4D0O | Genus

Total Genus 98

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	98
sequence length	237
structure length	234
Chain Sequence	ENLYFQSMEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 234 atoms

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234 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Cell cycle
source organism	Homo sapiens
publication title	The Crystal Structure of the Rhoa : Akap-Lbc Dh-Ph Domain Complex. pubmed doi rcsb
molecule keywords	A-KINASE ANCHOR PROTEIN 13
total genus	98
structure length	234
sequence length	237
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-04-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	4d0oA00

1TXDA 1DBHA 5FI1A 3QBVB 3KZ1A 4D0NB 1KZ7A 1KZGA 1LB1A 3ODOA 1NTYA 3T06A 4GZUA 4YONA 5FI0A 1XD4A 3GF9A 2NZ8B 3EO2A 1F5XA 2PZ1A 1KI1B 3ODWA 4MT7A 1X86A 2DX1A 2VRWB 3JV3A 3ODXA 2KR9A 3MPXA 4D0OA 2Z0QA 1XCGA 3KSYA 3P6AA 3KY9A 2RGNB 4GYVA 5JHHA 4GOUA 1RJ2A 1BY1A 1FOEA 3BJIA 2DFKA 5JHGA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1TXD A;  1DBH A;  5FI1 A;  3QBV B;  3KZ1 A;  4D0N B;  1KZ7 A;  1KZG A;  1LB1 A;  3ODO A;  1NTY A;  3T06 A;  4GZU A;  4YON A;  5FI0 A;  1XD4 A;  3GF9 A;  2NZ8 B;  3EO2 A;  1F5X A;  2PZ1 A;  1KI1 B;  3ODW A;  4MT7 A;  1X86 A;  2DX1 A;  2VRW B;  3JV3 A;  3ODX A;  2KR9 A;  3MPX A;  4D0O A;  2Z0Q A;  1XCG A;  3KSY A;  3P6A A;  3KY9 A;  2RGN B;  4GYV A;  5JHH A;  4GOU A;  1RJ2 A;  1BY1 A;  1FOE A;  3BJI A;  2DFK A;  5JHG A; 
#chains in the Genus database with same CATH topology
 1TXD A;  1DBH A;  5FI1 A;  3QBV B;  3KZ1 A;  4D0N B;  1KZ7 A;  1KZG A;  1LB1 A;  3ODO A;  1NTY A;  3T06 A;  4GZU A;  4YON A;  5FI0 A;  1XD4 A;  3GF9 A;  2NZ8 B;  3EO2 A;  1F5X A;  2PZ1 A;  1KI1 B;  3ODW A;  4MT7 A;  1X86 A;  2DX1 A;  2VRW B;  3JV3 A;  3ODX A;  2KR9 A;  3MPX A;  4D0O A;  2Z0Q A;  1XCG A;  3KSY A;  3P6A A;  3KY9 A;  2RGN B;  4GYV A;  5JHH A;  4GOU A;  1RJ2 A;  1BY1 A;  1FOE A;  3BJI A;  2DFK A;  5JHG A; 
#chains in the Genus database with same CATH homology
 1TXD A;  1DBH A;  5FI1 A;  3QBV B;  3KZ1 A;  4D0N B;  1KZ7 A;  1KZG A;  1LB1 A;  3ODO A;  1NTY A;  3T06 A;  4GZU A;  4YON A;  5FI0 A;  1XD4 A;  3GF9 A;  2NZ8 B;  3EO2 A;  1F5X A;  2PZ1 A;  1KI1 B;  3ODW A;  4MT7 A;  1X86 A;  2DX1 A;  2VRW B;  3JV3 A;  3ODX A;  2KR9 A;  3MPX A;  4D0O A;  2Z0Q A;  1XCG A;  3KSY A;  3P6A A;  3KY9 A;  2RGN B;  4GYV A;  5JHH A;  4GOU A;  1RJ2 A;  1BY1 A;  1FOE A;  3BJI A;  2DFK A;  5JHG A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4D0OA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations