4JGHD

Structure of the socs2-elongin bc complex bound to an n-terminal fragment of cullin5
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
378
structure length
368
Chain Sequence
KGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Suppressor of cytokine signaling 2
total genus 135
structure length 368
sequence length 378
ec nomenclature
pdb deposition date 2013-03-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4jghD03
3DPLC 1LDKB 3RTRA 4N9F3 4HXIB 4AP2B 4APFB 1LDKA 1LDJA 4WQOD 3DQVC 4F52A 4JGHD 4P5OA 2WZKA 4EOZB 1U6GA 4A64A
chains in the Genus database with same CATH superfamily
3DPLC 2XU0A 3RRCA 3DQVC 4P5OA 1LDKB 4YFSA 4A64A 4N9F3 2PFVA 2B1EA 4APFB 5F3JA 4EOZB 3BQLA 2WAUA 4NUUA 3RTRA 3BQKA 3CPZA 2Y8DA 4WQOD 4JGHD 4AP2B 2WZKA 1LDKA 1U6GA 4NUVA 4HXIB 1LDJA 4F52A 3BQIA 3CMLA
chains in the Genus database with same CATH topology
3DPLC 1LDKB 3RTRA 4N9F3 4HXIB 4AP2B 4APFB 1LDKA 1LDJA 4WQOD 3DQVC 4F52A 4JGHD 4P5OA 2WZKA 4EOZB 1U6GA 4A64A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DPL C;  1LDK B;  3RTR A;  4N9F 3;  4HXI B;  4AP2 B;  4APF B;  1LDK A;  1LDJ A;  4WQO D;  3DQV C;  4F52 A;  4JGH D;  4P5O A;  2WZK A;  4EOZ B;  1U6G A;  4A64 A; 
#chains in the Genus database with same CATH topology
 3DPL C;  2XU0 A;  3RRC A;  3DQV C;  4P5O A;  1LDK B;  4YFS A;  4A64 A;  4N9F 3;  2PFV A;  2B1E A;  4APF B;  5F3J A;  4EOZ B;  3BQL A;  2WAU A;  4NUU A;  3RTR A;  3BQK A;  3CPZ A;  2Y8D A;  4WQO D;  4JGH D;  4AP2 B;  2WZK A;  1LDK A;  1U6G A;  4NUV A;  4HXI B;  1LDJ A;  4F52 A;  3BQI A;  3CML A; 
#chains in the Genus database with same CATH homology
 3DPL C;  1LDK B;  3RTR A;  4N9F 3;  4HXI B;  4AP2 B;  4APF B;  1LDK A;  1LDJ A;  4WQO D;  3DQV C;  4F52 A;  4JGH D;  4P5O A;  2WZK A;  4EOZ B;  1U6G A;  4A64 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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