4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule keywords KELCH-LIKE PROTEIN 11
molecule tags Cell cycle
source organism Homo sapiens
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
4WQOD 4A64A 3RTRA 1U6GA 1LDKB 4EOZB 4AP2B 1LDJA 2WZKA 3DPLC 4P5OA 4F52A 4N9F3 4JGHD 4HXIB 3DQVC 1LDKA 4APFB
chains in the Genus database with same CATH superfamily
3CPZA 1LDJA 2XU0A 4N9F3 4HXIB 3RRCA 3DQVC 3RTRA 4APFB 4WQOD 4A64A 1U6GA 3BQIA 4AP2B 2PFVA 4NUVA 4P5OA 2B1EA 3CMLA 5F3JA 3BQKA 4F52A 4JGHD 2Y8DA 4YFSA 1LDKA 1LDKB 4EOZB 2WAUA 2WZKA 3DPLC 3BQLA 4NUUA
chains in the Genus database with same CATH topology
4WQOD 4A64A 3RTRA 1U6GA 1LDKB 4EOZB 4AP2B 1LDJA 2WZKA 3DPLC 4P5OA 4F52A 4N9F3 4JGHD 4HXIB 3DQVC 1LDKA 4APFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WQO D;  4A64 A;  3RTR A;  1U6G A;  1LDK B;  4EOZ B;  4AP2 B;  1LDJ A;  2WZK A;  3DPL C;  4P5O A;  4F52 A;  4N9F 3;  4JGH D;  4HXI B;  3DQV C;  1LDK A;  4APF B; 
#chains in the Genus database with same CATH topology
 3CPZ A;  1LDJ A;  2XU0 A;  4N9F 3;  4HXI B;  3RRC A;  3DQV C;  3RTR A;  4APF B;  4WQO D;  4A64 A;  1U6G A;  3BQI A;  4AP2 B;  2PFV A;  4NUV A;  4P5O A;  2B1E A;  3CML A;  5F3J A;  3BQK A;  4F52 A;  4JGH D;  2Y8D A;  4YFS A;  1LDK A;  1LDK B;  4EOZ B;  2WAU A;  2WZK A;  3DPL C;  3BQL A;  4NUU A; 
#chains in the Genus database with same CATH homology
 4WQO D;  4A64 A;  3RTR A;  1U6G A;  1LDK B;  4EOZ B;  4AP2 B;  1LDJ A;  2WZK A;  3DPL C;  4P5O A;  4F52 A;  4N9F 3;  4JGH D;  4HXI B;  3DQV C;  1LDK A;  4APF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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