4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
source organism Homo sapiens
publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule keywords KELCH-LIKE PROTEIN 11
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
4EOZB 4WQOD 4APFB 1LDJA 3RTRA 2WZKA 3DQVC 3DPLC 4HXIB 1U6GA 4AP2B 1LDKA 4F52A 1LDKB 4N9F3 4JGHD 4P5OA 4A64A
chains in the Genus database with same CATH superfamily
4NUVA 4APFB 3BQLA 3BQIA 2B1EA 2Y8DA 4P5OA 4A64A 3CMLA 4HXIB 1U6GA 1LDKA 3RRCA 4N9F3 4YFSA 4EOZB 3BQKA 1LDJA 3RTRA 2WZKA 3DPLC 1LDKB 3CPZA 4JGHD 4WQOD 2WAUA 3DQVC 5F3JA 4NUUA 2XU0A 4F52A 4AP2B 2PFVA
chains in the Genus database with same CATH topology
4EOZB 4WQOD 4APFB 1LDJA 3RTRA 2WZKA 3DQVC 3DPLC 4HXIB 1U6GA 4AP2B 1LDKA 4F52A 1LDKB 4N9F3 4JGHD 4P5OA 4A64A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EOZ B;  4WQO D;  4APF B;  1LDJ A;  3RTR A;  2WZK A;  3DQV C;  3DPL C;  4HXI B;  1U6G A;  4AP2 B;  1LDK A;  4F52 A;  1LDK B;  4N9F 3;  4JGH D;  4P5O A;  4A64 A; 
#chains in the Genus database with same CATH topology
 4NUV A;  4APF B;  3BQL A;  3BQI A;  2B1E A;  2Y8D A;  4P5O A;  4A64 A;  3CML A;  4HXI B;  1U6G A;  1LDK A;  3RRC A;  4N9F 3;  4YFS A;  4EOZ B;  3BQK A;  1LDJ A;  3RTR A;  2WZK A;  3DPL C;  1LDK B;  3CPZ A;  4JGH D;  4WQO D;  2WAU A;  3DQV C;  5F3J A;  4NUU A;  2XU0 A;  4F52 A;  4AP2 B;  2PFV A; 
#chains in the Genus database with same CATH homology
 4EOZ B;  4WQO D;  4APF B;  1LDJ A;  3RTR A;  2WZK A;  3DQV C;  3DPL C;  4HXI B;  1U6G A;  4AP2 B;  1LDK A;  4F52 A;  1LDK B;  4N9F 3;  4JGH D;  4P5O A;  4A64 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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