4NE6B

Human mhf1-mhf2 complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
molecule keywords Centromere protein S
publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
source organism Homo sapiens
total genus 23
structure length 74
sequence length 74
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne6B02
4E45B 4NE6B 3B0BC 4E44B 4DRBJ 4DRAE 4NE5B 4NE3B
chains in the Genus database with same CATH superfamily
3VEJA 1EL6A 5DMZA 2LNZA 4DRBJ 1AIPC 2WSFG 2P11A 2O01G 2WSEG 1N3RA 1A9CA 4JA3A 4E45B 4NE6B 3B0BC 2KR1A 1WUQA 1IS7A 1N3SA 2PN0A 1N3TA 4DRAE 4E44B 1WM9A 1A8RA 3LW5K 4NE5B 1TFEA 1FBXA 2WSCK 3BMBA 1GTPA 1WURA 3LW5G 2LO0A 4QPMA 2WSCG 1EFUB 4DU6A 1WPLA 4Q7JA 1IS8A 2WSEK 1FB1A 4R8QA 2WSFK 4NE3B
chains in the Genus database with same CATH topology
3VEJA 1EL6A 5DMZA 2LNZA 4DRBJ 1AIPC 2P11A 1N3RA 1A9CA 4JA3A 4E45B 4NE6B 3B0BC 2KR1A 1WUQA 1IS7A 1N3SA 2PN0A 1N3TA 4DRAE 4E44B 1WM9A 1A8RA 4NE5B 1TFEA 1FBXA 3BMBA 1GTPA 1WURA 2LO0A 4QPMA 1EFUB 4DU6A 1WPLA 4Q7JA 1IS8A 1FB1A 4R8QA 4NE3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E45 B;  4NE6 B;  3B0B C;  4E44 B;  4DRB J;  4DRA E;  4NE5 B;  4NE3 B; 
#chains in the Genus database with same CATH topology
 3VEJ A;  1EL6 A;  5DMZ A;  2LNZ A;  4DRB J;  1AIP C;  2WSF G;  2P11 A;  2O01 G;  2WSE G;  1N3R A;  1A9C A;  4JA3 A;  4E45 B;  4NE6 B;  3B0B C;  2KR1 A;  1WUQ A;  1IS7 A;  1N3S A;  2PN0 A;  1N3T A;  4DRA E;  4E44 B;  1WM9 A;  1A8R A;  3LW5 K;  4NE5 B;  1TFE A;  1FBX A;  2WSC K;  3BMB A;  1GTP A;  1WUR A;  3LW5 G;  2LO0 A;  4QPM A;  2WSC G;  1EFU B;  4DU6 A;  1WPL A;  4Q7J A;  1IS8 A;  2WSE K;  1FB1 A;  4R8Q A;  2WSF K;  4NE3 B; 
#chains in the Genus database with same CATH homology
 3VEJ A;  1EL6 A;  5DMZ A;  2LNZ A;  4DRB J;  1AIP C;  2P11 A;  1N3R A;  1A9C A;  4JA3 A;  4E45 B;  4NE6 B;  3B0B C;  2KR1 A;  1WUQ A;  1IS7 A;  1N3S A;  2PN0 A;  1N3T A;  4DRA E;  4E44 B;  1WM9 A;  1A8R A;  4NE5 B;  1TFE A;  1FBX A;  3BMB A;  1GTP A;  1WUR A;  2LO0 A;  4QPM A;  1EFU B;  4DU6 A;  1WPL A;  4Q7J A;  1IS8 A;  1FB1 A;  4R8Q A;  4NE3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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