4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords KELCH-LIKE PROTEIN 11
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
3DPLC 4N9F3 4F52A 4APFB 3RTRA 4P5OA 1LDJA 2WZKA 4JGHD 4A64A 4AP2B 3DQVC 4EOZB 4WQOD 1U6GA 1LDKB 4HXIB 1LDKA
chains in the Genus database with same CATH superfamily
4AP2B 2Y8DA 2B1EA 4EOZB 2PFVA 4NUVA 1LDKB 3DPLC 4N9F3 5F3JA 4A64A 2WZKA 4YFSA 4WQOD 1U6GA 4NUUA 2WAUA 4F52A 4APFB 3RTRA 3CMLA 4JGHD 3RRCA 3DQVC 3BQKA 4HXIB 1LDKA 2XU0A 4P5OA 1LDJA 3CPZA 3BQIA 3BQLA
chains in the Genus database with same CATH topology
3DPLC 4N9F3 4F52A 4APFB 3RTRA 4P5OA 1LDJA 2WZKA 4JGHD 4A64A 4AP2B 3DQVC 4EOZB 4WQOD 1U6GA 1LDKB 4HXIB 1LDKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DPL C;  4N9F 3;  4F52 A;  4APF B;  3RTR A;  4P5O A;  1LDJ A;  2WZK A;  4JGH D;  4A64 A;  4AP2 B;  3DQV C;  4EOZ B;  4WQO D;  1U6G A;  1LDK B;  4HXI B;  1LDK A; 
#chains in the Genus database with same CATH topology
 4AP2 B;  2Y8D A;  2B1E A;  4EOZ B;  2PFV A;  4NUV A;  1LDK B;  3DPL C;  4N9F 3;  5F3J A;  4A64 A;  2WZK A;  4YFS A;  4WQO D;  1U6G A;  4NUU A;  2WAU A;  4F52 A;  4APF B;  3RTR A;  3CML A;  4JGH D;  3RRC A;  3DQV C;  3BQK A;  4HXI B;  1LDK A;  2XU0 A;  4P5O A;  1LDJ A;  3CPZ A;  3BQI A;  3BQL A; 
#chains in the Genus database with same CATH homology
 3DPL C;  4N9F 3;  4F52 A;  4APF B;  3RTR A;  4P5O A;  1LDJ A;  2WZK A;  4JGH D;  4A64 A;  4AP2 B;  3DQV C;  4EOZ B;  4WQO D;  1U6G A;  1LDK B;  4HXI B;  1LDK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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