4DRAE

Crystal structure of mhf complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
source organism Homo sapiens
publication title The structure of the FANCM-MHF complex reveals physical features for functional assembly
pubmed doi rcsb
molecule keywords Centromere protein S
total genus 24
structure length 74
sequence length 74
chains with identical sequence F, G, H
ec nomenclature
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4draE02
4NE6B 4E44B 4NE5B 4E45B 4DRBJ 4DRAE 4NE3B 3B0BC
chains in the Genus database with same CATH superfamily
1WUQA 4E44B 4QPMA 3BMBA 4NE5B 5DMZA 2KR1A 2LNZA 1AIPC 2WSEG 1A9CA 4JA3A 1WM9A 2P11A 3LW5G 4R8QA 1IS7A 2PN0A 2LO0A 2WSCG 2WSFG 1N3RA 4DRBJ 1N3TA 4NE6B 1WPLA 1IS8A 2WSEK 4Q7JA 1FB1A 1EFUB 3LW5K 4DRAE 1EL6A 1A8RA 1TFEA 3B0BC 1N3SA 2WSCK 2WSFK 4DU6A 4E45B 2O01G 3VEJA 1GTPA 4NE3B 1FBXA 1WURA
chains in the Genus database with same CATH topology
1WUQA 4E44B 4QPMA 3BMBA 4NE5B 5DMZA 2KR1A 2LNZA 1AIPC 1A9CA 4JA3A 1WM9A 2P11A 4R8QA 1IS7A 2PN0A 2LO0A 1N3RA 4DRBJ 1N3TA 4NE6B 1WPLA 1IS8A 4Q7JA 1FB1A 1EFUB 4DRAE 1EL6A 1A8RA 1TFEA 3B0BC 1N3SA 4DU6A 4E45B 3VEJA 1GTPA 4NE3B 1FBXA 1WURA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE6 B;  4E44 B;  4NE5 B;  4E45 B;  4DRB J;  4DRA E;  4NE3 B;  3B0B C; 
#chains in the Genus database with same CATH topology
 1WUQ A;  4E44 B;  4QPM A;  3BMB A;  4NE5 B;  5DMZ A;  2KR1 A;  2LNZ A;  1AIP C;  2WSE G;  1A9C A;  4JA3 A;  1WM9 A;  2P11 A;  3LW5 G;  4R8Q A;  1IS7 A;  2PN0 A;  2LO0 A;  2WSC G;  2WSF G;  1N3R A;  4DRB J;  1N3T A;  4NE6 B;  1WPL A;  1IS8 A;  2WSE K;  4Q7J A;  1FB1 A;  1EFU B;  3LW5 K;  4DRA E;  1EL6 A;  1A8R A;  1TFE A;  3B0B C;  1N3S A;  2WSC K;  2WSF K;  4DU6 A;  4E45 B;  2O01 G;  3VEJ A;  1GTP A;  4NE3 B;  1FBX A;  1WUR A; 
#chains in the Genus database with same CATH homology
 1WUQ A;  4E44 B;  4QPM A;  3BMB A;  4NE5 B;  5DMZ A;  2KR1 A;  2LNZ A;  1AIP C;  1A9C A;  4JA3 A;  1WM9 A;  2P11 A;  4R8Q A;  1IS7 A;  2PN0 A;  2LO0 A;  1N3R A;  4DRB J;  1N3T A;  4NE6 B;  1WPL A;  1IS8 A;  4Q7J A;  1FB1 A;  1EFU B;  4DRA E;  1EL6 A;  1A8R A;  1TFE A;  3B0B C;  1N3S A;  4DU6 A;  4E45 B;  3VEJ A;  1GTP A;  4NE3 B;  1FBX A;  1WUR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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