4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords KELCH-LIKE PROTEIN 11
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
3DQVC 2WZKA 4JGHD 1U6GA 3DPLC 4A64A 4EOZB 3RTRA 4P5OA 1LDKB 4N9F3 4WQOD 1LDJA 4APFB 1LDKA 4AP2B 4HXIB 4F52A
chains in the Genus database with same CATH superfamily
3DPLC 2WAUA 4NUVA 1LDKA 3RRCA 4YFSA 2B1EA 4JGHD 3CPZA 3RTRA 1LDKB 4WQOD 4APFB 4AP2B 3BQLA 2WZKA 4NUUA 1U6GA 4EOZB 3BQIA 4P5OA 4N9F3 5F3JA 2Y8DA 2PFVA 4F52A 3CMLA 3DQVC 4A64A 2XU0A 3BQKA 1LDJA 4HXIB
chains in the Genus database with same CATH topology
3DQVC 2WZKA 4JGHD 1U6GA 3DPLC 4A64A 4EOZB 3RTRA 4P5OA 1LDKB 4N9F3 4WQOD 1LDJA 4APFB 1LDKA 4AP2B 4HXIB 4F52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DQV C;  2WZK A;  4JGH D;  1U6G A;  3DPL C;  4A64 A;  4EOZ B;  3RTR A;  4P5O A;  1LDK B;  4N9F 3;  4WQO D;  1LDJ A;  4APF B;  1LDK A;  4AP2 B;  4HXI B;  4F52 A; 
#chains in the Genus database with same CATH topology
 3DPL C;  2WAU A;  4NUV A;  1LDK A;  3RRC A;  4YFS A;  2B1E A;  4JGH D;  3CPZ A;  3RTR A;  1LDK B;  4WQO D;  4APF B;  4AP2 B;  3BQL A;  2WZK A;  4NUU A;  1U6G A;  4EOZ B;  3BQI A;  4P5O A;  4N9F 3;  5F3J A;  2Y8D A;  2PFV A;  4F52 A;  3CML A;  3DQV C;  4A64 A;  2XU0 A;  3BQK A;  1LDJ A;  4HXI B; 
#chains in the Genus database with same CATH homology
 3DQV C;  2WZK A;  4JGH D;  1U6G A;  3DPL C;  4A64 A;  4EOZ B;  3RTR A;  4P5O A;  1LDK B;  4N9F 3;  4WQO D;  1LDJ A;  4APF B;  1LDK A;  4AP2 B;  4HXI B;  4F52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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