npro with mercury
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
148
structure length
148
Chain Sequence
MEPLYDKNGAVLFGEPSDTHPQSTLKLPHPRGEKEVIVGIRDLPRKGDCRTGNRLGPVSGLFVKPGPVFYQDYSGPVYHRAPLEQFKQAPMCEVTKRIGRVTGSDGNLYHMYVCTDGCILVKTAKREGQDVLKWVYNVLDSPIWVTSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis
pubmed doi rcsb
molecule keywords N-TERMINAL PROTEASE NPRO
molecule tags Hydrolase
source organism Pestivirus strain d32/00_hobi
total genus 32
structure length 148
sequence length 148
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.140.40 Mainly Beta Roll Spermidine Synthase; Chain: A, domain 2 Spermidine Synthase; Chain: A, domain 2 3zfqA02
3ZFTA 3ZFOA 3ZFUA 4H9JA 4H9KA 3ZFNA 3ZFRA 3ZFPA 3ZFQA
chains in the Genus database with same CATH superfamily
3O4FA 1TVFA 3ZFTA 3ZFOA 2PWPA 2HTEA 3BWBA 4H9JA 3ZFUA 2CMHA 3ANXA 4YUVA 1UIRA 4UOEA 4CWAA 3HUNA 3BWCA 4BP3A 4YV2A 3MFDA 3RIEA 3RW9A 4YV1A 4YUZA 2CMGA 1INLA 4YUYA 2PT9A 2PSSA 4CXMA 1IY9A 3HUMA 2ZSUA 2E5WA 4F98A 3ZFQA 2O05A 4YUWA 1JQ3A 4H9KA 1XJ5A 2O0LA 2B2CA 1MJFA 3ZFNA 3C6MA 5B1SA 3ZFRA 4BP1A 4YV0A 3B7PA 4YUXA 2Q41A 2O07A 2PT6A 2O06A 3ZFPA 3C6KA 2I7CA
chains in the Genus database with same CATH topology
3ZFTA 3ZFOA 3ZFUA 4H9JA 4H9KA 3ZFNA 3ZFRA 3ZFPA 4F98A 3ZFQA 3MFDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZFT A;  3ZFO A;  3ZFU A;  4H9J A;  4H9K A;  3ZFN A;  3ZFR A;  3ZFP A;  3ZFQ A; 
#chains in the Genus database with same CATH topology
 3O4F A;  1TVF A;  3ZFT A;  3ZFO A;  2PWP A;  2HTE A;  3BWB A;  4H9J A;  3ZFU A;  2CMH A;  3ANX A;  4YUV A;  1UIR A;  4UOE A;  4CWA A;  3HUN A;  3BWC A;  4BP3 A;  4YV2 A;  3MFD A;  3RIE A;  3RW9 A;  4YV1 A;  4YUZ A;  2CMG A;  1INL A;  4YUY A;  2PT9 A;  2PSS A;  4CXM A;  1IY9 A;  3HUM A;  2ZSU A;  2E5W A;  4F98 A;  3ZFQ A;  2O05 A;  4YUW A;  1JQ3 A;  4H9K A;  1XJ5 A;  2O0L A;  2B2C A;  1MJF A;  3ZFN A;  3C6M A;  5B1S A;  3ZFR A;  4BP1 A;  4YV0 A;  3B7P A;  4YUX A;  2Q41 A;  2O07 A;  2PT6 A;  2O06 A;  3ZFP A;  3C6K A;  2I7C A; 
#chains in the Genus database with same CATH homology
 3ZFT A;  3ZFO A;  3ZFU A;  4H9J A;  4H9K A;  3ZFN A;  3ZFR A;  3ZFP A;  4F98 A;  3ZFQ A;  3MFD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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