4DRAE

Crystal structure of mhf complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the FANCM-MHF complex reveals physical features for functional assembly
pubmed doi rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 24
structure length 74
sequence length 74
chains with identical sequence F, G, H
ec nomenclature
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4draE02
4E45B 4E44B 4DRBJ 3B0BC 4DRAE 4NE6B 4NE3B 4NE5B
chains in the Genus database with same CATH superfamily
2LO0A 4QPMA 1GTPA 1WURA 2WSCK 1AIPC 4DU6A 2LNZA 2WSFK 4NE5B 4Q7JA 3LW5K 1FB1A 1EFUB 4E45B 1WM9A 4E44B 4JA3A 4DRBJ 4NE3B 1A8RA 1WPLA 1TFEA 1N3SA 2O01G 1N3RA 1A9CA 1IS8A 1N3TA 1WUQA 2KR1A 2WSEG 3B0BC 4DRAE 4NE6B 1EL6A 2WSCG 1IS7A 2PN0A 2WSFG 3LW5G 1FBXA 4R8QA 5DMZA 3VEJA 2P11A 3BMBA 2WSEK
chains in the Genus database with same CATH topology
2LO0A 4QPMA 1GTPA 1WURA 1AIPC 4DU6A 2LNZA 4NE5B 4Q7JA 4E45B 1FB1A 1EFUB 1WM9A 4E44B 4JA3A 4DRBJ 4NE3B 1A8RA 1WPLA 1TFEA 1N3SA 1N3RA 1A9CA 1IS8A 1N3TA 1WUQA 2KR1A 3B0BC 4DRAE 4NE6B 1EL6A 1IS7A 2PN0A 4R8QA 1FBXA 5DMZA 3VEJA 2P11A 3BMBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E45 B;  4E44 B;  4DRB J;  3B0B C;  4DRA E;  4NE6 B;  4NE3 B;  4NE5 B; 
#chains in the Genus database with same CATH topology
 2LO0 A;  4QPM A;  1GTP A;  1WUR A;  2WSC K;  1AIP C;  4DU6 A;  2LNZ A;  2WSF K;  4NE5 B;  4Q7J A;  3LW5 K;  1FB1 A;  1EFU B;  4E45 B;  1WM9 A;  4E44 B;  4JA3 A;  4DRB J;  4NE3 B;  1A8R A;  1WPL A;  1TFE A;  1N3S A;  2O01 G;  1N3R A;  1A9C A;  1IS8 A;  1N3T A;  1WUQ A;  2KR1 A;  2WSE G;  3B0B C;  4DRA E;  4NE6 B;  1EL6 A;  2WSC G;  1IS7 A;  2PN0 A;  2WSF G;  3LW5 G;  1FBX A;  4R8Q A;  5DMZ A;  3VEJ A;  2P11 A;  3BMB A;  2WSE K; 
#chains in the Genus database with same CATH homology
 2LO0 A;  4QPM A;  1GTP A;  1WUR A;  1AIP C;  4DU6 A;  2LNZ A;  4NE5 B;  4Q7J A;  4E45 B;  1FB1 A;  1EFU B;  1WM9 A;  4E44 B;  4JA3 A;  4DRB J;  4NE3 B;  1A8R A;  1WPL A;  1TFE A;  1N3S A;  1N3R A;  1A9C A;  1IS8 A;  1N3T A;  1WUQ A;  2KR1 A;  3B0B C;  4DRA E;  4NE6 B;  1EL6 A;  1IS7 A;  2PN0 A;  4R8Q A;  1FBX A;  5DMZ A;  3VEJ A;  2P11 A;  3BMB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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