4D0OA

Akap13 (akap-lbc) dh domain
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
237
structure length
234
Chain Sequence
ENLYFQSMEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Crystal Structure of the Rhoa : Akap-Lbc Dh-Ph Domain Complex.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords A-KINASE ANCHOR PROTEIN 13
total genus 98
structure length 234
sequence length 237
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 4d0oA00
4GZUA 3KZ1A 2VRWB 1KI1B 3ODXA 4D0NB 1BY1A 2DX1A 5JHHA 3ODWA 1X86A 1KZ7A 1KZGA 1XD4A 1RJ2A 1XCGA 3EO2A 4D0OA 4GOUA 1DBHA 1FOEA 3T06A 2Z0QA 1TXDA 2KR9A 2PZ1A 3GF9A 3ODOA 3KY9A 2RGNB 1NTYA 5FI0A 1LB1A 5FI1A 5JHGA 3JV3A 3QBVB 4GYVA 4YONA 2NZ8B 4MT7A 1F5XA 2DFKA 3KSYA 3P6AA 3MPXA 3BJIA
chains in the Genus database with same CATH superfamily
4GZUA 3KZ1A 2VRWB 1KI1B 3ODXA 4D0NB 1BY1A 2DX1A 5JHHA 3ODWA 1X86A 1KZ7A 1KZGA 1XD4A 1RJ2A 1XCGA 3EO2A 4D0OA 4GOUA 1DBHA 1FOEA 3T06A 2Z0QA 1TXDA 2KR9A 2PZ1A 3GF9A 3ODOA 3KY9A 2RGNB 1NTYA 5FI0A 1LB1A 5FI1A 5JHGA 3JV3A 3QBVB 4GYVA 4YONA 2NZ8B 4MT7A 1F5XA 2DFKA 3KSYA 3P6AA 3MPXA 3BJIA
chains in the Genus database with same CATH topology
4GZUA 3KZ1A 2VRWB 1KI1B 3ODXA 4D0NB 1BY1A 2DX1A 5JHHA 3ODWA 1X86A 1KZ7A 1KZGA 1XD4A 1RJ2A 1XCGA 3EO2A 4D0OA 4GOUA 1DBHA 1FOEA 3T06A 2Z0QA 1TXDA 2KR9A 2PZ1A 3GF9A 3ODOA 3KY9A 2RGNB 1NTYA 5FI0A 1LB1A 5FI1A 5JHGA 3JV3A 3QBVB 4GYVA 4YONA 2NZ8B 4MT7A 1F5XA 2DFKA 3KSYA 3P6AA 3MPXA 3BJIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GZU A;  3KZ1 A;  2VRW B;  1KI1 B;  3ODX A;  4D0N B;  1BY1 A;  2DX1 A;  5JHH A;  3ODW A;  1X86 A;  1KZ7 A;  1KZG A;  1XD4 A;  1RJ2 A;  1XCG A;  3EO2 A;  4D0O A;  4GOU A;  1DBH A;  1FOE A;  3T06 A;  2Z0Q A;  1TXD A;  2KR9 A;  2PZ1 A;  3GF9 A;  3ODO A;  3KY9 A;  2RGN B;  1NTY A;  5FI0 A;  1LB1 A;  5FI1 A;  5JHG A;  3JV3 A;  3QBV B;  4GYV A;  4YON A;  2NZ8 B;  4MT7 A;  1F5X A;  2DFK A;  3KSY A;  3P6A A;  3MPX A;  3BJI A; 
#chains in the Genus database with same CATH topology
 4GZU A;  3KZ1 A;  2VRW B;  1KI1 B;  3ODX A;  4D0N B;  1BY1 A;  2DX1 A;  5JHH A;  3ODW A;  1X86 A;  1KZ7 A;  1KZG A;  1XD4 A;  1RJ2 A;  1XCG A;  3EO2 A;  4D0O A;  4GOU A;  1DBH A;  1FOE A;  3T06 A;  2Z0Q A;  1TXD A;  2KR9 A;  2PZ1 A;  3GF9 A;  3ODO A;  3KY9 A;  2RGN B;  1NTY A;  5FI0 A;  1LB1 A;  5FI1 A;  5JHG A;  3JV3 A;  3QBV B;  4GYV A;  4YON A;  2NZ8 B;  4MT7 A;  1F5X A;  2DFK A;  3KSY A;  3P6A A;  3MPX A;  3BJI A; 
#chains in the Genus database with same CATH homology
 4GZU A;  3KZ1 A;  2VRW B;  1KI1 B;  3ODX A;  4D0N B;  1BY1 A;  2DX1 A;  5JHH A;  3ODW A;  1X86 A;  1KZ7 A;  1KZG A;  1XD4 A;  1RJ2 A;  1XCG A;  3EO2 A;  4D0O A;  4GOU A;  1DBH A;  1FOE A;  3T06 A;  2Z0Q A;  1TXD A;  2KR9 A;  2PZ1 A;  3GF9 A;  3ODO A;  3KY9 A;  2RGN B;  1NTY A;  5FI0 A;  1LB1 A;  5FI1 A;  5JHG A;  3JV3 A;  3QBV B;  4GYV A;  4YON A;  2NZ8 B;  4MT7 A;  1F5X A;  2DFK A;  3KSY A;  3P6A A;  3MPX A;  3BJI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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