4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule keywords KELCH-LIKE PROTEIN 11
molecule tags Cell cycle
source organism Homo sapiens
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
4AP2B 3DPLC 1LDJA 4P5OA 4WQOD 4A64A 4EOZB 1U6GA 4JGHD 4APFB 3DQVC 4N9F3 3RTRA 1LDKA 4F52A 4HXIB 1LDKB 2WZKA
chains in the Genus database with same CATH superfamily
2WAUA 3BQLA 3BQKA 3CPZA 3BQIA 4NUVA 4EOZB 4N9F3 4NUUA 3DPLC 2PFVA 4WQOD 3RRCA 3CMLA 1LDKA 4JGHD 4AP2B 4P5OA 2Y8DA 5F3JA 1LDJA 4A64A 2B1EA 1U6GA 4YFSA 4APFB 3DQVC 3RTRA 4F52A 4HXIB 2XU0A 1LDKB 2WZKA
chains in the Genus database with same CATH topology
4AP2B 3DPLC 1LDJA 4P5OA 4WQOD 4A64A 4EOZB 1U6GA 4JGHD 4APFB 3DQVC 4N9F3 3RTRA 1LDKA 4F52A 4HXIB 1LDKB 2WZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AP2 B;  3DPL C;  1LDJ A;  4P5O A;  4WQO D;  4A64 A;  4EOZ B;  1U6G A;  4JGH D;  4APF B;  3DQV C;  4N9F 3;  3RTR A;  1LDK A;  4F52 A;  4HXI B;  1LDK B;  2WZK A; 
#chains in the Genus database with same CATH topology
 2WAU A;  3BQL A;  3BQK A;  3CPZ A;  3BQI A;  4NUV A;  4EOZ B;  4N9F 3;  4NUU A;  3DPL C;  2PFV A;  4WQO D;  3RRC A;  3CML A;  1LDK A;  4JGH D;  4AP2 B;  4P5O A;  2Y8D A;  5F3J A;  1LDJ A;  4A64 A;  2B1E A;  1U6G A;  4YFS A;  4APF B;  3DQV C;  3RTR A;  4F52 A;  4HXI B;  2XU0 A;  1LDK B;  2WZK A; 
#chains in the Genus database with same CATH homology
 4AP2 B;  3DPL C;  1LDJ A;  4P5O A;  4WQO D;  4A64 A;  4EOZ B;  1U6G A;  4JGH D;  4APF B;  3DQV C;  4N9F 3;  3RTR A;  1LDK A;  4F52 A;  4HXI B;  1LDK B;  2WZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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