4AP2B

Crystal structure of the human klhl11-cul3 complex at 2.8a resolution
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
365
structure length
359
Chain Sequence
RIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEPVDYRQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords KELCH-LIKE PROTEIN 11
total genus 145
structure length 359
sequence length 365
ec nomenclature
pdb deposition date 2012-03-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4ap2B01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4ap2B02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4ap2B03
3DPLC 4A64A 4JGHD 4F52A 1LDKA 3RTRA 1LDJA 4HXIB 4AP2B 2WZKA 4EOZB 1U6GA 4WQOD 3DQVC 4P5OA 4APFB 1LDKB 4N9F3
chains in the Genus database with same CATH superfamily
2B1EA 3CMLA 4F52A 3RRCA 3RTRA 4HXIB 4APFB 3DPLC 4YFSA 4NUUA 1LDJA 3BQIA 4AP2B 3DQVC 4JGHD 3BQKA 3BQLA 1LDKA 3CPZA 2Y8DA 1U6GA 1LDKB 2XU0A 4N9F3 4WQOD 4NUVA 4A64A 2PFVA 4EOZB 5F3JA 4P5OA 2WAUA 2WZKA
chains in the Genus database with same CATH topology
3DPLC 4A64A 4JGHD 4F52A 1LDKA 3RTRA 1LDJA 4HXIB 4AP2B 2WZKA 4EOZB 1U6GA 4WQOD 3DQVC 4P5OA 4APFB 1LDKB 4N9F3
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DPL C;  4A64 A;  4JGH D;  4F52 A;  1LDK A;  3RTR A;  1LDJ A;  4HXI B;  4AP2 B;  2WZK A;  4EOZ B;  1U6G A;  4WQO D;  3DQV C;  4P5O A;  4APF B;  1LDK B;  4N9F 3; 
#chains in the Genus database with same CATH topology
 2B1E A;  3CML A;  4F52 A;  3RRC A;  3RTR A;  4HXI B;  4APF B;  3DPL C;  4YFS A;  4NUU A;  1LDJ A;  3BQI A;  4AP2 B;  3DQV C;  4JGH D;  3BQK A;  3BQL A;  1LDK A;  3CPZ A;  2Y8D A;  1U6G A;  1LDK B;  2XU0 A;  4N9F 3;  4WQO D;  4NUV A;  4A64 A;  2PFV A;  4EOZ B;  5F3J A;  4P5O A;  2WAU A;  2WZK A; 
#chains in the Genus database with same CATH homology
 3DPL C;  4A64 A;  4JGH D;  4F52 A;  1LDK A;  3RTR A;  1LDJ A;  4HXI B;  4AP2 B;  2WZK A;  4EOZ B;  1U6G A;  4WQO D;  3DQV C;  4P5O A;  4APF B;  1LDK B;  4N9F 3; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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