4E44 | Genus

Total Genus 26

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	26
sequence length	75
structure length	75
Chain Sequence	GSGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Dna binding protein
source organism	Homo sapiens
publication title	Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA rcsb
molecule keywords	Centromere protein S
total genus	26
structure length	75
sequence length	75
chains with identical sequence	D
ec nomenclature
pdb deposition date	2012-03-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF09415	CENP-X	CENP-S associating Centromere protein X

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.286.100	Mainly Alpha	Orthogonal Bundle	GTP Cyclohydrolase I; Chain A, domain 1	GTP Cyclohydrolase I; Chain A, domain 1	4e44B02

4NE5B 4NE6B 4E45B 4DRBJ 3B0BC 4E44B 4NE3B 4DRAE
chains in the Genus database with same CATH superfamily

4NE6B 1IS7A 2WSEK 2KR1A 2LO0A 2WSCG 1A8RA 1FB1A 1AIPC 2LNZA 4Q7JA 4DRAE 4NE5B 5DMZA 3LW5G 1N3SA 2WSCK 1TFEA 4DRBJ 1WUQA 4DU6A 4QPMA 4E44B 4R8QA 1A9CA 2PN0A 1WM9A 3LW5K 1IS8A 1N3TA 1GTPA 1WURA 1EL6A 1EFUB 2WSFG 1N3RA 4NE3B 2P11A 3BMBA 3VEJA 4E45B 4JA3A 2WSEG 3B0BC 1WPLA 2O01G 2WSFK 1FBXA
chains in the Genus database with same CATH topology

4NE6B 1IS7A 2KR1A 2LO0A 1A8RA 1FB1A 1AIPC 2LNZA 4Q7JA 4DRAE 4NE5B 5DMZA 4DRBJ 1N3SA 1TFEA 4DU6A 1WUQA 4QPMA 4E44B 4R8QA 1A9CA 2PN0A 1WM9A 1IS8A 1N3TA 1GTPA 1WURA 1EL6A 1EFUB 4NE3B 1N3RA 2P11A 3BMBA 3VEJA 4E45B 4JA3A 3B0BC 1WPLA 1FBXA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4NE5 B;  4NE6 B;  4E45 B;  4DRB J;  3B0B C;  4E44 B;  4NE3 B;  4DRA E; 
#chains in the Genus database with same CATH topology
 4NE6 B;  1IS7 A;  2WSE K;  2KR1 A;  2LO0 A;  2WSC G;  1A8R A;  1FB1 A;  1AIP C;  2LNZ A;  4Q7J A;  4DRA E;  4NE5 B;  5DMZ A;  3LW5 G;  1N3S A;  2WSC K;  1TFE A;  4DRB J;  1WUQ A;  4DU6 A;  4QPM A;  4E44 B;  4R8Q A;  1A9C A;  2PN0 A;  1WM9 A;  3LW5 K;  1IS8 A;  1N3T A;  1GTP A;  1WUR A;  1EL6 A;  1EFU B;  2WSF G;  1N3R A;  4NE3 B;  2P11 A;  3BMB A;  3VEJ A;  4E45 B;  4JA3 A;  2WSE G;  3B0B C;  1WPL A;  2O01 G;  2WSF K;  1FBX A; 
#chains in the Genus database with same CATH homology
 4NE6 B;  1IS7 A;  2KR1 A;  2LO0 A;  1A8R A;  1FB1 A;  1AIP C;  2LNZ A;  4Q7J A;  4DRA E;  4NE5 B;  5DMZ A;  4DRB J;  1N3S A;  1TFE A;  4DU6 A;  1WUQ A;  4QPM A;  4E44 B;  4R8Q A;  1A9C A;  2PN0 A;  1WM9 A;  1IS8 A;  1N3T A;  1GTP A;  1WUR A;  1EL6 A;  1EFU B;  4NE3 B;  1N3R A;  2P11 A;  3BMB A;  3VEJ A;  4E45 B;  4JA3 A;  3B0B C;  1WPL A;  1FBX A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4E44B

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations