4E44B

Crystal structure of the hmhf1/hmhf2 histone-fold tetramer
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
75
structure length
75
Chain Sequence
GSGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
source organism Homo sapiens
publication title Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA
rcsb
molecule keywords Centromere protein S
total genus 26
structure length 75
sequence length 75
chains with identical sequence D
ec nomenclature
pdb deposition date 2012-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4e44B02
4NE5B 4E45B 4DRAE 4E44B 4NE3B 4DRBJ 3B0BC 4NE6B
chains in the Genus database with same CATH superfamily
3VEJA 1WM9A 2WSCK 4DRAE 1N3RA 2KR1A 2P11A 2WSFG 1GTPA 1EL6A 2LO0A 2O01G 3LW5G 1AIPC 1N3SA 1A9CA 2WSEK 1TFEA 1WUQA 4QPMA 1EFUB 4E45B 1A8RA 1WPLA 2PN0A 4E44B 4DRBJ 3B0BC 5DMZA 1WURA 2WSFK 4NE5B 1N3TA 3LW5K 1IS8A 4DU6A 4NE6B 4JA3A 1FB1A 2WSCG 1IS7A 3BMBA 4R8QA 4NE3B 2LNZA 2WSEG 1FBXA 4Q7JA
chains in the Genus database with same CATH topology
3VEJA 1WM9A 4DRAE 1N3RA 2KR1A 2P11A 1GTPA 1EL6A 2LO0A 1AIPC 1N3SA 1A9CA 1TFEA 1WUQA 4QPMA 1EFUB 4E45B 1A8RA 1WPLA 2PN0A 4E44B 4DRBJ 3B0BC 5DMZA 1WURA 4NE5B 1N3TA 1IS8A 4DU6A 4NE6B 4JA3A 1FB1A 1IS7A 3BMBA 4R8QA 4NE3B 2LNZA 1FBXA 4Q7JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE5 B;  4E45 B;  4DRA E;  4E44 B;  4NE3 B;  4DRB J;  3B0B C;  4NE6 B; 
#chains in the Genus database with same CATH topology
 3VEJ A;  1WM9 A;  2WSC K;  4DRA E;  1N3R A;  2KR1 A;  2P11 A;  2WSF G;  1GTP A;  1EL6 A;  2LO0 A;  2O01 G;  3LW5 G;  1AIP C;  1N3S A;  1A9C A;  2WSE K;  1TFE A;  1WUQ A;  4QPM A;  1EFU B;  4E45 B;  1A8R A;  1WPL A;  2PN0 A;  4E44 B;  4DRB J;  3B0B C;  5DMZ A;  1WUR A;  2WSF K;  4NE5 B;  1N3T A;  3LW5 K;  1IS8 A;  4DU6 A;  4NE6 B;  4JA3 A;  1FB1 A;  2WSC G;  1IS7 A;  3BMB A;  4R8Q A;  4NE3 B;  2LNZ A;  2WSE G;  1FBX A;  4Q7J A; 
#chains in the Genus database with same CATH homology
 3VEJ A;  1WM9 A;  4DRA E;  1N3R A;  2KR1 A;  2P11 A;  1GTP A;  1EL6 A;  2LO0 A;  1AIP C;  1N3S A;  1A9C A;  1TFE A;  1WUQ A;  4QPM A;  1EFU B;  4E45 B;  1A8R A;  1WPL A;  2PN0 A;  4E44 B;  4DRB J;  3B0B C;  5DMZ A;  1WUR A;  4NE5 B;  1N3T A;  1IS8 A;  4DU6 A;  4NE6 B;  4JA3 A;  1FB1 A;  1IS7 A;  3BMB A;  4R8Q A;  4NE3 B;  2LNZ A;  1FBX A;  4Q7J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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