4DRAE

Crystal structure of mhf complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the FANCM-MHF complex reveals physical features for functional assembly
pubmed doi rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 24
structure length 74
sequence length 74
chains with identical sequence F, G, H
ec nomenclature
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4draE02
4DRBJ 4E45B 4DRAE 4NE6B 4E44B 3B0BC 4NE5B 4NE3B
chains in the Genus database with same CATH superfamily
4JA3A 4E45B 2WSFK 1AIPC 2LNZA 1FB1A 4Q7JA 1EL6A 1GTPA 2WSCK 4R8QA 5DMZA 2KR1A 3LW5G 1N3SA 1A8RA 1WURA 2WSFG 1N3TA 4QPMA 3BMBA 2WSCG 1IS7A 1N3RA 3B0BC 4DRBJ 2O01G 1IS8A 2PN0A 2WSEK 4DU6A 4E44B 1FBXA 3VEJA 1WUQA 1WPLA 2P11A 4DRAE 1TFEA 1A9CA 4NE6B 3LW5K 1EFUB 1WM9A 2WSEG 4NE5B 4NE3B 2LO0A
chains in the Genus database with same CATH topology
4JA3A 4E45B 1AIPC 2LNZA 1FB1A 4Q7JA 1EL6A 1GTPA 4R8QA 5DMZA 2KR1A 1N3SA 1A8RA 1WURA 1N3TA 4QPMA 3BMBA 1IS7A 1N3RA 4DRBJ 1IS8A 2PN0A 4E44B 4DU6A 1FBXA 3VEJA 1WUQA 1WPLA 2P11A 4DRAE 1TFEA 1A9CA 4NE6B 1EFUB 1WM9A 3B0BC 4NE5B 4NE3B 2LO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRB J;  4E45 B;  4DRA E;  4NE6 B;  4E44 B;  3B0B C;  4NE5 B;  4NE3 B; 
#chains in the Genus database with same CATH topology
 4JA3 A;  4E45 B;  2WSF K;  1AIP C;  2LNZ A;  1FB1 A;  4Q7J A;  1EL6 A;  1GTP A;  2WSC K;  4R8Q A;  5DMZ A;  2KR1 A;  3LW5 G;  1N3S A;  1A8R A;  1WUR A;  2WSF G;  1N3T A;  4QPM A;  3BMB A;  2WSC G;  1IS7 A;  1N3R A;  3B0B C;  4DRB J;  2O01 G;  1IS8 A;  2PN0 A;  2WSE K;  4DU6 A;  4E44 B;  1FBX A;  3VEJ A;  1WUQ A;  1WPL A;  2P11 A;  4DRA E;  1TFE A;  1A9C A;  4NE6 B;  3LW5 K;  1EFU B;  1WM9 A;  2WSE G;  4NE5 B;  4NE3 B;  2LO0 A; 
#chains in the Genus database with same CATH homology
 4JA3 A;  4E45 B;  1AIP C;  2LNZ A;  1FB1 A;  4Q7J A;  1EL6 A;  1GTP A;  4R8Q A;  5DMZ A;  2KR1 A;  1N3S A;  1A8R A;  1WUR A;  1N3T A;  4QPM A;  3BMB A;  1IS7 A;  1N3R A;  4DRB J;  1IS8 A;  2PN0 A;  4E44 B;  4DU6 A;  1FBX A;  3VEJ A;  1WUQ A;  1WPL A;  2P11 A;  4DRA E;  1TFE A;  1A9C A;  4NE6 B;  1EFU B;  1WM9 A;  3B0B C;  4NE5 B;  4NE3 B;  2LO0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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