4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule keywords KELCH-LIKE PROTEIN 11
molecule tags Cell cycle
source organism Homo sapiens
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
1U6GA 1LDKA 4JGHD 4WQOD 1LDKB 4A64A 4AP2B 4HXIB 1LDJA 4APFB 3DPLC 4EOZB 4N9F3 2WZKA 3RTRA 3DQVC 4F52A 4P5OA
chains in the Genus database with same CATH superfamily
1LDKB 4HXIB 4APFB 3RRCA 3BQKA 4NUUA 3CMLA 4N9F3 3DQVC 2B1EA 4F52A 2Y8DA 4A64A 5F3JA 4YFSA 3DPLC 3RTRA 3CPZA 1U6GA 3BQIA 4JGHD 2WAUA 2PFVA 4EOZB 2WZKA 4NUVA 4P5OA 1LDKA 4WQOD 4AP2B 1LDJA 3BQLA 2XU0A
chains in the Genus database with same CATH topology
1U6GA 1LDKA 4JGHD 4WQOD 1LDKB 4A64A 4AP2B 4HXIB 1LDJA 4APFB 3DPLC 4EOZB 4N9F3 2WZKA 3RTRA 3DQVC 4F52A 4P5OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U6G A;  1LDK A;  4JGH D;  4WQO D;  1LDK B;  4A64 A;  4AP2 B;  4HXI B;  1LDJ A;  4APF B;  3DPL C;  4EOZ B;  4N9F 3;  2WZK A;  3RTR A;  3DQV C;  4F52 A;  4P5O A; 
#chains in the Genus database with same CATH topology
 1LDK B;  4HXI B;  4APF B;  3RRC A;  3BQK A;  4NUU A;  3CML A;  4N9F 3;  3DQV C;  2B1E A;  4F52 A;  2Y8D A;  4A64 A;  5F3J A;  4YFS A;  3DPL C;  3RTR A;  3CPZ A;  1U6G A;  3BQI A;  4JGH D;  2WAU A;  2PFV A;  4EOZ B;  2WZK A;  4NUV A;  4P5O A;  1LDK A;  4WQO D;  4AP2 B;  1LDJ A;  3BQL A;  2XU0 A; 
#chains in the Genus database with same CATH homology
 1U6G A;  1LDK A;  4JGH D;  4WQO D;  1LDK B;  4A64 A;  4AP2 B;  4HXI B;  1LDJ A;  4APF B;  3DPL C;  4EOZ B;  4N9F 3;  2WZK A;  3RTR A;  3DQV C;  4F52 A;  4P5O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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