4DRAE

Crystal structure of mhf complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the FANCM-MHF complex reveals physical features for functional assembly
pubmed doi rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Centromere protein S
total genus 24
structure length 74
sequence length 74
chains with identical sequence F, G, H
ec nomenclature
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4draE02
3B0BC 4DRBJ 4E44B 4DRAE 4NE6B 4NE3B 4E45B 4NE5B
chains in the Genus database with same CATH superfamily
3VEJA 1EL6A 1EFUB 2WSCK 2WSCG 2WSFK 4E44B 2WSFG 4R8QA 5DMZA 1IS7A 1WUQA 3BMBA 4NE6B 3B0BC 1IS8A 1N3TA 1N3RA 1N3SA 2PN0A 4JA3A 2KR1A 4DRAE 2P11A 4NE5B 1WM9A 4DU6A 1TFEA 2WSEK 4Q7JA 1A8RA 4NE3B 4E45B 2O01G 4QPMA 1A9CA 1WURA 4DRBJ 1FB1A 3LW5K 2LNZA 2LO0A 3LW5G 1WPLA 1GTPA 2WSEG 1AIPC 1FBXA
chains in the Genus database with same CATH topology
3VEJA 1EL6A 1EFUB 4E44B 4R8QA 5DMZA 1IS7A 1WUQA 3BMBA 4NE6B 3B0BC 1IS8A 1N3TA 1N3RA 1N3SA 2PN0A 4JA3A 2KR1A 4DRAE 2P11A 4NE5B 1WM9A 4DU6A 1TFEA 4Q7JA 1A8RA 4NE3B 4E45B 4QPMA 1A9CA 1WURA 4DRBJ 1FB1A 2LNZA 2LO0A 1WPLA 1GTPA 1AIPC 1FBXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B0B C;  4DRB J;  4E44 B;  4DRA E;  4NE6 B;  4NE3 B;  4E45 B;  4NE5 B; 
#chains in the Genus database with same CATH topology
 3VEJ A;  1EL6 A;  1EFU B;  2WSC K;  2WSC G;  2WSF K;  4E44 B;  2WSF G;  4R8Q A;  5DMZ A;  1IS7 A;  1WUQ A;  3BMB A;  4NE6 B;  3B0B C;  1IS8 A;  1N3T A;  1N3R A;  1N3S A;  2PN0 A;  4JA3 A;  2KR1 A;  4DRA E;  2P11 A;  4NE5 B;  1WM9 A;  4DU6 A;  1TFE A;  2WSE K;  4Q7J A;  1A8R A;  4NE3 B;  4E45 B;  2O01 G;  4QPM A;  1A9C A;  1WUR A;  4DRB J;  1FB1 A;  3LW5 K;  2LNZ A;  2LO0 A;  3LW5 G;  1WPL A;  1GTP A;  2WSE G;  1AIP C;  1FBX A; 
#chains in the Genus database with same CATH homology
 3VEJ A;  1EL6 A;  1EFU B;  4E44 B;  4R8Q A;  5DMZ A;  1IS7 A;  1WUQ A;  3BMB A;  4NE6 B;  3B0B C;  1IS8 A;  1N3T A;  1N3R A;  1N3S A;  2PN0 A;  4JA3 A;  2KR1 A;  4DRA E;  2P11 A;  4NE5 B;  1WM9 A;  4DU6 A;  1TFE A;  4Q7J A;  1A8R A;  4NE3 B;  4E45 B;  4QPM A;  1A9C A;  1WUR A;  4DRB J;  1FB1 A;  2LNZ A;  2LO0 A;  1WPL A;  1GTP A;  1AIP C;  1FBX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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