4E44B

Crystal structure of the hmhf1/hmhf2 histone-fold tetramer
Total Genus 26
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
75
structure length
75
Chain Sequence
GSGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA
rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 26
structure length 75
sequence length 75
chains with identical sequence D
ec nomenclature
pdb deposition date 2012-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4e44B02
4E45B 4NE6B 4DRAE 4DRBJ 4E44B 4NE3B 3B0BC 4NE5B
chains in the Genus database with same CATH superfamily
2WSCG 4NE6B 4E45B 2WSFK 1N3RA 4JA3A 4E44B 4NE3B 2WSEK 1WURA 4Q7JA 3BMBA 2WSFG 1WPLA 1AIPC 1A8RA 2KR1A 2WSEG 2PN0A 4DU6A 1WUQA 3VEJA 1N3TA 4QPMA 1N3SA 1A9CA 2O01G 1FB1A 1FBXA 1EFUB 1WM9A 1TFEA 5DMZA 3LW5K 1GTPA 4NE5B 3LW5G 2P11A 4DRAE 4DRBJ 1IS8A 1IS7A 3B0BC 4R8QA 2WSCK 1EL6A 2LNZA 2LO0A
chains in the Genus database with same CATH topology
4E45B 4NE6B 1N3RA 4JA3A 4E44B 4NE3B 1WURA 4Q7JA 3BMBA 1WPLA 1AIPC 1A8RA 2KR1A 2PN0A 4DU6A 1WUQA 3VEJA 1N3TA 4QPMA 1N3SA 1A9CA 1FB1A 1FBXA 1EFUB 1WM9A 1TFEA 5DMZA 1GTPA 4NE5B 2P11A 4DRAE 4DRBJ 1IS8A 1IS7A 3B0BC 4R8QA 1EL6A 2LNZA 2LO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E45 B;  4NE6 B;  4DRA E;  4DRB J;  4E44 B;  4NE3 B;  3B0B C;  4NE5 B; 
#chains in the Genus database with same CATH topology
 2WSC G;  4NE6 B;  4E45 B;  2WSF K;  1N3R A;  4JA3 A;  4E44 B;  4NE3 B;  2WSE K;  1WUR A;  4Q7J A;  3BMB A;  2WSF G;  1WPL A;  1AIP C;  1A8R A;  2KR1 A;  2WSE G;  2PN0 A;  4DU6 A;  1WUQ A;  3VEJ A;  1N3T A;  4QPM A;  1N3S A;  1A9C A;  2O01 G;  1FB1 A;  1FBX A;  1EFU B;  1WM9 A;  1TFE A;  5DMZ A;  3LW5 K;  1GTP A;  4NE5 B;  3LW5 G;  2P11 A;  4DRA E;  4DRB J;  1IS8 A;  1IS7 A;  3B0B C;  4R8Q A;  2WSC K;  1EL6 A;  2LNZ A;  2LO0 A; 
#chains in the Genus database with same CATH homology
 4E45 B;  4NE6 B;  1N3R A;  4JA3 A;  4E44 B;  4NE3 B;  1WUR A;  4Q7J A;  3BMB A;  1WPL A;  1AIP C;  1A8R A;  2KR1 A;  2PN0 A;  4DU6 A;  1WUQ A;  3VEJ A;  1N3T A;  4QPM A;  1N3S A;  1A9C A;  1FB1 A;  1FBX A;  1EFU B;  1WM9 A;  1TFE A;  5DMZ A;  1GTP A;  4NE5 B;  2P11 A;  4DRA E;  4DRB J;  1IS8 A;  1IS7 A;  3B0B C;  4R8Q A;  1EL6 A;  2LNZ A;  2LO0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...